中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2009年
5期
371-374
,共4页
田曼%赵德育%文惯宇%施圣云
田曼%趙德育%文慣宇%施聖雲
전만%조덕육%문관우%시골운
呼吸道合胞病毒%细支气管炎%喘息%危险因素
呼吸道閤胞病毒%細支氣管炎%喘息%危險因素
호흡도합포병독%세지기관염%천식%위험인소
Respiratory syncytial siruses%Bronchiolitis%Asthma%Risk factors
目的 探讨与呼吸道合胞病毒(RSV)致毛细支气管炎(简称细支炎)及其后反复喘息发作相关的影响因素.方法 对RSV细支炎住院患儿与正常对照组儿童生活生长各因素进行比较,并随访RSV细支炎患儿两年内喘息再发的情况,以期找到与RSV细支炎及其后婴幼儿反复喘息相关的危险因素.结果 ①RSV细支炎组与正常对照组通过Logistic回归分析,筛选出非母乳喂养、被动吸烟、未补充维生素(Vii)AD为具有统计学意义的危险因素.②200例RSV细支炎患儿随访两年,失访82例,细支炎后再发喘息组71例,未再发生喘息组47例.两组通过Logistic回归分析,筛选出被动吸烟、未补充Vit AD、个人特应史、家族特应史为具有统计学意义的危险因素.两组外周血嗜酸细胞计数、RANTES因子、血总IgE水平及TH1/TH2值差异有统计学意义.结论 ①非母乳喂养、被动吸烟、未补充Vit AD为RSV细支炎的危险因素.②被动吸烟、未补充Vit AD、个人特应史、家族特应史为RSV细支炎后反复喘息的危险因素.
目的 探討與呼吸道閤胞病毒(RSV)緻毛細支氣管炎(簡稱細支炎)及其後反複喘息髮作相關的影響因素.方法 對RSV細支炎住院患兒與正常對照組兒童生活生長各因素進行比較,併隨訪RSV細支炎患兒兩年內喘息再髮的情況,以期找到與RSV細支炎及其後嬰幼兒反複喘息相關的危險因素.結果 ①RSV細支炎組與正常對照組通過Logistic迴歸分析,篩選齣非母乳餵養、被動吸煙、未補充維生素(Vii)AD為具有統計學意義的危險因素.②200例RSV細支炎患兒隨訪兩年,失訪82例,細支炎後再髮喘息組71例,未再髮生喘息組47例.兩組通過Logistic迴歸分析,篩選齣被動吸煙、未補充Vit AD、箇人特應史、傢族特應史為具有統計學意義的危險因素.兩組外週血嗜痠細胞計數、RANTES因子、血總IgE水平及TH1/TH2值差異有統計學意義.結論 ①非母乳餵養、被動吸煙、未補充Vit AD為RSV細支炎的危險因素.②被動吸煙、未補充Vit AD、箇人特應史、傢族特應史為RSV細支炎後反複喘息的危險因素.
목적 탐토여호흡도합포병독(RSV)치모세지기관염(간칭세지염)급기후반복천식발작상관적영향인소.방법 대RSV세지염주원환인여정상대조조인동생활생장각인소진행비교,병수방RSV세지염환인량년내천식재발적정황,이기조도여RSV세지염급기후영유인반복천식상관적위험인소.결과 ①RSV세지염조여정상대조조통과Logistic회귀분석,사선출비모유위양、피동흡연、미보충유생소(Vii)AD위구유통계학의의적위험인소.②200례RSV세지염환인수방량년,실방82례,세지염후재발천식조71례,미재발생천식조47례.량조통과Logistic회귀분석,사선출피동흡연、미보충Vit AD、개인특응사、가족특응사위구유통계학의의적위험인소.량조외주혈기산세포계수、RANTES인자、혈총IgE수평급TH1/TH2치차이유통계학의의.결론 ①비모유위양、피동흡연、미보충Vit AD위RSV세지염적위험인소.②피동흡연、미보충Vit AD、개인특응사、가족특응사위RSV세지염후반복천식적위험인소.
Objective To ohserve the correlation factor about early-life RSV bronchiolitis and sequential recurrent wheezing for two years.Methods Follow up the RSV bronehiolitis patients for two years in order to analyze the occurrence of wheezing post-bronchiolitis.Single and multiple logistic regression analysis were used to determined the risk factors such as individual atopy history and familial atopy history,pet feeding,breast milk,secondhand smoke for RSV bronchiolitis and subsequent wheezing.Results①Not breast feeding,exposure to cigarette smoke and the deficiency of VitA.D were the significant risk factors contributed to the RSV bronchiolitis.②Exposure to cigarette smoke,the deficiency of VitA,D,the personal history of atopy and the family history of atopy were the significant risk factors contributed to the post-bronchiolitis wheezing in children.③Those patients who eosinophilia,high serum IgE,RANTES and decreased TH1 to TH2 Ratio were more likely to have wheezing after RSV bronchiolitis.Conclusion①Not breast feeding,exposure to cigarette smoke and the deficiency of VitA,D were the significant risk factors contributed to the RSV bronchiolitis.②Exposure to cigarette smoke,the deficiency of VitA,D,the personal history of atopy and the family history of atopy were the significant risk factors contributed to the pest-bronchiolitis wheezing in children.
