CAJ | 학술논문

目的探讨帕金森病患者疲劳和抑郁的相关性.方法选取帕金森病患者56例,疲劳严重度量表(FSS)评价患者的疲劳程度,Hamilton抑郁量表(HAMD)评价患者的抑郁程度,帕金森病生活质量问卷(PDQL)评价患者的生活质量,并进行UPDRSⅢ、Hoehn-Yahr分期评定、改良Webster评分.结果患者疲劳的发生率为71.4％(40/56).HAMD评分、PDQL总分与患者疲劳相关,偏相关系数分别为0.451 (P＜0.01)、-0.346(P ＜0.05).无抑郁患者疲劳发生率较低,为27.3％,抑郁组疲劳发生率较高,其中轻度、中度和重度抑郁疲劳发生率分别为75％,100％,100％.结论疲劳感是帕金森病患者抑郁的重要表现,也可以是独立于抑郁之外的非运动症状,同样影响着帕金森病患者的生活质量.
목적 탐토파금삼병환자피로화억욱적상관성.방법 선취파금삼병환자56례,피로엄중도량표(FSS)평개환자적피로정도,Hamilton억욱량표(HAMD)평개환자적억욱정도,파금삼병생활질량문권(PDQL)평개환자적생활질량,병진행UPDRSⅢ、Hoehn-Yahr분기평정、개량Webster평분.결과 환자피로적발생솔위71.4％(40/56).HAMD평분、PDQL총분여환자피로상관,편상관계수분별위0.451 (P＜0.01)、-0.346(P ＜0.05).무억욱환자피로발생솔교저,위27.3％,억욱조피로발생솔교고,기중경도、중도화중도억욱피로발생솔분별위75％,100％,100％.결론 피로감시파금삼병환자억욱적중요표현,야가이시독립우억욱지외적비운동증상,동양영향착파금삼병환자적생활질량.
Objective To identify the association between fatigue and depression in Parkinson's disease(PD).Methods 56 PD patients were enrolled in this study.The degree of fatigue was measured by Fatigue Severity Scale (FSS).Hamilton Depression Scale (24 items) was used to evaluate the degree of depression.PD Quality of Life Questionnaire (PDQL) were tested to evaluate the quality of life in PD patients.While other clinical information such as Unified Parkinson's Disease Rating Scale (UPDRS) Ⅲ,Hoehn-Yahr Scale and modified Webster Scale were investigated.Results The incidence of fatigue in this group is 71.4％ (40/56).Score of HAMD and PDQL exhibited a significant correlation to patients' fatigue,coefficient of partial correlation was 0.451 (P ＜ 0.01),-0.346 (P ＜ 0.05).The incidence of fatigue in non-depressive patients was low,27.3 ％.While in depressive patients,the incidence of fatigue is relatively high,for mild depression 75％,moderate depression 100％,severe depression 100％ respectively.Conclusions Fatigue is a prominent symptom of depression in PD patients,sometimes independent of depression also influencing the patients' quality of life.