CAJ | 학술논문

目的回顾分析国内首例夫妻间配对交换捐肾肾移植的资料.方法 2006年4月2对夫妻进行了配对交换捐肾肾移植.受者1为男性,血型为O型；供者1为受者1的妻子,血型为A型.受者2为女性,血型为A型,曾接受过肾移植,移植肾功能衰竭后等待再次肾移植；供者2为受者2的丈夫,血型为O型.2对供、受者均在充分知情的情况下自愿同意与另一对进行交换配对肾移植.结果移植手术均顺利.受者1移植肾共计存活21个月,受者于移植后30个月时死亡.受者2移植肾存活30个月,受者于移植后31个月时死亡.供者手术后均健康存活.结论亲属配对交换捐肾肾移植的临床实施应该在严格的医学标准、伦理学标准以及明确的政策法规框架下进行.
목적 회고분석국내수례부처간배대교환연신신이식적자료.방법 2006년4월2대부처진행료배대교환연신신이식.수자1위남성,혈형위O형；공자1위수자1적처자,혈형위A형.수자2위녀성,혈형위A형,증접수과신이식,이식신공능쇠갈후등대재차신이식；공자2위수자2적장부,혈형위O형.2대공、수자균재충분지정적정황하자원동의여령일대진행교환배대신이식.결과 이식수술균순리.수자1이식신공계존활21개월,수자우이식후30개월시사망.수자2이식신존활30개월,수자우이식후31개월시사망.공자수술후균건강존활.결론 친속배대교환연신신이식적림상실시응해재엄격적의학표준、윤리학표준이급명학적정책법규광가하진행.
Objective To review the first case of paired-exchange kidney transplantation between two couples in China.Methods In April 2006,two cases of paired-exchange living kidney transplantations were successfully performed.Husband 1 in blood type O received a kidney donated from husband 2 in blood type O,while wife 2 in blood type A received a kidney from wife 1 in blood type A.Results The transplantation was performed smoothly.Renal graft in husband 1 functioned for 21 months,and the recipient died at 9th month due to infection.Graft survival and patient survival in wife 2 were 30 month and 31 month respectively.Conclusion Paired-exchange of living-related kidney donation and transplantation,as an effective pathway to resolve the shortage of organ,could be programmed with cautious medical guideline,ethical consideration and legal framework in China.