CAJ | 학술논문

目的探讨儿童脑积水第三脑室底造瘘术后脑认知功能变化情况.方法回顾分析儿童脑积水43例,其中行第三脑室底造瘘术20例(手术组),对手术前后的CT/MRI、脑电图、SPECT、发育商DQ进行对比,评价术后患儿脑认知功能康复的情况.未行手术23例(未手术组),出院后正常育儿,于诊断后2周、2个月、6个月行发育商(DQ)测定.结果手术组术后2周与术前及未手术组比较发育商差异无统计学意义(P＞0.05),手术组术后2个月、6个月与未手术组比较发育商差异有统计学意义(P＜0.05),手术组术后2个月、6个月与术前相比发育商有统计学意义(P＜0.01).手术组术后发育商(DQ)值呈上升趋势改变(P＜0.01),术后脑室大小较术前变化不明显,脑电图异常率、SPECT脑血流灌注显像与术前相比差异均有统计学意义(P＜0.01).结论儿童脑积水行第三脑室底造瘘术可使脑认知功能改善,术后脑室大小的变化不明显.
목적 탐토인동뇌적수제삼뇌실저조루술후뇌인지공능변화정황.방법 회고분석인동뇌적수43례,기중행제삼뇌실저조루술20례(수술조),대수술전후적CT/MRI、뇌전도、SPECT、발육상DQ진행대비,평개술후환인뇌인지공능강복적정황.미행수술23례(미수술조),출원후정상육인,우진단후2주、2개월、6개월행발육상(DQ)측정.결과 수술조술후2주여술전급미수술조비교발육상차이무통계학의의(P＞0.05),수술조술후2개월、6개월여미수술조비교발육상차이유통계학의의(P＜0.05),수술조술후2개월、6개월여술전상비발육상유통계학의의(P＜0.01).수술조술후발육상(DQ)치정상승추세개변(P＜0.01),술후뇌실대소교술전변화불명현,뇌전도이상솔、SPECT뇌혈류관주현상여술전상비차이균유통계학의의(P＜0.01).결론 인동뇌적수행제삼뇌실저조루술가사뇌인지공능개선,술후뇌실대소적변화불명현.
Objective To research the children's neurocognitive function changes after third ventriculostomy of hydrocephalus.Methods We retrospectively analyzed the medical files of 43 cases of children with hydrocephalus,including the endoscopic third ventriculostomy of 20 cases (Operation Group).The data regarding CT/MRI,EEG,SPECT,developmental quotient (DQ) before and after surgery were studied.We eveluated the children neurocognitive function recovery time and degree effect in postoperative stage.Surgery was not done in 23 cases (without operation group),in which developmental quotient (DQ)is measured after two weeks,2 month and 6 months of the diagnosis.Results The two groups after 2 month and 6 months of operation were compared developmental quotient difference were significant (P ＜ 0.05).In operation group:2 month and 6 months after operation compared with the preoperative developmental quotient difference were significant (P ＜ 0.01),operation group developmental quotient (DQ) value showed ascendant trend change (P ＜ 0.01).Comparing with the preoperative.postoperative ventricle size did not change significantly.The EEG abnormal rate,ECT cerebral blood perfusion imaging comparing with preoperative difference were significant (P ＜ 0.01),with a statistical significance.Conclusions Children after ETV can make neurocognitive function recovery,postoperative ventricular size change and improve is not obvious.