中华肾脏病杂志
中華腎髒病雜誌
중화신장병잡지
2010年
2期
99-104
,共6页
温继兰%王凤仙%李秉程%李荣山%石媛媛%王素萍
溫繼蘭%王鳳仙%李秉程%李榮山%石媛媛%王素萍
온계란%왕봉선%리병정%리영산%석원원%왕소평
肾疾病,慢性%患病率%流行病学%影响因素
腎疾病,慢性%患病率%流行病學%影響因素
신질병,만성%환병솔%류행병학%영향인소
Kidney disease,chronic%Prevalence%Epidemiotogy%Influential factors
目的 研究山西省右玉县城镇成人慢性肾脏病(CKD)的患病率及其影响因素,以便提出相应的防治措施.方法 采用随机整群抽样的方法抽取右玉县城18岁以上的居民3603名进行CKD及其影响因素的问卷调查和相关检测.结果 (1)资料完整的为3502名,经年龄和性别校正后,白蛋白尿患病率为6.8%(95%CI:6.5%～7.1%);血尿患病率为7.1%(95%CI:6.8%～7.4%);估算肾小球滤过率(eGFR)下降患病率为2.0%(95%CI:1.8%～2.2%).该人群CKD患病率为15.1%(95%CI:14.5%～15.5%),知晓率为6.9%.(2)女性白蛋白尿、血尿和eGFR下降的患病率均显著高于男性(均P＜0.01).(3)白蛋白尿、eGFR下降和CKD患病率均随年龄增加而逐渐增加,男女均有同样趋势(均P＜0.01),而总体血尿与年龄无关.(4)多因素Logistic回归分析显示,白蛋白尿与性别、糖代谢异常、高脂血症、肾病史及心血管疾病史独立相关;eGFR下降与性别、年龄、高血压、糖代谢异常、肾病史、肾病家族史及白蛋白尿独立相关;血尿与性别相关.结论 山西省右玉县城镇成人的CKD患病率较高,危险因素与国内发达城市和西方国家类似.在经济不太发达地区开展CKD防治工作更为迫切.
目的 研究山西省右玉縣城鎮成人慢性腎髒病(CKD)的患病率及其影響因素,以便提齣相應的防治措施.方法 採用隨機整群抽樣的方法抽取右玉縣城18歲以上的居民3603名進行CKD及其影響因素的問捲調查和相關檢測.結果 (1)資料完整的為3502名,經年齡和性彆校正後,白蛋白尿患病率為6.8%(95%CI:6.5%～7.1%);血尿患病率為7.1%(95%CI:6.8%～7.4%);估算腎小毬濾過率(eGFR)下降患病率為2.0%(95%CI:1.8%～2.2%).該人群CKD患病率為15.1%(95%CI:14.5%～15.5%),知曉率為6.9%.(2)女性白蛋白尿、血尿和eGFR下降的患病率均顯著高于男性(均P＜0.01).(3)白蛋白尿、eGFR下降和CKD患病率均隨年齡增加而逐漸增加,男女均有同樣趨勢(均P＜0.01),而總體血尿與年齡無關.(4)多因素Logistic迴歸分析顯示,白蛋白尿與性彆、糖代謝異常、高脂血癥、腎病史及心血管疾病史獨立相關;eGFR下降與性彆、年齡、高血壓、糖代謝異常、腎病史、腎病傢族史及白蛋白尿獨立相關;血尿與性彆相關.結論 山西省右玉縣城鎮成人的CKD患病率較高,危險因素與國內髮達城市和西方國傢類似.在經濟不太髮達地區開展CKD防治工作更為迫切.
목적 연구산서성우옥현성진성인만성신장병(CKD)적환병솔급기영향인소,이편제출상응적방치조시.방법 채용수궤정군추양적방법추취우옥현성18세이상적거민3603명진행CKD급기영향인소적문권조사화상관검측.결과 (1)자료완정적위3502명,경년령화성별교정후,백단백뇨환병솔위6.8%(95%CI:6.5%～7.1%);혈뇨환병솔위7.1%(95%CI:6.8%～7.4%);고산신소구려과솔(eGFR)하강환병솔위2.0%(95%CI:1.8%～2.2%).해인군CKD환병솔위15.1%(95%CI:14.5%～15.5%),지효솔위6.9%.(2)녀성백단백뇨、혈뇨화eGFR하강적환병솔균현저고우남성(균P＜0.01).(3)백단백뇨、eGFR하강화CKD환병솔균수년령증가이축점증가,남녀균유동양추세(균P＜0.01),이총체혈뇨여년령무관.(4)다인소Logistic회귀분석현시,백단백뇨여성별、당대사이상、고지혈증、신병사급심혈관질병사독립상관;eGFR하강여성별、년령、고혈압、당대사이상、신병사、신병가족사급백단백뇨독립상관;혈뇨여성별상관.결론 산서성우옥현성진성인적CKD환병솔교고,위험인소여국내발체성시화서방국가유사.재경제불태발체지구개전CKD방치공작경위박절.
Objective To investigate the prevalence of urban adult chronic kidney disease(CKD)and influential factors in Youyu county of Shanxi province in order to provide evidences for the treatment and prevention of CKD.Methods A total of 3603 residents aged ≥ 18 years old in Youyu county were selected by random cluster sampling.They were interviewed with questionnaire and tested for ulbuminuria,haematuria and renal function.Associations among demographic characteristics,health characteristies(eg.overweight or obesity,hypertension,giycometabolism abnormity)and indicators of kidney damage were examined.Results (1)Eligible data of 3502 subjects were enrolled in the study.After adjustment for age and gender,the prevalence of albuminuria,haematuria and reduced estimated glomemlar filtration rate(eGFR)was 6.8%(95%CI:6.5%-7.1%),7.1%(95%CI:6.8%-7.4%)and 2.0%(95%CI:1.8%-2.2%),respectively.Approximately 15.1%(95%C1:14.5%-15.5%)subjects had at least one indicator of kidney damage.The awareness rate of CKD was 6.9%.(2)Female had higher prevalence of albuminuria,hematuria and reduced eGFR than male(P＜0.01).(3)Albuminuria,reduced eGFR and CKD prevalence increased with age no matter male or female(P＜0.01),butoverall prevalence of hematuria was not associated with age.(4)Albuminuria was independently associated with gender,glycometabolism abnormity,hyperlipidemia,kidney disease history and the history of cardiovascular disease.Reduced eGFR was independently associated with gender,age,hypertension,glycometabolism abnormity,kidney disease history,family history of kidney disease,and microalbuminuria.Haematuria was independently associated with female.Conclusions The prevalence of adult CKD is quite high in Youyu county of Shanxi province,and the risk factors are similar to that of domestic well-developed cities and western countries.It shows a more urgent need for CKD prevention and control work in the economic underdeveloped areas.
