CAJ | 학술논문

目的制备一种新型的人工软骨材料并对其进行表征及性能评价.方法将聚甲基丙烯酸羟乙酯(PHEMA)与0.5％二氧化硅(SiO2)及1％～5％羟基磷灰石(HA)复合制备成复合材料,用红外光谱仪和扫描电镜表征了材料的结构,测试材料的吸水性及牛血清白蛋白在材料表面的吸附性.结果 SiO2与HA纳米级均匀地分散在材料的一侧,材料的吸水率为45％～ 50％,牛血清白蛋白在材料表面的吸附率约为5％,表明材料具有较好的生物相容性.结论成功制备1种生物相容性较好的有机/无机复合人工软骨材料.
목적 제비일충신형적인공연골재료병대기진행표정급성능평개.방법 장취갑기병희산간을지(PHEMA)여0.5％이양화규(SiO2)급1％～5％간기린회석(HA)복합제비성복합재료,용홍외광보의화소묘전경표정료재료적결구,측시재료적흡수성급우혈청백단백재재료표면적흡부성.결과 SiO2여HA납미급균균지분산재재료적일측,재료적흡수솔위45％～ 50％,우혈청백단백재재료표면적흡부솔약위5％,표명재료구유교호적생물상용성.결론 성공제비1충생물상용성교호적유궤/무궤복합인공연골재료.
Objective To prepare a kind of novel artificial cartilage and study its cell biocopatibility.Methods Polyhydroxyethyl methacrylate (PHEMA),0.5％ silica and 1％-5％ hydroxyapatite were mixed to prepare the composites.The composites were characterized by Fourier transform infrared spectroscopy (FTIR),scanning electron microscopy (SEM),swelling ratio (SR) measurement and the absorption of bovine serum albumin (BSA).Results Inorganic particles were n nanoscopic diameter and uniformly dispersed on side of the matrices.The swelling ratio of hydrogels was 45％-50％.The absorption of BSA on the surface of composite membrane was about 5％,indicating the good biocompatibility.Conclusion A biocompatible organic/inorganic complex artificial cartilage was prepared.