CAJ | 학술논문

目的探讨病毒性脑炎患儿的脑电图及影像学特点.方法对2011年6月至2013年6月在湖南省儿童医院治疗的20例重症病毒性脑炎的脑电图、影像学及脑脊液检查结果进行回顾性分析.结果 20例患儿脑电图检查均有不同程度异常,且脑电图异常随病情的进展而变化,早期表现为背景节律慢化,波幅降低.脑脊液异常表现为压力增高10例,白细胞轻度增高6例,以淋巴细胞增高为主,蛋白轻度增高5例.脑脊液细菌培养均阴性,特异性病毒抗体检测仅2例阳性,均为单疱病毒.11例MRI异常.病变大多呈双侧对称性,少数病灶不对称.其中病变累及1个部位者4例(41.6％).基底节异常信号6例,额叶3例,脑干5例,大脑脚2例,中脑2例,枕区异常信号3例,视神经受损2例.5例CT正常而MRI表现为小脑、脑干异常信号,增强扫描均无明显强化,3例MRI脑、脊髓均有异常信号,且临床亦同时有脊髓炎的表现.结论病毒性脑炎患儿脑电图均有异常,脑电图改变的程度与患儿病情严重程度相关,随病情的好转而好转.脑电图对病毒性脑炎早期诊断及判断预后有重要意义.
목적 탐토병독성뇌염환인적뇌전도급영상학특점.방법 대2011년6월지2013년6월재호남성인동의원치료적20례중증병독성뇌염적뇌전도、영상학급뇌척액검사결과진행회고성분석.결과 20례환인뇌전도검사균유불동정도이상,차뇌전도이상수병정적진전이변화,조기표현위배경절률만화,파폭강저.뇌척액이상표현위압력증고10례,백세포경도증고6례,이림파세포증고위주,단백경도증고5례.뇌척액세균배양균음성,특이성병독항체검측부2례양성,균위단포병독.11례MRI이상.병변대다정쌍측대칭성,소수병조불대칭.기중병변루급1개부위자4례(41.6％).기저절이상신호6례,액협3례,뇌간5례,대뇌각2례,중뇌2례,침구이상신호3례,시신경수손2례.5례CT정상이MRI표현위소뇌、뇌간이상신호,증강소묘균무명현강화,3례MRI뇌、척수균유이상신호,차림상역동시유척수염적표현.결론 병독성뇌염환인뇌전도균유이상,뇌전도개변적정도여환인병정엄중정도상관,수병정적호전이호전.뇌전도대병독성뇌염조기진단급판단예후유중요의의.
Objective To analyze characteristics of electroencephalogram (EEG) in children with viral encephalitis.Methods The EEG,image and cerebrospinal fluid of 20 children with severe viral encephalitis were retrospectively analyzed at Hunan Children's hospital from June 2011 to June 2013.Results Totally 20 cases of children had EEG examination.Abnormal EEG was associated with the progress of the disease.Early EEG showed slower rhythm and lower volatility.10 cases had increasing cerebrospinal fluid pressure.Cerebrospinal fluid bacterial cultures were all negative.Magnetic resonance imaging(MRI) of 11 cases was abnormal ; most lesions were bilateral symmetry.4 cases(41.6％) had one lesion.There were 6 patients with abnormal signal in basal ganglia,3 patients in the frontal lobe,5 patients in the brain stem,2 cases in cerebral peduncle,2 cases in midbrain and 3 cases in the occipital.Conclusion Severe viral encephalitis in children shows abnormal EEG which changes with the severity and development of the disease.