CAJ | 학술논문

目的观察注射用益气复脉治疗急性分水岭脑梗死的临床效果.方法 80例急性分水岭脑梗死患者完全随机分为观察组(40例),对照组(40例).2组均给予抗血小板聚集、调脂、调控血压、改善微循环及保护脑细胞等治疗,观察组在此基础上加用注射用益气复脉,5.2 g/d静脉滴注,共10 d.治疗前后应用美国国立卫生研究院卒中量表(NIHSS)进行神经功能缺损评分.结果 2组患者治疗后NIHSS评分均低于本组治疗前[观察组(8.4±2.5)分比(13.2±2.3)分,对照组(9.6±3.2)分比(13.4±2.7)分],观察组治疗后NIHSS评分明显低于对照组(P＜0.05).观察组治疗有效率为85.0％(34/40),明显高于对照组的65.0％ (26/40)(P＜0.05).2组均无明显不良反应.结论注射用益气复脉治疗分水岭脑梗死安全、有效.
목적 관찰주사용익기복맥치료급성분수령뇌경사적림상효과.방법 80례급성분수령뇌경사환자완전수궤분위관찰조(40례),대조조(40례).2조균급여항혈소판취집、조지、조공혈압、개선미순배급보호뇌세포등치료,관찰조재차기출상가용주사용익기복맥,5.2 g/d정맥적주,공10 d.치료전후응용미국국립위생연구원졸중량표(NIHSS)진행신경공능결손평분.결과 2조환자치료후NIHSS평분균저우본조치료전[관찰조(8.4±2.5)분비(13.2±2.3)분,대조조(9.6±3.2)분비(13.4±2.7)분],관찰조치료후NIHSS평분명현저우대조조(P＜0.05).관찰조치료유효솔위85.0％(34/40),명현고우대조조적65.0％ (26/40)(P＜0.05).2조균무명현불량반응.결론 주사용익기복맥치료분수령뇌경사안전、유효.
Objective To evaluate the efficacy of Yiqifumai injection on cerebral watershed infarction.Methods Eighty patients with cerebral infarction were randomly divided into observation group (n =40) and control group (n =40).Two groups received anti-platelet aggregation,lipid and blood pressure regulation to improve microcirculation.Neurological deficit was assessed by the national institute of health stroke scale (NIHSS) before and after treatment.Results After treatment,NIHSS sores were lower than those before treatment in both groups [observation group (8.4 ± 2.5) scores vs (13.2 ± 2.3) scores,control group (9.6 ± 3.2) scores vs (13.4 ± 2.7) scores] ; NIHSS score in the observation group was significantly lower than that in the control group(P ＜ 0.05).The efficacy in the observation group was superior to that in the control group [85.0％ (34/40) vs 65.0％ (26/ 40)] (P ＜ 0.05).There were no obvious adverse reactions in two groups.There were no obvious adverse effects in two groups.Conclusion Yiqifumai injection is safe and effective for treating cerebral watershed infarction.