CAJ | 학술논문

目的利用认知神经科学试验手段,采用疼痛共情功能测试范例,结合一般情感及人格特征评估,研究局限性岛叶胶质瘤对高级认知功能的影响.方法对5例单纯岛叶胶质瘤术前患者及18例健康成人对照进行疼痛共情功能及一般人格测试,采用非参数自助法检验,比较两组人群高级认知功能的差异.结果岛叶胶质瘤患者的疼痛共情功能明显低于健康对照组(P＜0.05),同时一般人格特质及情感没有出现明显变化(P＞0.05).结论岛叶涉及多种高级神经认知功能,尤其在疼痛共情的产生中发挥重要作用,岛叶胶质瘤会引起该功能的显著减退,但对于基本情感及人格没有影响.
목적 이용인지신경과학시험수단,채용동통공정공능측시범례,결합일반정감급인격특정평고,연구국한성도협효질류대고급인지공능적영향.방법 대5례단순도협효질류술전환자급18례건강성인대조진행동통공정공능급일반인격측시,채용비삼수자조법검험,비교량조인군고급인지공능적차이.결과 도협효질류환자적동통공정공능명현저우건강대조조(P＜0.05),동시일반인격특질급정감몰유출현명현변화(P＞0.05).결론 도협섭급다충고급신경인지공능,우기재동통공정적산생중발휘중요작용,도협효질류회인기해공능적현저감퇴,단대우기본정감급인격몰유영향.
Objective To investigate the influence of focal insular glioma to high-level cognitive function by adopting the Empathy of other's Pain (EOP) task followed the experimental methods in cognitive neuroscience and combined with the assessments of general emotional and personalitie feature.Methods Examing the empathy of pain and general personalities among five patients with focal insular glioma before operation and 18 healthy people as control group,compare the variation on advanced cognitivefunction between the two groups by the nonparametric bootstrapping method.Results By contrast with normal control group,deficits in both explicit and implicit empathetic pain processing were found in patients (P ＜ 0.05),although there is no significant difference of general personality feature and emotion between the two groups (P ＞ 0.05).Conclusions The insular lobe is related to a variety of advanced neurocognitive functions,especially plays an essential role of empathic pain processing.The insular glioma would lead to a significantly decline in this function but with little influence on general emotion and personalities.