中华神经外科杂志
中華神經外科雜誌
중화신경외과잡지
Chinese Journal of Neurosurgery
2012年
12期
1196-1200
,共5页
邱天明%吴劲松%庄冬晓%姚成军%路俊锋%朱凤平%章捷%龚秀%毛颖%周良辅
邱天明%吳勁鬆%莊鼕曉%姚成軍%路俊鋒%硃鳳平%章捷%龔秀%毛穎%週良輔
구천명%오경송%장동효%요성군%로준봉%주봉평%장첩%공수%모영%주량보
静态功能磁共振%语言区%神经胶质瘤
靜態功能磁共振%語言區%神經膠質瘤
정태공능자공진%어언구%신경효질류
Resting-state fMRI%Language area%Glioma
目的 探讨静态功能磁共振(rsfMRI)分析方法在脑胶质瘤术前语言皮质定位中的应用价值.方法 12例主侧半球脑胶质瘤患者行术前rsfMRI,结合语言任务态血氧饱和依赖功能磁共振成像(BOLD fMRI)定位脑语言皮质,采用唤醒开颅结合术中皮质电刺激验证rsfMRI定位语言皮质的敏感性.结果 12例成功行rsfMRI扫描,10例配合完成语言BOLD fMRI扫描.12例唤醒开颅成功,每例各定位1～7个皮质语言阳性位点,共46个.其中22个语言阳性位点在rsfMRI上显示,其显示语言区的敏感度为47.8％(22/46,12例),13个语言阳性位点在语言BOLD fMRI上表现为激活,敏感度为35.1％(13/37,10例).结论 rsfMRI有助于脑胶质瘤术前语言区定位,但其敏感性有待提高.
目的 探討靜態功能磁共振(rsfMRI)分析方法在腦膠質瘤術前語言皮質定位中的應用價值.方法 12例主側半毬腦膠質瘤患者行術前rsfMRI,結閤語言任務態血氧飽和依賴功能磁共振成像(BOLD fMRI)定位腦語言皮質,採用喚醒開顱結閤術中皮質電刺激驗證rsfMRI定位語言皮質的敏感性.結果 12例成功行rsfMRI掃描,10例配閤完成語言BOLD fMRI掃描.12例喚醒開顱成功,每例各定位1～7箇皮質語言暘性位點,共46箇.其中22箇語言暘性位點在rsfMRI上顯示,其顯示語言區的敏感度為47.8％(22/46,12例),13箇語言暘性位點在語言BOLD fMRI上錶現為激活,敏感度為35.1％(13/37,10例).結論 rsfMRI有助于腦膠質瘤術前語言區定位,但其敏感性有待提高.
목적 탐토정태공능자공진(rsfMRI)분석방법재뇌효질류술전어언피질정위중적응용개치.방법 12례주측반구뇌효질류환자행술전rsfMRI,결합어언임무태혈양포화의뢰공능자공진성상(BOLD fMRI)정위뇌어언피질,채용환성개로결합술중피질전자격험증rsfMRI정위어언피질적민감성.결과 12례성공행rsfMRI소묘,10례배합완성어언BOLD fMRI소묘.12례환성개로성공,매례각정위1～7개피질어언양성위점,공46개.기중22개어언양성위점재rsfMRI상현시,기현시어언구적민감도위47.8％(22/46,12례),13개어언양성위점재어언BOLD fMRI상표현위격활,민감도위35.1％(13/37,10례).결론 rsfMRI유조우뇌효질류술전어언구정위,단기민감성유대제고.
Objective To introduce the application of resting-state functional magnetic resonance imaging (rsfMRI) in the preoperative localizing language area of glioma patients.Methods 12 patients with gliomas involved in the language area underwent rsfMRI and BOLD of language.Both rsfMRI and BOLD of language were utilized to localize language areas in awake surgery and verified by direct cortical stimulation (DCS).Results 12 patients performed rsfMRI successfully; meanwhile,10 patients accomplished the acquisition of BOLD of language because two patients were unable to cooperate well with the language task in scanning.In total,46 positive points were found by DCS in 12 awake surgeries,which indicated that the sensitivity of rsfMRI in revealing the language area was 47.8％ (22/46,12 cases),and the sensitivity of BOLD of language was 35.1％ (13/37,10 cases).Conclusions RsfMRI may be utilized as one of the valuable tools,to some extent,in localizing the language area before glioma surgery and its sensitivity should be improved.
