中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
8期
1048-1050
,共3页
高尿酸血症%冠心病%性别%危险因素
高尿痠血癥%冠心病%性彆%危險因素
고뇨산혈증%관심병%성별%위험인소
Hyperuricemia%Coronary heart disease%Gender%Risk factor
目的 探讨高尿酸血症与冠心病患者性别的关系.方法 选取2012年3-9月于安贞医院急诊综合病房住院患者75例.将40例冠心病患者按性别分为男性冠心病组和女性冠心病组,各20例；同期入组的对照组为经冠状动脉造影证实冠状动脉正常的疑似冠心病患者,男20例,女15例,回顾性收集入选受试者的资料,比较2组患者的年龄、血尿酸、空腹血糖、血肌酐、血脂的情况.结果 男、女冠心病组的平均血尿酸水平未达到高尿酸血症的标准[(351±67)μmol/L、(310 ±74) μmol/L],男性冠心病组尿酸水平高于女性冠心病组(P＜0.05).男性冠心病组尿酸水平与男性对照组[(327±82)μmol/L]比较差异无统计学意义(P＞0.05).女性冠心病组尿酸水平显著高于女性对照组[(216 ±52) μmol/L],差异有统计学意义(P＜0.01).女性冠心病组的HDL-C[(1.09±0.19) mmol/L]低于女性对照组[(1.27±0.23) mmol/L](P＜0.05),而TG[(1.6±0.6)mmol/L]高于女性对照组[(1.1 ±0.4)mmol/L](P＜0.05).结论 高尿酸血症可能是女性冠心病患者的一个危险因素.
目的 探討高尿痠血癥與冠心病患者性彆的關繫.方法 選取2012年3-9月于安貞醫院急診綜閤病房住院患者75例.將40例冠心病患者按性彆分為男性冠心病組和女性冠心病組,各20例；同期入組的對照組為經冠狀動脈造影證實冠狀動脈正常的疑似冠心病患者,男20例,女15例,迴顧性收集入選受試者的資料,比較2組患者的年齡、血尿痠、空腹血糖、血肌酐、血脂的情況.結果 男、女冠心病組的平均血尿痠水平未達到高尿痠血癥的標準[(351±67)μmol/L、(310 ±74) μmol/L],男性冠心病組尿痠水平高于女性冠心病組(P＜0.05).男性冠心病組尿痠水平與男性對照組[(327±82)μmol/L]比較差異無統計學意義(P＞0.05).女性冠心病組尿痠水平顯著高于女性對照組[(216 ±52) μmol/L],差異有統計學意義(P＜0.01).女性冠心病組的HDL-C[(1.09±0.19) mmol/L]低于女性對照組[(1.27±0.23) mmol/L](P＜0.05),而TG[(1.6±0.6)mmol/L]高于女性對照組[(1.1 ±0.4)mmol/L](P＜0.05).結論 高尿痠血癥可能是女性冠心病患者的一箇危險因素.
목적 탐토고뇨산혈증여관심병환자성별적관계.방법 선취2012년3-9월우안정의원급진종합병방주원환자75례.장40례관심병환자안성별분위남성관심병조화녀성관심병조,각20례；동기입조적대조조위경관상동맥조영증실관상동맥정상적의사관심병환자,남20례,녀15례,회고성수집입선수시자적자료,비교2조환자적년령、혈뇨산、공복혈당、혈기항、혈지적정황.결과 남、녀관심병조적평균혈뇨산수평미체도고뇨산혈증적표준[(351±67)μmol/L、(310 ±74) μmol/L],남성관심병조뇨산수평고우녀성관심병조(P＜0.05).남성관심병조뇨산수평여남성대조조[(327±82)μmol/L]비교차이무통계학의의(P＞0.05).녀성관심병조뇨산수평현저고우녀성대조조[(216 ±52) μmol/L],차이유통계학의의(P＜0.01).녀성관심병조적HDL-C[(1.09±0.19) mmol/L]저우녀성대조조[(1.27±0.23) mmol/L](P＜0.05),이TG[(1.6±0.6)mmol/L]고우녀성대조조[(1.1 ±0.4)mmol/L](P＜0.05).결론 고뇨산혈증가능시녀성관심병환자적일개위험인소.
Objective To discuss the relations between hyperuricemia (HUA) and gender of patients with coronary heart disease (CHD).Methods Seventy-five patients hospitalized in department of emergency during of Anzhen Hospital from March 2012 to September 2012 were selected.Forty patients were divided into male CHD group and female CHD group by gender,each group had 20 cases; there were twenty male controls and fifteen female controls were selected at the same time.The subjects' data were retrospectively collected,age,serum uric acid,fasting blood-glucose,serum creatinine,blood lipid of two groups were compared respectively.Results The average blood uric acid level of female-CHD,male-CHD groups has not reached the standard of HUA [(351 ± 67) μmol/L,(310 ±75)μmol/L],the serum uric acid levels of male-CHD group was higher than that of female-CHD group(P ＜ 0.05).There was significant difference on serum uric acid level of male-CHD group [(351 ±67)μmol/L] compared with that of male control group [(327 ± 82) μmol/L] (P ＞ 0.05).The serum uric acid level female-CHD group [(310 ±757)μmol/L] was significantly higher than that of female control group [(216 ±52)μmol/L] (P ＜ 0.01).The high-density cholesterol of female-CHD group [(1.09 ± 0.19) mmol/L] was lower than that of female control group [(1.27 ± 0.23) mmol/L] (P ＜ 0.05),but triglycerides of female-CHD group [(1.6 ± 0.6) mmol/L] was higher than that of female control group [(1.1 ± 0.4) mmol/L] (P ＜ 0.05).Conclusion HUA may be a risk factor for female patients with CHD.
