中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2014年
4期
250-253
,共4页
陈哲萌%郭谊%王爽%汤业磊%葛叶波%丁美萍
陳哲萌%郭誼%王爽%湯業磊%葛葉波%丁美萍
진철맹%곽의%왕상%탕업뢰%갈협파%정미평
癫痫%自杀%抑郁症%危险因素%简明精神病状态评定量表
癲癇%自殺%抑鬱癥%危險因素%簡明精神病狀態評定量錶
전간%자살%억욱증%위험인소%간명정신병상태평정량표
Epilepsy%Suicide%Depressive disorder%Risk factors%Brief psychiatric rating scale
目的 研究成人癫痫患者自杀风险及其相关危险因素.方法 采用简明国际神经精神访谈(MINI)自杀风险模块和抑郁障碍模块对211例浙江大学医学院附属第二医院癫痫门诊的成年癫痫患者进行心理评估,并详细记录患者的年龄、性别、就业状况、婚姻、教育年限、发病年龄、病程、发作类型、发作频率、头颅MRI结果以及使用抗癫痫药种数,比较有或无自杀风险患者上述相关因素的差异以及抑郁障碍与自杀风险的关系.结果 本组病例中有自杀风险的患者占21.3％(45/211),伴有抑郁障碍的患者占17.1％(36/211)；而伴有抑郁障碍患者的自杀风险高达75.0％(27/36),非抑郁障碍患者的自杀风险达10.3％(18/175),其差异有统计学意义(x2=74.525,P＜0.01).存在自杀风险的患者有60.0％ (27/45)伴发抑郁障碍,自杀风险等级高者伴发抑郁障碍的概率越高,不同自杀风险组间抑郁障碍率比较差异有统计学意义.结论 癫痫患者存在自杀风险,伴有抑郁障碍的癫痫患者自杀风险更高.
目的 研究成人癲癇患者自殺風險及其相關危險因素.方法 採用簡明國際神經精神訪談(MINI)自殺風險模塊和抑鬱障礙模塊對211例浙江大學醫學院附屬第二醫院癲癇門診的成年癲癇患者進行心理評估,併詳細記錄患者的年齡、性彆、就業狀況、婚姻、教育年限、髮病年齡、病程、髮作類型、髮作頻率、頭顱MRI結果以及使用抗癲癇藥種數,比較有或無自殺風險患者上述相關因素的差異以及抑鬱障礙與自殺風險的關繫.結果 本組病例中有自殺風險的患者佔21.3％(45/211),伴有抑鬱障礙的患者佔17.1％(36/211)；而伴有抑鬱障礙患者的自殺風險高達75.0％(27/36),非抑鬱障礙患者的自殺風險達10.3％(18/175),其差異有統計學意義(x2=74.525,P＜0.01).存在自殺風險的患者有60.0％ (27/45)伴髮抑鬱障礙,自殺風險等級高者伴髮抑鬱障礙的概率越高,不同自殺風險組間抑鬱障礙率比較差異有統計學意義.結論 癲癇患者存在自殺風險,伴有抑鬱障礙的癲癇患者自殺風險更高.
목적 연구성인전간환자자살풍험급기상관위험인소.방법 채용간명국제신경정신방담(MINI)자살풍험모괴화억욱장애모괴대211례절강대학의학원부속제이의원전간문진적성년전간환자진행심리평고,병상세기록환자적년령、성별、취업상황、혼인、교육년한、발병년령、병정、발작류형、발작빈솔、두로MRI결과이급사용항전간약충수,비교유혹무자살풍험환자상술상관인소적차이이급억욱장애여자살풍험적관계.결과 본조병례중유자살풍험적환자점21.3％(45/211),반유억욱장애적환자점17.1％(36/211)；이반유억욱장애환자적자살풍험고체75.0％(27/36),비억욱장애환자적자살풍험체10.3％(18/175),기차이유통계학의의(x2=74.525,P＜0.01).존재자살풍험적환자유60.0％ (27/45)반발억욱장애,자살풍험등급고자반발억욱장애적개솔월고,불동자살풍험조간억욱장애솔비교차이유통계학의의.결론 전간환자존재자살풍험,반유억욱장애적전간환자자살풍험경고.
Objective To investigate the relationships of suicide risk and its associated risk factors in adult patients with epilepsy.Methods All 211 adult patients with epilepsy from the epilepsy clinic of the Second Affiliated Hospital,Zhejiang University School of Medicine,were enrolled to evaluate the presence of suicide risk and depressive disorder by using the suicide module and the depressive disorder module of the Mini International Neuropsychiatric Interview (MINI).Demographic variables for age,gender,employment status,marital status,years of education,and seizure factors for age of onset,types of seizure,seizure frequency and epilepsy duration,result of MRI and types of antiepileptic drugs were also recorded.We compared the differences of risk factors between the two groups with or without suicide risk and investigated the relationships between the depressive disorder and suicide risk.Results The suicide risk of the patients was 21.3％ (45/211),and 17.1％ (36/211) of the patients had depressive disorder.The suicide risk of the epilepsy patients associated with depressive disorder was 75.0％ (27/36),and the suicide risk of the epilepsy patients associated with no depressive disorder was 10.3％ (18/175).There was statistical difference between the two groups (x2 =74.525,P ＜ 0.01).About 60.0％ (27/45) of the patients with suicide risk was accompanied with depressive disorder.As suicide risk increased,the proportion of concurrent depressive disorder elevated.There was significant statistical difference in the rates of depressive disorder among the different suicide risk groups.Conclusions The patients with epilepsy have suicide risk.The suicide risk is higher in patients with depressive disorder.
