中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2014年
7期
542-545
,共4页
孙启虹%巴建明%陈康%闫文华%王先令%谷伟军%汪保安%王健松%王淑梅
孫啟虹%巴建明%陳康%閆文華%王先令%穀偉軍%汪保安%王健鬆%王淑梅
손계홍%파건명%진강%염문화%왕선령%곡위군%왕보안%왕건송%왕숙매
代谢综合征X%骨密度%定量超声
代謝綜閤徵X%骨密度%定量超聲
대사종합정X%골밀도%정량초성
Metabolic syndrome X%Bone density%Quantitative ultrasound
目的 探索定量超声检测跟骨骨密度(BMD)与代谢综合征(MS)及其各组分之间的关系.方法 横断面研究,对象为北京某社区常住居民.按性别、绝经与否分组,每组再分为MS和非MS组,分析MS对BMD的影响.MS采用中华医学会糖尿病学分会制定的诊断标准.结果 5 552例受试者纳入分析.男女比例1:1.8,年龄40～87岁,其中,男1 987例,年龄(59.4±7.3)岁;女3 565例,年龄(56.9±7.2)岁,绝经前后女性比例1:3.7.MS患病率:男29.0％,女24.4％.协方差分析显示,MS组与非MS组BMD差异无统计学意义.但是随着MS组分数目由0个增加至4个,绝经后女性BMD有增加的趋势,协方差分析显示,BMD的增加有统计学意义(P＜0.05).多元线性回归分析提示绝经后女性MS组的BMD与年龄呈负相关(β=-0.034,P＜0.001)、与BMI(β=0.046,P=0.001)、收缩压(β =0.007,P=0.039)、TG(β=0.066,P=0.034)呈正相关.结论 随着MS组分数目的增加,绝经后女性BMD有增加的趋势,BMD与BMI、收缩压、TG呈正相关.
目的 探索定量超聲檢測跟骨骨密度(BMD)與代謝綜閤徵(MS)及其各組分之間的關繫.方法 橫斷麵研究,對象為北京某社區常住居民.按性彆、絕經與否分組,每組再分為MS和非MS組,分析MS對BMD的影響.MS採用中華醫學會糖尿病學分會製定的診斷標準.結果 5 552例受試者納入分析.男女比例1:1.8,年齡40～87歲,其中,男1 987例,年齡(59.4±7.3)歲;女3 565例,年齡(56.9±7.2)歲,絕經前後女性比例1:3.7.MS患病率:男29.0％,女24.4％.協方差分析顯示,MS組與非MS組BMD差異無統計學意義.但是隨著MS組分數目由0箇增加至4箇,絕經後女性BMD有增加的趨勢,協方差分析顯示,BMD的增加有統計學意義(P＜0.05).多元線性迴歸分析提示絕經後女性MS組的BMD與年齡呈負相關(β=-0.034,P＜0.001)、與BMI(β=0.046,P=0.001)、收縮壓(β =0.007,P=0.039)、TG(β=0.066,P=0.034)呈正相關.結論 隨著MS組分數目的增加,絕經後女性BMD有增加的趨勢,BMD與BMI、收縮壓、TG呈正相關.
목적 탐색정량초성검측근골골밀도(BMD)여대사종합정(MS)급기각조분지간적관계.방법 횡단면연구,대상위북경모사구상주거민.안성별、절경여부분조,매조재분위MS화비MS조,분석MS대BMD적영향.MS채용중화의학회당뇨병학분회제정적진단표준.결과 5 552례수시자납입분석.남녀비례1:1.8,년령40～87세,기중,남1 987례,년령(59.4±7.3)세;녀3 565례,년령(56.9±7.2)세,절경전후녀성비례1:3.7.MS환병솔:남29.0％,녀24.4％.협방차분석현시,MS조여비MS조BMD차이무통계학의의.단시수착MS조분수목유0개증가지4개,절경후녀성BMD유증가적추세,협방차분석현시,BMD적증가유통계학의의(P＜0.05).다원선성회귀분석제시절경후녀성MS조적BMD여년령정부상관(β=-0.034,P＜0.001)、여BMI(β=0.046,P=0.001)、수축압(β =0.007,P=0.039)、TG(β=0.066,P=0.034)정정상관.결론 수착MS조분수목적증가,절경후녀성BMD유증가적추세,BMD여BMI、수축압、TG정정상관.
Objective To evaluate the association between calcaneus bone mineral density (BMD) and metabolic syndrome (MS).Methods A cross-sectional study was carried out in 5 552 subjects with 1 987 men and 3 565 women (age:40-87 years old).MS was defined according to Chinese Diabetes Society criteria.BMD was assessed by quantitative ultrasound.Results The proportion of MS was 29.0％ in male and 24.4％ in female.There were no differences in BMD between MS and non-MS subjects in both genders.Linear trend analysis displayed that BMD was positively associated with the increase of MS components in post-menopausal women after adjustment of age,ALT,creatinine and exercises (P ＜ 0.05).Moreover,multiple regression analysis showed that BMD was inversely correlated with age (β =-0.034,P ＜ 0.001) and positively correlated with BMI(β =0.046,P =0.001),TG (β =0.066,P =0.034) and systolic blood pressure(SBP) (β =0.007,P =0.039) in post-menopausal women with MS.Conclusions BMD tended to increase with the numbers of MS components in post-menopausal women.It was positively correlated with BMI,TG and SBP in postmenopausal women with MS.
