CAJ | 학술논문

目的通过六分钟步行试验(6MWT),探讨抑郁对慢性阻塞性肺疾病(COPD)患者运动能力的影响.方法 2009年9月至2011年4月,选择急性发作症状得到控制的COPD患者120例,根据汉密尔顿抑郁量表(HAMD)评分分组,其中HAMD评分＜7分者48例,为正常对照组；HAMD评分≥17分者60例,为抑郁组；7分≤HAMD评分＜17分为不确定患者是否抑郁,不纳入研究范同.入组患者进行6MWT,试验前后测定患者的血压、心率、呼吸频率、呼吸困难和疲劳评分(Borg指数)及血气分析,所有患者均测定BMI和肺功能.结果抑郁组和正常对照组6MWT距离分别为(259±91)m和(312±71)m,抑郁组步行距离短(t=3.31,P＜0.01).抑郁组6MWT后心率、收缩压、呼吸频率、Borg指数分别为(108.2±11.3)次/min、(149±15)mm Hg(1 mm Hg=0.133 kPa)、(23.3±3.9)次/min、(4.65±1.67)分,正常对照组分别为(95±9)次/min、(142 ±9) mm Hg、(20.2±3.7)次/min、(2.59±1.52)分,两组比较差异有统计学意义(t值分别为6.44、2.76、4.20和6.33,均P＜0.01).结论抑郁可影响COPD患者的运动能力,治疗时不仅要关注疾病本身,同时也应关注患者心理状态对疾病的影响.
목적 통과륙분종보행시험(6MWT),탐토억욱대만성조새성폐질병(COPD)환자운동능력적영향.방법 2009년9월지2011년4월,선택급성발작증상득도공제적COPD환자120례,근거한밀이돈억욱량표(HAMD)평분분조,기중HAMD평분＜7분자48례,위정상대조조；HAMD평분≥17분자60례,위억욱조；7분≤HAMD평분＜17분위불학정환자시부억욱,불납입연구범동.입조환자진행6MWT,시험전후측정환자적혈압、심솔、호흡빈솔、호흡곤난화피로평분(Borg지수)급혈기분석,소유환자균측정BMI화폐공능.결과 억욱조화정상대조조6MWT거리분별위(259±91)m화(312±71)m,억욱조보행거리단(t=3.31,P＜0.01).억욱조6MWT후심솔、수축압、호흡빈솔、Borg지수분별위(108.2±11.3)차/min、(149±15)mm Hg(1 mm Hg=0.133 kPa)、(23.3±3.9)차/min、(4.65±1.67)분,정상대조조분별위(95±9)차/min、(142 ±9) mm Hg、(20.2±3.7)차/min、(2.59±1.52)분,량조비교차이유통계학의의(t치분별위6.44、2.76、4.20화6.33,균P＜0.01).결론 억욱가영향COPD환자적운동능력,치료시불부요관주질병본신,동시야응관주환자심리상태대질병적영향.
Objective To investigate the influences of depression on exercise capacity of patients with chronic obstructive pulmonary disease (COPD) in 6-minute walk test (6MWT).Methods One hundred and twenty COPD patients,whose acute exacerbation was controlled,were enrolled in the study from September 2009 to April 2011.According to Hamilton depression scale (HAMD) scores,48 patients with HAMD scores ＜ 7 were classified as non-depression group (control),60 patients with HAMD scores ≥17 were classified as depression group,patients with 7 ≤ HAMD scores ＜ 17 were classified as uncertain depression and not included in the experiment.Six-minute walk testing was performed in patients.Blood pressure,heart rates,respiratory rates,Borg scores were measured before and after 6MWT; body mass index and lung function were also measured in all patients.Results The distances of walk in the depression group and control group were (259 ±91) and (312 ±71) meters,respectively (P ＜0.05).Heart rates,svstolic blood pressure,respiratory rates and Borg index in depression group after testing were (108± 11)/min,(148.7 ± 15.4) mm Hg(1 mm Hg =0.133 kPa),(23.3 ±3.9) /min and (4.65 ± 1.67),respectively;those for control group were (95 ±9) /min,(141.8±8.9) mm Hg,(20.2 ±3.7) /min and (2.59±1.52),respectively.There were significant differences between two groups (all P ＜ 0.05).Conclusions Depression may affect the exercise capacity of COPD patients,the psychological status of the patients should be under consideration when conventional treatment is taken.