中华皮肤科杂志
中華皮膚科雜誌
중화피부과잡지
Chinese Journal of Dermatology
2011年
11期
786-788
,共3页
李凯%陈柳青%杨光艳%邢建军%宋玲娟%罗庆%白静峰%张良%曾宪玉%周小勇%段逸群
李凱%陳柳青%楊光豔%邢建軍%宋玲娟%囉慶%白靜峰%張良%曾憲玉%週小勇%段逸群
리개%진류청%양광염%형건군%송령연%라경%백정봉%장량%증헌옥%주소용%단일군
红皮病%预后
紅皮病%預後
홍피병%예후
Erythroderma%Prognosis
目的 探讨红皮病的病因与临床特征的相关性.方法 回顾性分析182例红皮病患者的临床资料.结果 男女之比为2.8∶1；发病年龄(58.6±14.6)岁.继发于原有皮肤病135例(74.2％),药物过敏14例(7.7％),恶性肿瘤8例(4.4％),原因不明25例(13.7％).红皮病诱发原因中系统用药诱发比例最高,共52例(28.6％),其中最常见的药物为糖皮质激素.随访76例,58例痊愈后未再发红皮病,再发患者14例,死亡5例,2例不明原因红皮病患者经过多次组织病理检查确诊为蕈样肉芽肿.结论 继发于原有皮肤病是红皮病的最常见原因.原因不明红皮病患者易复发,有伴随恶性肿瘤可能,应密切随访.
目的 探討紅皮病的病因與臨床特徵的相關性.方法 迴顧性分析182例紅皮病患者的臨床資料.結果 男女之比為2.8∶1；髮病年齡(58.6±14.6)歲.繼髮于原有皮膚病135例(74.2％),藥物過敏14例(7.7％),噁性腫瘤8例(4.4％),原因不明25例(13.7％).紅皮病誘髮原因中繫統用藥誘髮比例最高,共52例(28.6％),其中最常見的藥物為糖皮質激素.隨訪76例,58例痊愈後未再髮紅皮病,再髮患者14例,死亡5例,2例不明原因紅皮病患者經過多次組織病理檢查確診為蕈樣肉芽腫.結論 繼髮于原有皮膚病是紅皮病的最常見原因.原因不明紅皮病患者易複髮,有伴隨噁性腫瘤可能,應密切隨訪.
목적 탐토홍피병적병인여림상특정적상관성.방법 회고성분석182례홍피병환자적림상자료.결과 남녀지비위2.8∶1；발병년령(58.6±14.6)세.계발우원유피부병135례(74.2％),약물과민14례(7.7％),악성종류8례(4.4％),원인불명25례(13.7％).홍피병유발원인중계통용약유발비례최고,공52례(28.6％),기중최상견적약물위당피질격소.수방76례,58례전유후미재발홍피병,재발환자14례,사망5례,2례불명원인홍피병환자경과다차조직병리검사학진위심양육아종.결론 계발우원유피부병시홍피병적최상견원인.원인불명홍피병환자역복발,유반수악성종류가능,응밀절수방.
Objective To study the correlation between the etiology and clinical features of erythroderma.Methods The clinical data on 182 patients with erythroderma were retrospectively collected and analyzed.Results The male-to-female ratio was 2.8 ∶ 1 and the average age at onset was 58.6 ± 14.6 years.Of the 182 cases,135 (74.2％) were due to pre-existing dermatoses,14 (7.7％) to drug reaction,8 (4.4％) to malignancies,while 25 (13.7％) had no obvious precipitating factors.The most frequent triggering factor was systemic consumption of drugs (52 patients,28.6％ ),and glucocorticosteroid was the most prevalent causative drug.Seventy-six patients were followed up,recurrence was observed in 14 patients but not in 58 patients,and 5 patients died,2 patients with idiopathic erythroderma were finally diagnosed with mycosis fungoides (MF)after multiple skin biopsies.Conclusions Pre-existing dermatoses are the most frequent cause of erythroderma.Idiopathic erythroderma is liable to relapse,possibly associated with malignancies,and should be closely followed up.
