中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2011年
1期
63-65
,共3页
边立华%王晓莉%郭一帆%吴晓舟%宋磊%刘宏图
邊立華%王曉莉%郭一帆%吳曉舟%宋磊%劉宏圖
변립화%왕효리%곽일범%오효주%송뢰%류굉도
宫颈肿瘤%癌,小细胞%癌,神经内分泌%乳头状瘤病毒,人%聚合酶链反应
宮頸腫瘤%癌,小細胞%癌,神經內分泌%乳頭狀瘤病毒,人%聚閤酶鏈反應
궁경종류%암,소세포%암,신경내분비%유두상류병독,인%취합매련반응
Cervix neoplasms%Carcinoma,small cell%Carcinoma,neuroendocrine%Papillomavirus,human%Polymerase chain reaction
目的 探讨宫颈小细胞神经内分泌癌中高危型人乳头瘤病毒(human papillomavirus,HPV)感染情况.方法 提取1例33岁宫颈小细胞神经内分泌癌患者手术切除组织癌变区域蜡块中的DNA,通过巢式PCR方法 检测其中HPV感染情况.结果 该患者肿瘤切除组织高危型HPV18型阳性.结论 利用巢式PCR方法 分型检测宫颈小细胞神经内分泌癌中的高危型HPV型别,其准确性及敏感性均较高.
目的 探討宮頸小細胞神經內分泌癌中高危型人乳頭瘤病毒(human papillomavirus,HPV)感染情況.方法 提取1例33歲宮頸小細胞神經內分泌癌患者手術切除組織癌變區域蠟塊中的DNA,通過巢式PCR方法 檢測其中HPV感染情況.結果 該患者腫瘤切除組織高危型HPV18型暘性.結論 利用巢式PCR方法 分型檢測宮頸小細胞神經內分泌癌中的高危型HPV型彆,其準確性及敏感性均較高.
목적 탐토궁경소세포신경내분비암중고위형인유두류병독(human papillomavirus,HPV)감염정황.방법 제취1례33세궁경소세포신경내분비암환자수술절제조직암변구역사괴중적DNA,통과소식PCR방법 검측기중HPV감염정황.결과 해환자종류절제조직고위형HPV18형양성.결론 이용소식PCR방법 분형검측궁경소세포신경내분비암중적고위형HPV형별,기준학성급민감성균교고.
Objective To observe the infection of the high risk human papillomavirus (HPV) in the specimen of the small cell neuroendocrine carcinoma of the uterine cervix (SCNEC). Methods We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimen from a 33-year-old patient diagnosed as small cell neuroendocrine carcinoma of uterine cervix and detected the HPV genotype with the nested PCR. Results We identified HPV18, a high-risk genotype, in the specimen. Conclusion The HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffinembedded specimens of small cell neuroendocrine carcinoma of the uterine cervix with a high accuracy and sensitivity.
