CAJ | 학술논문

目的探讨神经外科患者全麻术后恢复期恶心呕吐(PONY)的发生情况及其危险因素.方法择期行神经外科手术的7 843例患者进行围术期变量的单因素比较和多因素Logistic回归分析,筛选发生PONV的危险因素.结果 1 176例患者全麻恢复期发生PONV,发生率为15％.Logistic回归分析提示女性、幕下肿瘤、长时间手术、术后中重度疼痛是发生PONV的危险因素;预防性使用抗呕吐药物、全凭静脉麻醉为保护因素(P＜0.05).结论神经外科患者女性、幕下肿瘤、长时间手术、术后中重度疼痛是麻醉恢复期PONV的危险因素;预防性使用抗呕吐药物、全凭静脉麻醉可以减少PONV的发生.
목적 탐토신경외과환자전마술후회복기악심구토(PONY)적발생정황급기위험인소.방법 택기행신경외과수술적7 843례환자진행위술기변량적단인소비교화다인소Logistic회귀분석,사선발생PONV적위험인소.결과 1 176례환자전마회복기발생PONV,발생솔위15％.Logistic회귀분석제시녀성、막하종류、장시간수술、술후중중도동통시발생PONV적위험인소;예방성사용항구토약물、전빙정맥마취위보호인소(P＜0.05).결론 신경외과환자녀성、막하종류、장시간수술、술후중중도동통시마취회복기PONV적위험인소;예방성사용항구토약물、전빙정맥마취가이감소PONV적발생.
Objective To investigate the incidence and risk factors for postoperative nausea and vomiting (PONV) following neurosurgical anesthesia.Methods 7 843 patients undergoing elective neurosurgery were included in this study.Patients' perioperative informations were recorded.Univariate and multivariate logistic regression was used to analyze the risk factors for PONV.Results PONV developed in 1 176 patients within 3 h following neurosurgery and the incidence was 15％.The logistic regression analysis indicated that the risk factors for PONV included female sex,infratentorial craniotomy,longer duration of surgery and postoperative median to severe pain.5-HT3 receptor antagonists prophylaxis and total intravenous anesthesia (TIVA) were protective factors (P ＜ 0.05).Conclusions Female sex,infratentorial craniotomy,longer duration of surgery and postoperative median to severe pain were predictors of PONV.5-HT3 receptor antagonists prophylaxis or TIVA will decrease the incidence of PONV.