CAJ | 학술논문

目的对比分析PET-CT多显像剂检查与MRI在胶质瘤诊断的临床应用价值.方法回顾分析初诊疑为胶质瘤患者52例,以病理学结果为金标准分析PET-CT检查及MRI检查在胶质瘤诊断的临床应用价值.结果 32例患者经病理证实为胶质瘤；PET-CT检查出现2例假阳性,2例假阴性；MRI检查出现4例假阳性,13例假阴性；两者之间有统计学意义(McNemar检验,P =0.007 ＜0.05).PET-CT多显像剂显像在胶质瘤诊断灵敏度为94％(30/32),特异性为90％(18/20),准确率为92％ (48/52)；MRI检查诊断的灵敏度为59％ (19/32),特异性为80％ (16/20),准确率为67％ (35/52).结论 PET-CT多显像剂显像在胶质瘤诊断的灵敏度、特异性及准确率均显著高于MRI检查,在颅内胶质瘤诊断中有一定的优势.
목적 대비분석PET-CT다현상제검사여MRI재효질류진단적림상응용개치.방법 회고분석초진의위효질류환자52례,이병이학결과위금표준분석PET-CT검사급MRI검사재효질류진단적림상응용개치.결과 32례환자경병리증실위효질류；PET-CT검사출현2례가양성,2례가음성；MRI검사출현4례가양성,13례가음성；량자지간유통계학의의(McNemar검험,P =0.007 ＜0.05).PET-CT다현상제현상재효질류진단령민도위94％(30/32),특이성위90％(18/20),준학솔위92％ (48/52)；MRI검사진단적령민도위59％ (19/32),특이성위80％ (16/20),준학솔위67％ (35/52).결론 PET-CT다현상제현상재효질류진단적령민도、특이성급준학솔균현저고우MRI검사,재로내효질류진단중유일정적우세.
Objective To compare the diagnostic value of PET-CT and MRI in diagnosing of gliomas.Methods To compare the sensitivity and specificity of PET-CT with 18F-FDG and 13N-NH3/11 C-MET with MRI,the results of MRI and PET-CT imaging of 52 patients with suspicious gliomas were retrospectively reviewed.All cases were confirmed by operation and histopathology.Results Among the 52 cases,32 patients were verified with glioma.In PET-CT imaging there were only 2 false positive cases and 2 false negative cases.In contrast MRI produced 4 false positive cases and 13 false negative cases.The occurrence ratio is significantly different between these two entities (McNemar test,x2 =104,P =0.007 ＜0.05).PET-CT displayed sensitivity 94％ (30/32),specificity 90％ (18/20),and accuracy 92％ (48/52)in the diagnosis of gliomas.But MRI had the sensitivity 59％ (19/32),specificity 80％ (16/20),and accuracy 67％ (35/52).Conclusions Compared with MRI,PET-CT with 18F-FDG and 13 N-NH3/11 C-MET were demonstrated with higher sensitivity,specificity and accuracy than MRI,and would have more advantages in the diagnoses of intracranial gliomas.