中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
8期
1191-1193
,共3页
康丽%马孝%杨义成%付敏%吴海斌
康麗%馬孝%楊義成%付敏%吳海斌
강려%마효%양의성%부민%오해빈
带状疱疹%康复新液%泛昔洛韦
帶狀皰疹%康複新液%汎昔洛韋
대상포진%강복신액%범석락위
Herpes zoster%Kangfuxin liqiud%Famciclovir
目的 探讨康复新液联合泛昔洛韦治疗带状疱疹的临床效果.方法 选取广州医科大学附属深圳沙井医院的89例带状疱疹患者,采用完全随机分组法将其分为观察组(46例)和对照组(43例).观察组给予康复新液10 ml口服,3次/d,联合泛昔洛韦0.25 g口服,3次/d治疗,对照组单独采用泛昔洛韦0.25 g口服,3次/d.2组疗程均为7d,观察2组总有效率,患者疼痛减轻时间、疼痛消失时间及皮疹干涸结痂时间、有无神经后遗痛及不良反应.结果 观察组7d时总有效率均高于对照组[84.8％(39/46)比62.8％(27/43)],差异有统计学意义(x2=5.61,P＜0.05).观察组疼痛减轻时间、疼痛消火时间及皮疹干涸结痂时间均明显短于对照组[(1.3±0.5)d比(3.4±1.2)d,(4.2±1.6)d比(6.3±1.5)d1,(6.5±1.9)d比(8.2±1.7)d],差异均有统计学意义(均P＜0.01).观察组患者未出现后遗神经痛及不良反应,对照组出现2例后遗神经痛,2例胃肠道不适.结论 康复新液联合泛昔洛韦治疗带状疱疹效果确切.
目的 探討康複新液聯閤汎昔洛韋治療帶狀皰疹的臨床效果.方法 選取廣州醫科大學附屬深圳沙井醫院的89例帶狀皰疹患者,採用完全隨機分組法將其分為觀察組(46例)和對照組(43例).觀察組給予康複新液10 ml口服,3次/d,聯閤汎昔洛韋0.25 g口服,3次/d治療,對照組單獨採用汎昔洛韋0.25 g口服,3次/d.2組療程均為7d,觀察2組總有效率,患者疼痛減輕時間、疼痛消失時間及皮疹榦涸結痂時間、有無神經後遺痛及不良反應.結果 觀察組7d時總有效率均高于對照組[84.8％(39/46)比62.8％(27/43)],差異有統計學意義(x2=5.61,P＜0.05).觀察組疼痛減輕時間、疼痛消火時間及皮疹榦涸結痂時間均明顯短于對照組[(1.3±0.5)d比(3.4±1.2)d,(4.2±1.6)d比(6.3±1.5)d1,(6.5±1.9)d比(8.2±1.7)d],差異均有統計學意義(均P＜0.01).觀察組患者未齣現後遺神經痛及不良反應,對照組齣現2例後遺神經痛,2例胃腸道不適.結論 康複新液聯閤汎昔洛韋治療帶狀皰疹效果確切.
목적 탐토강복신액연합범석락위치료대상포진적림상효과.방법 선취엄주의과대학부속심수사정의원적89례대상포진환자,채용완전수궤분조법장기분위관찰조(46례)화대조조(43례).관찰조급여강복신액10 ml구복,3차/d,연합범석락위0.25 g구복,3차/d치료,대조조단독채용범석락위0.25 g구복,3차/d.2조료정균위7d,관찰2조총유효솔,환자동통감경시간、동통소실시간급피진간학결가시간、유무신경후유통급불량반응.결과 관찰조7d시총유효솔균고우대조조[84.8％(39/46)비62.8％(27/43)],차이유통계학의의(x2=5.61,P＜0.05).관찰조동통감경시간、동통소화시간급피진간학결가시간균명현단우대조조[(1.3±0.5)d비(3.4±1.2)d,(4.2±1.6)d비(6.3±1.5)d1,(6.5±1.9)d비(8.2±1.7)d],차이균유통계학의의(균P＜0.01).관찰조환자미출현후유신경통급불량반응,대조조출현2례후유신경통,2례위장도불괄.결론 강복신액연합범석락위치료대상포진효과학절.
Objective To discuss the clinical effect of Kangfuxin liquid combined with famciclovir treating herpes zoster.Methods Eighty-nine patients with herpes zoster were randomly divided into observation group (46 cases) and control group (43 cases).The observation group was given Kangfuxin liqiud combined with famiciclovir,while the control group was given famciclovir.The course of treatment was seven days.The total effective rate,pain relief time,pain disappear time,scab in rash time,post-herpetic neuralgia and adverse reaction of two groups were observed.Results The total effective rate of observation group after treatment of 7 days was higher than that of control group [84.8％ (39/46) vs 62.8％ (27/43)],there were significant differences (x2 =5.61,P ＜ 0.05).The pain relief time,pain disappear time,scab in rash time in observation group were shorter than those in control group [(1.3±0.5)d vs (3.4 ±1.2)d,(4.2±1.6)d vs (6.3 ±l.5)d,(6.5±1.9)d vs (8.2 ±1.7)d] (P ＜ 0.01).There was no post-herpetic neuralgia and adverse reaction in observation group;there were 2 patients with post-herpetic neuralgia and 2 patients with gastrointestinal intolerance in control group.Conclusion Kangfuxin liqiud combined with famciclovir is a safe and effective method to treat the herps zoster.
