CAJ | 학술논문

湖南省甲型H1N1流感病毒感染状况及快速血清学调查研究
호남성갑형H1N1류감병독감염상황급쾌속혈청학조사연구
Serological survey of pandemic influenza A (H1N1) virus infection among population in Hunan Province

万方数据

中华实验和临床病毒学杂志中華實驗和臨床病毒學雜誌 중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2011年 1期 17-19 ,共3页

刘运芝%王五红%李芳彩%杨浩%张红%邓志红%王媛%陈长%李文超%张恒娇%刘富强%张斯钰%胡世雄

류운지%왕오홍%리방채%양호%장홍%산지홍%왕원%진장%리문초%장항교%류부강%장사옥%호세웅

流感病毒A型,人%感染%免疫学监视流感病毒A型,人%感染%免疫學鑑視
류감병독A형,인%감염%면역학감시
Influenza A virus,human%Infection%Immunologic surveillance

目的了解不同时期湖南省人群甲型H1 N1流感病毒感染状况和评估方法.方法在长沙市选择14个医疗卫生机构于2009年11月至2010年3月期间,先后5次进行甲型H1 N1流感病毒血凝抑制(HI)抗体阳性率快速调查,并与全省抽样调查结果比较.结果共有2131名对象参与快速调查,五次调查的全人群标准化抗体阳性率依次为9.32%、14.62%、31.08%、28.43%和22.80%;6～17岁年龄组人群的抗体阳性率最高;调查对象甲流抗体阳性中仅9.84%可归因于疫苗接种;快速血清学调查与同期全省抽样调查所得标准化抗体阳性率差异无统计学意义(P＞0.05).结论湖南省人群的甲型流感抗体阳性率在2010年1月下旬时最高;在急性传染病大规模流行期间,可以采用小范围的快速调查评估感染状况.
목적 료해불동시기호남성인군갑형H1 N1류감병독감염상황화평고방법.방법 재장사시선택14개의료위생궤구우2009년11월지2010년3월기간,선후5차진행갑형H1 N1류감병독혈응억제(HI)항체양성솔쾌속조사,병여전성추양조사결과 비교.결과 공유2131명대상삼여쾌속조사,오차조사적전인군표준화항체양성솔의차위9.32%、14.62%、31.08%、28.43%화22.80%;6～17세년령조인군적항체양성솔최고;조사대상갑류항체양성중부9.84%가귀인우역묘접충;쾌속혈청학조사여동기전성추양조사소득표준화항체양성솔차이무통계학의의(P＞0.05).결론 호남성인군적갑형류감항체양성솔재2010년1월하순시최고;재급성전염병대규모류행기간,가이채용소범위적쾌속조사평고감염상황.
Objective To understand the infection condition and analytical methods of Influenza A (H1N1 ) virus in the population of Hunan Province during different periods. Methods Quick surveys on the positive rate of Influenza A (H1N1) virus hemagglutination inhibition (HI) test have been conducted for 5 times successively from November 2009 to March 2010 in 14 medical and health institutions of Changsha city, whose results were then compared with those from the sampling surveys of whole Hunan province.Results 2131 subjects were involved in this study; the total population standardized rates of antibody positive investigated for 5 times were 9. 32% , 14. 62%, 31.08%, 28.43% and 22. 80% respectively; the population of 6-17-years-old has the highest rate of antibody positive; only 9. 84% of the antibody positive subjects attributed to vaccine inoculation; there was no significant difference in the standardized positive rates between the quick serological surveys and the corresponding sampling survey of Hunan province( P ＞0.05 ). Conclusion The positive rate of A ( H1N1 ) virus antibody reached the peak in late January 2010;quick investigations in small region could be used to evaluate the infection prevalence during pandemic of infectious diseases.