CAJ | 학술논문

目的总结分析经皮椎体成形术(PVP)在骨质疏松性椎体压缩骨折及椎体肿瘤治疗中临床应用的疗效.方法宣武医院神经外科2007年1月至2012年6月应用PVP治疗45例患者共62个病变椎体,随访时间点为术后24h、3、6、12、24及36个月,采用VAS、ODI评价其临床疗效,椎体前缘高度及Cobb角评估影像学结果.结果平均随访时间(13.9±7.8)个月,术后24 h,患者VAS疼痛评分、ODI指数及Cobb角分别由术前(7.3±1.9)分、32.0±3.4和15.0°±2.3°降至术后(4.8±1.6)分、22.1±2.1和14.0°±1.9°(P＜0.05),椎体前缘高度由术前(16.0±1.8) mm升至(19.0±2.1)mm(P＜0.05).3～36个月随访期内,VAS评分、椎体前缘高度及Cobb角差异无统计学意义(P＞0.05).随访中约54％患者VAS评分维持在5分以内.结论 PVP是治疗骨折及肿瘤所致的椎体源性疼痛简单有效的微创疗法,临床疗效稳定.
목적 총결분석경피추체성형술(PVP)재골질소송성추체압축골절급추체종류치료중림상응용적료효.방법 선무의원신경외과2007년1월지2012년6월응용PVP치료45례환자공62개병변추체,수방시간점위술후24h、3、6、12、24급36개월,채용VAS、ODI평개기림상료효,추체전연고도급Cobb각평고영상학결과.결과 평균수방시간(13.9±7.8)개월,술후24 h,환자VAS동통평분、ODI지수급Cobb각분별유술전(7.3±1.9)분、32.0±3.4화15.0°±2.3°강지술후(4.8±1.6)분、22.1±2.1화14.0°±1.9°(P＜0.05),추체전연고도유술전(16.0±1.8) mm승지(19.0±2.1)mm(P＜0.05).3～36개월수방기내,VAS평분、추체전연고도급Cobb각차이무통계학의의(P＞0.05).수방중약54％환자VAS평분유지재5분이내.결론 PVP시치료골절급종류소치적추체원성동통간단유효적미창요법,림상료효은정.
Objective To assess the clinical and radiographic outcome of patients who underwent percutaneous vertebroplasty (PVP) in osteoporotic compression fractures and vertebral tumor.Methods Between January 2007 and June 2012,45 patients were treated with PVP at neurosurgery department of Xuanwu hospital; it were analyzed that the clinical and radiologic outcome including cement feature.The patient's clinic outcome was assessed before operation and 24 hours,3,6,12,24,36 months after the operation using visual analogue scale (VAS) and Oswestry disability index (ODI).The anterior vertebral body height and local sagittal Cobb's angle were also measured.Results The mean follow-up period was 13.917.8 months.Postoperative VAS,ODI,the local sagittal Cobb angle decreased from 7.3 ± 1.9,32.0±3.4 and 15.0° ±2.3° to4.8 ±1.6,22.1 t2.1 and 14.0° ±1.9° respectively before and after surgery (P ＜0.05).The anterior vertebral height increased from(16.0 ± 1.8) mm to(19.0 ± 2.1) mm before and after surgery (P ＜ 0.05).There are no significant changes in VAS,ODI,anterior vertebral body height and the local sagittal Cobb's angle during 3-36 months follow-up.54％ patients maintained with decreased VAS within 5 during follow-up.Conclusion PVP is an efficient miniinvasive procedure,which can provide durable pain relief in patients with osteoporotic compression fractures and vertebral tumor.