中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
8期
1053-1054
,共2页
卢新%于大勇%任平香%李丽%郭菊秋%王冬梅
盧新%于大勇%任平香%李麗%郭菊鞦%王鼕梅
로신%우대용%임평향%리려%곽국추%왕동매
重症%冠心病%N末端-前B型钠尿肽%心肌肌钙蛋白%相关
重癥%冠心病%N末耑-前B型鈉尿肽%心肌肌鈣蛋白%相關
중증%관심병%N말단-전B형납뇨태%심기기개단백%상관
Severe%Coronary heart disease%N terminal pro-B-type natriuretic peptide%Cardiac troponin%Correlation
目的 研究重症冠心病患者N末端-前B型钠尿肽与心肌肌钙蛋白的相关性.方法 收集2012年1-12月在唐山市丰润区人民医院ICU及CCU住院的282例重症冠心病患者临床数据,根据诊断分为急性心肌梗死组(104例)、急性心力衰竭组(60例)和不稳定型心绞痛组(118例).采用非参数Spearman检验进行数值相关性分析.结果 N末端-前B型钠尿肽与心肌肌钙蛋白呈中度正相关(P＜0.01),其中心肌梗死组的N末端-前B型钠尿肽与心肌肌钙蛋白T的相关系数r=0.569(P＜0.01),与心肌肌钙蛋白I的相关系数r =0.568(P ＜0.01).心肌肌钙蛋白T与心肌肌钙蛋白I的相关系数r=0.999(P ＜0.01),它们之间具有良好的线性关系.结论 N末端-前B型钠尿肽与心肌肌钙蛋白呈中度正相关.心肌肌钙蛋白T与心肌肌钙蛋白I呈高度正相关.
目的 研究重癥冠心病患者N末耑-前B型鈉尿肽與心肌肌鈣蛋白的相關性.方法 收集2012年1-12月在唐山市豐潤區人民醫院ICU及CCU住院的282例重癥冠心病患者臨床數據,根據診斷分為急性心肌梗死組(104例)、急性心力衰竭組(60例)和不穩定型心絞痛組(118例).採用非參數Spearman檢驗進行數值相關性分析.結果 N末耑-前B型鈉尿肽與心肌肌鈣蛋白呈中度正相關(P＜0.01),其中心肌梗死組的N末耑-前B型鈉尿肽與心肌肌鈣蛋白T的相關繫數r=0.569(P＜0.01),與心肌肌鈣蛋白I的相關繫數r =0.568(P ＜0.01).心肌肌鈣蛋白T與心肌肌鈣蛋白I的相關繫數r=0.999(P ＜0.01),它們之間具有良好的線性關繫.結論 N末耑-前B型鈉尿肽與心肌肌鈣蛋白呈中度正相關.心肌肌鈣蛋白T與心肌肌鈣蛋白I呈高度正相關.
목적 연구중증관심병환자N말단-전B형납뇨태여심기기개단백적상관성.방법 수집2012년1-12월재당산시봉윤구인민의원ICU급CCU주원적282례중증관심병환자림상수거,근거진단분위급성심기경사조(104례)、급성심력쇠갈조(60례)화불은정형심교통조(118례).채용비삼수Spearman검험진행수치상관성분석.결과 N말단-전B형납뇨태여심기기개단백정중도정상관(P＜0.01),기중심기경사조적N말단-전B형납뇨태여심기기개단백T적상관계수r=0.569(P＜0.01),여심기기개단백I적상관계수r =0.568(P ＜0.01).심기기개단백T여심기기개단백I적상관계수r=0.999(P ＜0.01),타문지간구유량호적선성관계.결론 N말단-전B형납뇨태여심기기개단백정중도정상관.심기기개단백T여심기기개단백I정고도정상관.
Objective To study the correlation between N terminal pro-B-type natriuretic peptide and cardiac troponin in patients with severe coronary artery disease.Methods The clinical data of 282 hospitalized patients in ICU and CCU with severe coronary artery disease were retrospectively observed from January to December 2012.The patients were divided into acute myocardial infarction group (AMI,104),acute heart failure group (AHF,60) and acute coronary syndrome group (ACS,118).The correlations were analyzed through the nonparametric Spearman test.Results The correlations between N terminal pro-B-type natriuretic peptide and cardiac troponin was positively moderate(P ＜0.01),while correlation coefficient of N terminal pro-B-type natriuretic peptide and cardiac troponin T was 0.569 (P ＜ 0.01),correlation coefficients of N terminal pro-B-type natriuretic peptide and cardiac troponin I was 0.568 (P ＜ 0.01) in acute myocardial infarction group.Correlation coefficient of cardiac troponin T and cardiac troponin I was 0.999 (P ＜ 0.01).There was a good linear relation between them.Conclusions There is a moderately positive correlation between N terminal pro-B-type natriuretic peptide and cardiac troponin.There is a highly positive correlation between cardiac troponin T and cardiac troponin I.
