中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2014年
4期
269-272
,共4页
王娟%杨艳敏%朱俊%邵兴慧%张晗%李建冬%刘力生
王娟%楊豔敏%硃俊%邵興慧%張晗%李建鼕%劉力生
왕연%양염민%주준%소흥혜%장함%리건동%류력생
心房颤动%高血压%脑血管意外%危险因素
心房顫動%高血壓%腦血管意外%危險因素
심방전동%고혈압%뇌혈관의외%위험인소
Atrial fibrillation%Hypertension%Cerebrovascular accident%Risk factors
目的 探讨心房颤动(房颤)合并高血压患者1年随访的卒中发生率及其危险因素.方法 分析中国急诊房颤注册研究(20家医院)的房颤合并高血压患者资料,根据1年随访事件中是否发生卒中将患者分为卒中组和非卒中组.用单因素和多因素Cox回归模型分析影响房颤合并高血压患者1年卒中发生的独立危险因素.结果 共入选1 118例房颤合并高血压患者,其中卒中组97例,非卒中组1 021例,1年卒中发生率为8.7％.卒中组年龄显著高于非卒中组[(76.0±9.4)岁比(71.9±10.6)岁,P＜0.01],卒中组女性、既往卒中史所占比例高于非卒中组(68.0％比54.5％,38.1％比23.8％,P值均＜0.05).非卒中组接受抗高血压治疗比例高于卒中组(91.6％比85.6％,P＜0.05).卒中组患者他汀类药物的应用比例高于非卒中组(45.4％比34.5％,P＜0.05).多因素Cox回归模型分析显示,年龄(HR=1.036,95％CI1.010 ～1.062)、女性(HR=1.908,95％CI1.170～3.110)、未接受抗高血压治疗(HR=1.955,95％ CI1.008 ～ 3.791)、既往卒中史(HR=1.680,95％CI1.084 ～2.603)是房颤合并高血压患者1年卒中发生的独立危险因素.结论 年龄、女性、未接受抗高血压治疗和既往卒中史是房颤合并高血压患者1年卒中发生的独立危险因素.
目的 探討心房顫動(房顫)閤併高血壓患者1年隨訪的卒中髮生率及其危險因素.方法 分析中國急診房顫註冊研究(20傢醫院)的房顫閤併高血壓患者資料,根據1年隨訪事件中是否髮生卒中將患者分為卒中組和非卒中組.用單因素和多因素Cox迴歸模型分析影響房顫閤併高血壓患者1年卒中髮生的獨立危險因素.結果 共入選1 118例房顫閤併高血壓患者,其中卒中組97例,非卒中組1 021例,1年卒中髮生率為8.7％.卒中組年齡顯著高于非卒中組[(76.0±9.4)歲比(71.9±10.6)歲,P＜0.01],卒中組女性、既往卒中史所佔比例高于非卒中組(68.0％比54.5％,38.1％比23.8％,P值均＜0.05).非卒中組接受抗高血壓治療比例高于卒中組(91.6％比85.6％,P＜0.05).卒中組患者他汀類藥物的應用比例高于非卒中組(45.4％比34.5％,P＜0.05).多因素Cox迴歸模型分析顯示,年齡(HR=1.036,95％CI1.010 ～1.062)、女性(HR=1.908,95％CI1.170～3.110)、未接受抗高血壓治療(HR=1.955,95％ CI1.008 ～ 3.791)、既往卒中史(HR=1.680,95％CI1.084 ～2.603)是房顫閤併高血壓患者1年卒中髮生的獨立危險因素.結論 年齡、女性、未接受抗高血壓治療和既往卒中史是房顫閤併高血壓患者1年卒中髮生的獨立危險因素.
목적 탐토심방전동(방전)합병고혈압환자1년수방적졸중발생솔급기위험인소.방법 분석중국급진방전주책연구(20가의원)적방전합병고혈압환자자료,근거1년수방사건중시부발생졸중장환자분위졸중조화비졸중조.용단인소화다인소Cox회귀모형분석영향방전합병고혈압환자1년졸중발생적독립위험인소.결과 공입선1 118례방전합병고혈압환자,기중졸중조97례,비졸중조1 021례,1년졸중발생솔위8.7％.졸중조년령현저고우비졸중조[(76.0±9.4)세비(71.9±10.6)세,P＜0.01],졸중조녀성、기왕졸중사소점비례고우비졸중조(68.0％비54.5％,38.1％비23.8％,P치균＜0.05).비졸중조접수항고혈압치료비례고우졸중조(91.6％비85.6％,P＜0.05).졸중조환자타정류약물적응용비례고우비졸중조(45.4％비34.5％,P＜0.05).다인소Cox회귀모형분석현시,년령(HR=1.036,95％CI1.010 ～1.062)、녀성(HR=1.908,95％CI1.170～3.110)、미접수항고혈압치료(HR=1.955,95％ CI1.008 ～ 3.791)、기왕졸중사(HR=1.680,95％CI1.084 ～2.603)시방전합병고혈압환자1년졸중발생적독립위험인소.결론 년령、녀성、미접수항고혈압치료화기왕졸중사시방전합병고혈압환자1년졸중발생적독립위험인소.
Objective To explore the independent risk factors for the 1 year stroke event in Chinese patients with atrial fibrillation (AF) and hypertension (HT).Methods Data of AF and HT patients in the Chinese Emergency Atrial Fibrillation Registry Study were retrospectively analyzed.The eligible patients were divided into the stroke group and the non-stroke group according to the result of 1 year follow-up.The predictors for the 1 year stroke event were identified by uni-and multi-variate Cox regression analysis with the baseline and therapeutic variables.Results A total of 1 118 AF and HT patients were enrolled in the study with the incidence of 1 year stroke event of 8.7％.All patients were divided into the stroke group (n =97) and the non-stroke group (n =1 021).Compared with the non-stroke group,more female patients were in the stroke group (68.0％ vs 54.5％,P ＜ 0.05) and the patients in the stroke group were older [(76.0 ± 9.4) years vs (71.9 ± 10.6) years,P ＜ 0.01] with higher proportion of previous history of stroke (38.1％ vs 23.8％,P ＜0.01).More patients were observed on the antihypertensive treatment in the non-stroke group (91.6％ vs 85.6％,P ＜ 0.05),while more patients on statins in the stroke group(45.4％vs 34.5％,P ＜ 0.05).Multi-variate Cox regression analysis showed that age (HR =1.036,95％ CI 1.010-1.062),female (HR =1.908,95％ CI 1.170-3.110),previous stroke history (HR =1.680,95％ CI 1.084-2.603),and no antihypertensive treatment (HR =1.955,95％ CI 1.008-3.791) were independent risk factors for the 1 year stroke event in patients with AF and HT.Conclusion Age,female,previous stroke history and no antihypertensive treatment are the independent risk factors for the 1 year stroke event in patients with AF and HT.
