CAJ | 학술논문

目的探讨灵活设置胰岛素泵基础率控制围手术期糖尿病患者血糖的临床效果.方法将重庆三峡中心医院40例择期手术的2型糖尿病患者按随机数字表法分为试验组(20例)和对照组(20例).2组患者均使用胰岛素泵,试验组采用固定短时间高剂量基础率代替餐前大剂量输注,对照组采用常规大剂量注射方式.观察2组患者的血糖达标时间、空腹血糖、非空腹血糖、血糖监测次数、低血糖发生率.结果试验组患者血糖达标时间[(3.5±2.2)d]短于对照组[(6.1±2.5)d],差异有统计学意义(P＜0.05)；空腹血糖[(5.3±1.5)mmol/L]、非空腹血糖[(7.5±2.2) mmol/L]、血糖监测次数[(31±4)次]、低血糖发生率[(5.1±2.4)％]与对照组[(5.6±1.2) mmol/L、(8.1±1.5) mmol/L、(29±6)次、(5.1±2.1)％]比较,差异均无统计学意义(均P ＞0.05).结论灵活设置胰岛素泵,采用固定短时间高剂量基础率代替餐前大剂量输注控制围手术期糖尿病患者血糖是一种安全有效的方法.
목적 탐토령활설치이도소빙기출솔공제위수술기당뇨병환자혈당적림상효과.방법 장중경삼협중심의원40례택기수술적2형당뇨병환자안수궤수자표법분위시험조(20례)화대조조(20례).2조환자균사용이도소빙,시험조채용고정단시간고제량기출솔대체찬전대제량수주,대조조채용상규대제량주사방식.관찰2조환자적혈당체표시간、공복혈당、비공복혈당、혈당감측차수、저혈당발생솔.결과 시험조환자혈당체표시간[(3.5±2.2)d]단우대조조[(6.1±2.5)d],차이유통계학의의(P＜0.05)；공복혈당[(5.3±1.5)mmol/L]、비공복혈당[(7.5±2.2) mmol/L]、혈당감측차수[(31±4)차]、저혈당발생솔[(5.1±2.4)％]여대조조[(5.6±1.2) mmol/L、(8.1±1.5) mmol/L、(29±6)차、(5.1±2.1)％]비교,차이균무통계학의의(균P ＞0.05).결론 령활설치이도소빙,채용고정단시간고제량기출솔대체찬전대제량수주공제위수술기당뇨병환자혈당시일충안전유효적방법.
Objective To explore the clinical effect on the basic rate of insulin pump through flexible setting in the controlling of blood glucose of patients with diabetics during perioperative period.Methods Forty type 2 diabetics patients undergoing selective operation in Chongqing Three Gorges Central Hospital were divided into experimental group (20 cases) and control group (20 cease) according to the random number table.Patients of two groups were given insulin pump,experimental group adopted the fixed short time high dose rate instead of the supplemental dose infusion,and the control group used conventional high-dose injection.The time of blood glucose controlled-compliance,fasting blood-glucose,non-fasting blood glucose,number of blood glucose monitoring and incidence of hypoglycemia of two groups were observed.Results There were significant differences on the time of blood glucose controlled-compliance of experimental group [(3.5 ± 2.2) d] when compared with control group (P ＜0.05).There were significant differences on fasting blood-glucose,non-fasting blood glucose,number of blood glucose monitoring and incidence of hypoglycemia of observation group [(5.3 ± 1.5) mmol/L,(7.5 ± 2.2) mmol/L,(31 ± 4) times,(5.1 ± 2.4) ％] when compared with control group [(5.6 ± 1.2) mmol/L,(8.1 ± 1.5) mmol/L,(29 ± 6) times,(5.1 ± 2.1) ％] (P ＞ 0.05).Conclusion Adopting the fixed short time high dose rate instead of the supplemental dose infusion can be a safe and effective method to control the blood glucose of diabetics in perioperative period.