CAJ | 학술논문

应用ELISA和电化学发光法联合监测150例小细胞肺癌患者治疗前后及复发转移前胃泌素前体释放肽片段和神经元特异性烯醇化酶.随访1年显示,患者血清胃泌素前体释放肽片段和神经元特异性烯醇化酶水平与疗效呈负相关、与病情发展呈正相关,差异均有统计学意义(P＜0.05).胃泌素前体释放肽片段和神经元特异性烯醇化酶水平能够反映小细胞肺癌患者病情变化并疗效评估.
응용ELISA화전화학발광법연합감측150례소세포폐암환자치료전후급복발전이전위비소전체석방태편단화신경원특이성희순화매.수방1년현시,환자혈청위비소전체석방태편단화신경원특이성희순화매수평여료효정부상관、여병정발전정정상관,차이균유통계학의의(P＜0.05).위비소전체석방태편단화신경원특이성희순화매수평능구반영소세포폐암환자병정변화병료효평고.
Before and after treatment as well as before metastasis,the combined detection of progastrin-releasing peptide (ProGRP) and neuron-specific enolase (NSE) was performed in 150 patients with small cell lung cancer.The follow-up period was 1 year.Enzyme-linked immunosorbent assay (ELISA) and electrochemiluminescence immunoassay were conducted.The result showed a negative correlation between the serum levels of ProGRP and NSE the curative effect.And a positive correlation existed between the serum levels of ProGRP and NSE and disease development.The difference had statistical significance (P ＜ 0.05).The levels of ProGRP and NSE may be used to indicate the disease development and evaluate the curative effect.