2型糖尿病患者起始地特胰岛素治疗时的临床基线情况SOLVETM国际研究中国亚组结果
2형당뇨병환자기시지특이도소치료시적림상기선정황SOLVETM국제연구중국아조결과
The baseline characteristics of patients with type 2 diabetes initiating insulin detemir:the Chinese cohort from the SOLVETM study
  • 万方数据
    中华内科杂志 중화내과잡지
    CHINESE JOURNAL OF INTERNAL MEDICINE
    2012年 12期 957-961 ,共5页

    潘长玉%纪立农%陆菊明%杨文英%周智广%邹大进%姬秋和%韩萍%柳洁%李强%苏本利%李延兵%高政南%王鹏华%尹士男%董砚虎%杨涛%孙侃%李红%洪旭%林静%师静梅%杨小洁%房辉%颜晓东

    반장옥%기립농%륙국명%양문영%주지엄%추대진%희추화%한평%류길%리강%소본리%리연병%고정남%왕붕화%윤사남%동연호%양도%손간%리홍%홍욱%림정%사정매%양소길%방휘%안효동

    糖尿病,2型%胰岛素%治疗%数据收集 糖尿病,2型%胰島素%治療%數據收集
    당뇨병,2형%이도소%치료%수거수집
    Diabetes mellitus,type 2%Insulin%Therapy%Data collection
    目的 对诺和平1天1次注射研究(Study of Once-daily LeVEmir(R),SOLVETM)国际研究的中国亚组数据进行分析,了解中国2型糖尿病患者起始地特胰岛素时的基线特征.方法 由临床医生决定起始地特胰岛素治疗的2型糖尿病患者为人选对象.由医生记录基线时的人口统计学数据、病史、血糖控制情况和具体治疗方案.结果 共入选2型糖尿病患者3272例(女性占42％,男性占58％),年龄(56.2±10.8)岁,BMI (25.3±3.3) kg/m2,中位糖尿病病程4.0(0.1 ～27.0)年,中位口服降糖药物使用时间为3.0(0.0～20.2)年.515例(15.7％)受试者在基线时已经存在大血管并发症；886例(27.1％)存在微血管并发症.基线糖化血红蛋白(8.33±1.70)％,空腹血糖为(9.5±2.6)mmol/L.结论 中国2型糖尿病患者血糖控制差且并发症发生率高,血糖控制不佳的患者需要优化治疗方案.
    목적 대낙화평1천1차주사연구(Study of Once-daily LeVEmir(R),SOLVETM)국제연구적중국아조수거진행분석,료해중국2형당뇨병환자기시지특이도소시적기선특정.방법 유림상의생결정기시지특이도소치료적2형당뇨병환자위인선대상.유의생기록기선시적인구통계학수거、병사、혈당공제정황화구체치료방안.결과 공입선2형당뇨병환자3272례(녀성점42％,남성점58％),년령(56.2±10.8)세,BMI (25.3±3.3) kg/m2,중위당뇨병병정4.0(0.1 ～27.0)년,중위구복강당약물사용시간위3.0(0.0～20.2)년.515례(15.7％)수시자재기선시이경존재대혈관병발증；886례(27.1％)존재미혈관병발증.기선당화혈홍단백(8.33±1.70)％,공복혈당위(9.5±2.6)mmol/L.결론 중국2형당뇨병환자혈당공제차차병발증발생솔고,혈당공제불가적환자수요우화치료방안.
    Objective To characterize the baseline status of Chinese diabetic patients based on data derived from Chinese cohort from SOLVETM study.Methods Patients with type 2 diabetes initiating basal insulin detemir at the decision of the physician were eligible for the study.Data on demographics,medical history,glycemic profile and treatment regimen at baseline were collected by physicians.Results A total of 3272 patients [female 42％,male 58％,mean age (56.2 ± 10.8) years] were included in the study.Their BMI was (25.3 ± 3.3) kg/m2.The duration of diabetes was 4.0 (0.1-27.0) years,and the duration of treatment with oral antidiabetic drugs (OADs) was 3.0(0.0-20.2) years.The proportions of subjects with diabetic macro-and micro-vascular complications were 15.8％ (515 cases) and 27.1％ (866 cases),respectively.The hemoglobin Al c (HbAl c) at baseline was (8.33 ± 1.70) ％,and the fasting blood glucose (FPG) was (9.5 ± 2.6) mmol/L.Conclusions A large proportion of patients with type 2 diabetes remain in poor glycemic control,and the prevalence of diabetic complications is high,which requires optimal therapeutic strategy for the patients with suboptimal glycemic control.
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