国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
17期
2657-2660
,共4页
鼻咽癌%迟发性放射性脑病%常规放疗%适型调强放疗
鼻嚥癌%遲髮性放射性腦病%常規放療%適型調彊放療
비인암%지발성방사성뇌병%상규방료%괄형조강방료
Nasopharyngeal carcinoma%Radiation encephalopathy%Two-dimensional radiotherapy%Intensity-modulated radiotherapy
目的 分析鼻咽癌放疗后迟发性放射性脑病的发生、临床特点.方法 收集2006年1月至2008年12月在中山大学肿瘤医院接受鼻咽癌根治放疗后出现迟发性放射性脑病108例患者进行回顾性分析.结果 放射性脑病发生在鼻咽癌放疗后7～74个月,中位40个月,放射性脑病病灶主要分布在颞叶、脑干、额叶,以双侧颞叶多见.局部晚期鼻咽癌患者中多见.结论 放射性脑病多数发生在放疗结束后2～4年内,2D-RT技术具有明显经济优势,调强放疗技术仍存在部分远期并发症,影响患者的生存质量.
目的 分析鼻嚥癌放療後遲髮性放射性腦病的髮生、臨床特點.方法 收集2006年1月至2008年12月在中山大學腫瘤醫院接受鼻嚥癌根治放療後齣現遲髮性放射性腦病108例患者進行迴顧性分析.結果 放射性腦病髮生在鼻嚥癌放療後7～74箇月,中位40箇月,放射性腦病病竈主要分佈在顳葉、腦榦、額葉,以雙側顳葉多見.跼部晚期鼻嚥癌患者中多見.結論 放射性腦病多數髮生在放療結束後2～4年內,2D-RT技術具有明顯經濟優勢,調彊放療技術仍存在部分遠期併髮癥,影響患者的生存質量.
목적 분석비인암방료후지발성방사성뇌병적발생、림상특점.방법 수집2006년1월지2008년12월재중산대학종류의원접수비인암근치방료후출현지발성방사성뇌병108례환자진행회고성분석.결과 방사성뇌병발생재비인암방료후7～74개월,중위40개월,방사성뇌병병조주요분포재섭협、뇌간、액협,이쌍측섭협다견.국부만기비인암환자중다견.결론 방사성뇌병다수발생재방료결속후2～4년내,2D-RT기술구유명현경제우세,조강방료기술잉존재부분원기병발증,영향환자적생존질량.
Objective To study the clinical characteristics of radiation encephalopathy (REP) after radiotherapy in patients with nasopharyngeal carcinoma (NPC).Methods Retrospective analysis was carried out to study the clinical characteristics of 108 patients diagnosed as REP with NPC treated with radiotherapy in Sun Yat-sen University Cancer Center from 2006 to 2008.Results REP occurred ranged from 7 to 74 months (median 40 months) after radiotherapy.REP was mainly distributed in the temporal lobe,brain stem,frontal lobe,bilateral temporal lobe.It mainly occurred in patients with locally advanced nasopharyngeal carcinoma.Conclusion REP occurred within 2-4 years after radiotherapy.2D-RT is a more economic choice for patients who can not afford intensity modulated radiation therapy (IMRT).The IMRT showed survival benefits and good normal tissue protection for nasopharyngeal carcinoma patients.There was still some long-term complication in IMRT,which could affect the quality of life of patients.
