CAJ | 학술논문

目的探讨Sturge-Weber综合征继发癫痫和发育迟滞的手术治疗的方法和疗效.方法回顾性分析2007年11月手术治疗的Sturge-Webet综合征继发癫痫和智力、体格等多方面发育迟滞的1例患儿的临床资料.进行术前评估后,在全麻下行"右侧半球开颅,右侧额、顶叶和部分颞、枕叶脑组织皮层切除术".结果术后当天患儿左侧肢体肌力为Ⅰ级,但3 d后左侧肢体肌力开始逐渐恢复,至术后21 d,左侧肢体肌力恢复至术前水平.随访18个月,患儿癫痫发作完全消失,并于术后12个月时自行停用抗癫痫药物.左侧肢体肌力达到Ⅴ-级,功能好于术前,左手手指活动好转,能握住钢笔等物体.语言功能显著好转.攻击行为消失,性格较温顺,认知和行为能力均有明显好转.发育状况评估DQ值从术前的48改善为75.结论 Sturge-Weber综合征继发癫痫和发育迟滞可行病变多脑叶切除性手术治疗,不仅可以控制癫痫,还可能改善发育.
목적 탐토Sturge-Weber종합정계발전간화발육지체적수술치료적방법화료효.방법 회고성분석2007년11월수술치료적Sturge-Webet종합정계발전간화지력、체격등다방면발육지체적1례환인적림상자료.진행술전평고후,재전마하행"우측반구개로,우측액、정협화부분섭、침협뇌조직피층절제술".결과 술후당천환인좌측지체기력위Ⅰ급,단3 d후좌측지체기력개시축점회복,지술후21 d,좌측지체기력회복지술전수평.수방18개월,환인전간발작완전소실,병우술후12개월시자행정용항전간약물.좌측지체기력체도Ⅴ-급,공능호우술전,좌수수지활동호전,능악주강필등물체.어언공능현저호전.공격행위소실,성격교온순,인지화행위능력균유명현호전.발육상황평고DQ치종술전적48개선위75.결론 Sturge-Weber종합정계발전간화발육지체가행병변다뇌협절제성수술치료,불부가이공제전간,환가능개선발육.
Objective To explore the strategy and its effect of surgical treatment of epilepsy and development retardation due to Sturge-Weber syndrome.Methods The clinical data of an infant surgically treated for epilepsy,mental and physical development retardation due to Sturge-Weber syndrome were retrospectively reviewed.After sufficient preoperative evaluation,the operation was performed through the hemisphere craniectomy,and the right total parietal lobe,partial frontal temporal and occipital lobes were removed.Results The muscle force of left limbs was grade I post operation,but they recovered gradually after 3 days,and recovered to preoperative level after 3 weeks.During the 18 months interval of follow-up the patient was seizure free,her muscle force of right upper limb improved to grade V-,left fingers movement improved significantly,aggressive behaviour disappeared,and DQ improved from preoperative 48 to 75.Conclusion Epilepsy and development retardation due to Sturge-Weber syndrome can be treated by resection the cortex of involved multiple brain lobes.