中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2013年
1期
87-89
,共3页
脑静脉窦血栓形成%全身抗凝治疗%局部溶栓治疗
腦靜脈竇血栓形成%全身抗凝治療%跼部溶栓治療
뇌정맥두혈전형성%전신항응치료%국부용전치료
Cerebral venous sinus%Body anticoagulation%Local thrombolysis
目的 探讨全身抗凝治疗与局部溶栓治疗对脑静脉窦血栓形成的疗效差异. 方法 选择井冈山大学附属医院神经内科自2008年1月至2011年10月收治的脑静脉窦血栓形成患者共42例,根据治疗方式不同分为2组:全身抗凝治疗组及局部溶栓治疗组,每组各21例.对比2组患者NIHSS评分、mRS评分、溶栓后造影及不良反应情况. 结果 全身抗凝治疗组患者神经功能缺损改善率为33.4％,明显低于局部溶栓治疗组的61.9％,差异有统计学意义(P＜0.05).局部溶栓治疗组患者mRS评分明显低于全身抗凝治疗组,差异有统计学意义(P＜0.05).2组患者均行溶栓后造影复查,局部溶栓治疗组患者完全再通率明显高于全身抗凝治疗组,差异有统计学意义(P＜0.05). 结论 局部溶栓治疗较全身抗凝治疗更有利于脑静脉窦血栓形成患者神经系统功能缺损的改善,有助于神经功能的恢复.
目的 探討全身抗凝治療與跼部溶栓治療對腦靜脈竇血栓形成的療效差異. 方法 選擇井岡山大學附屬醫院神經內科自2008年1月至2011年10月收治的腦靜脈竇血栓形成患者共42例,根據治療方式不同分為2組:全身抗凝治療組及跼部溶栓治療組,每組各21例.對比2組患者NIHSS評分、mRS評分、溶栓後造影及不良反應情況. 結果 全身抗凝治療組患者神經功能缺損改善率為33.4％,明顯低于跼部溶栓治療組的61.9％,差異有統計學意義(P＜0.05).跼部溶栓治療組患者mRS評分明顯低于全身抗凝治療組,差異有統計學意義(P＜0.05).2組患者均行溶栓後造影複查,跼部溶栓治療組患者完全再通率明顯高于全身抗凝治療組,差異有統計學意義(P＜0.05). 結論 跼部溶栓治療較全身抗凝治療更有利于腦靜脈竇血栓形成患者神經繫統功能缺損的改善,有助于神經功能的恢複.
목적 탐토전신항응치료여국부용전치료대뇌정맥두혈전형성적료효차이. 방법 선택정강산대학부속의원신경내과자2008년1월지2011년10월수치적뇌정맥두혈전형성환자공42례,근거치료방식불동분위2조:전신항응치료조급국부용전치료조,매조각21례.대비2조환자NIHSS평분、mRS평분、용전후조영급불량반응정황. 결과 전신항응치료조환자신경공능결손개선솔위33.4％,명현저우국부용전치료조적61.9％,차이유통계학의의(P＜0.05).국부용전치료조환자mRS평분명현저우전신항응치료조,차이유통계학의의(P＜0.05).2조환자균행용전후조영복사,국부용전치료조환자완전재통솔명현고우전신항응치료조,차이유통계학의의(P＜0.05). 결론 국부용전치료교전신항응치료경유리우뇌정맥두혈전형성환자신경계통공능결손적개선,유조우신경공능적회복.
Objective To investigate the healing effect of body anticoagulation and local thrombolysis therapy on patients with cerebral venous sinus thrombosis (CVST).Methods Forty two patients with CVST,admitted to our hospital from January 2008 to September 2011,were selected; these patients were divided into body anticoagulation group (n=21) and local thrombolysis group (n=21) according the treatment methods.The National Institutes of Health Stroke Scale (NIHSS) scores,modified Rankin Scale (mRS) scores,angiography imaging and adverse reactions after the treatments were compared between the two groups.Results The nervous system function defect improvement in the body anticoagulation group (33.4％) was significantly lower than that in the local thrombolysis group (61.9％,P＜0.05).The mRS scores in the local thrombolysis group was significantly lower than those in the body anticoagulation group (P＜0.05).Angiography after treatment showed that the completely recanalization rate in the local thrombolysis group was significantly higher than that in the body anticoagulation group (P＜0.05).Conclusion Local thrombolysis,enjoying better effect on nervous system function defect improvement than body anticoagulation,can help the nerve function recovery.
