中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2014年
7期
482-486
,共5页
布鲁杆菌病%中枢神经系统细菌感染%磁共振成像%回顾性研究
佈魯桿菌病%中樞神經繫統細菌感染%磁共振成像%迴顧性研究
포로간균병%중추신경계통세균감염%자공진성상%회고성연구
Brucellosis%Central nervous system bacterial infections%Magnetic resonance imaging%Retrospective studies
目的 探讨神经型布氏杆菌病(NB)患者的临床症状、实验室检查、影像学表现等临床特点,以提高对本病的认识.方法 对我院2002年1月至2013年5月收治的7例NB患者进行回顾性分析.结果 男女发病比例为6∶1,平均发病年龄为46岁.以脑血管病起病者1例,以中枢神经系统感染起病者5例,以脊髓炎起病者1例.血清凝集试验阳性6例,血培养阳性1例.影像学病灶位于双大脑半球皮质、皮质下、基底节等部位者2例,位于额叶者4例,位于胸髓者1例,位于双侧小脑、脑桥等部位者1例.经敏感抗生素治疗,1例死亡,6例好转.结论 NB是布氏杆菌病的少见类型,临床表现缺乏特异性,影像学及血清学检测是确诊的重要手段,经正规治疗后预后良好.深入认识本病,早期诊断和早期治疗很有价值.
目的 探討神經型佈氏桿菌病(NB)患者的臨床癥狀、實驗室檢查、影像學錶現等臨床特點,以提高對本病的認識.方法 對我院2002年1月至2013年5月收治的7例NB患者進行迴顧性分析.結果 男女髮病比例為6∶1,平均髮病年齡為46歲.以腦血管病起病者1例,以中樞神經繫統感染起病者5例,以脊髓炎起病者1例.血清凝集試驗暘性6例,血培養暘性1例.影像學病竈位于雙大腦半毬皮質、皮質下、基底節等部位者2例,位于額葉者4例,位于胸髓者1例,位于雙側小腦、腦橋等部位者1例.經敏感抗生素治療,1例死亡,6例好轉.結論 NB是佈氏桿菌病的少見類型,臨床錶現缺乏特異性,影像學及血清學檢測是確診的重要手段,經正規治療後預後良好.深入認識本病,早期診斷和早期治療很有價值.
목적 탐토신경형포씨간균병(NB)환자적림상증상、실험실검사、영상학표현등림상특점,이제고대본병적인식.방법 대아원2002년1월지2013년5월수치적7례NB환자진행회고성분석.결과 남녀발병비례위6∶1,평균발병년령위46세.이뇌혈관병기병자1례,이중추신경계통감염기병자5례,이척수염기병자1례.혈청응집시험양성6례,혈배양양성1례.영상학병조위우쌍대뇌반구피질、피질하、기저절등부위자2례,위우액협자4례,위우흉수자1례,위우쌍측소뇌、뇌교등부위자1례.경민감항생소치료,1례사망,6례호전.결론 NB시포씨간균병적소견류형,림상표현결핍특이성,영상학급혈청학검측시학진적중요수단,경정규치료후예후량호.심입인식본병,조기진단화조기치료흔유개치.
Objective To explore the clinical features,laboratory tests,imaging characteristics of neurobrucellosis,and to improve the understanding of the disease.Methods A retrospective analysis was performed in seven patients with neurobrucellosis in our hospital from January 2002 to May 2013.Results The proportion of men and women was 6∶ 1,and the average age was 46 years.One case was attacked with the symptoms of cerebrovascular disease,another one with the symptoms of myelitis,and the other five with the symptoms of meningoencephalitis.Six had positive results of serum agglutination test,and the other one had a positive result of blood culture instead.Imaging findings lacked of specificity.There were two patients whose lesions were in the hemisphere cortex,subcortical,basal ganglia and other parts,four patients whose lesions were in the frontal lobe,one in the chest pulp,and one in both sides of cerebellum and pons.After systematical treatment,one case died,the other 6 cases recovered,and no one relapsed or got functional disability during the one-year follow-up.Conclusions Neurobrucellosis is a rare type of brucellosis,and its clinical manifestations lack of specificity,and imaging and serological detections are important for diagnosis.It is beneficial for patients if diagnosed early and treated systematically,so good understanding of this disease,early diagnosis and treatment are of great value.
