CAJ | 학술논문

目的探讨持续性非卧床腹膜透析(CAPD)患者继发性甲状旁腺功能亢进(SHPT)的患病率及相关因素.方法分析2011年7月至2012年1月在本院腹膜透析中心规律随访的CAPD患者数据库资料.所有患者根据全段甲状旁腺激素(iPTH)分为甲状旁腺功能亢进组及甲状旁腺功能非亢进组.通过Logistic回归分析SHPT的相关影响因素.结果共纳入639例患者,SHPT的患病率为46.95％.Logistic多因素回归分析结果显示,低血红蛋白、低血钙、高血磷、高碱性磷酸酶、高血肌酐、高标准化蛋白分解代谢率(nPCR)及低钙透析液是SHPT的独立影响因素.结论 CAPD患者中SHPT患病率较高,钙磷代谢异常、高蛋白饮食、肾性贫血及低钙透析液是影响SHPT发生的独立因素.
목적 탐토지속성비와상복막투석(CAPD)환자계발성갑상방선공능항진(SHPT)적환병솔급상관인소.방법 분석2011년7월지2012년1월재본원복막투석중심규률수방적CAPD환자수거고자료.소유환자근거전단갑상방선격소(iPTH)분위갑상방선공능항진조급갑상방선공능비항진조.통과Logistic회귀분석SHPT적상관영향인소.결과 공납입639례환자,SHPT적환병솔위46.95％.Logistic다인소회귀분석결과현시,저혈홍단백、저혈개、고혈린、고감성린산매、고혈기항、고표준화단백분해대사솔(nPCR)급저개투석액시SHPT적독립영향인소.결론 CAPD환자중SHPT환병솔교고,개린대사이상、고단백음식、신성빈혈급저개투석액시영향SHPT발생적독립인소.
Objective To study the prevalence and associated factors of secondary hyperparathyroidism (SHPT) in continuous ambulatory peritoneal dialysis (CAPD) patients.Methods A cross-section study was performed.A total of 639 eligible participants undergoing CAPD treatment more than three months in our peritoneal dialysis center from July 2011 to January 2012 were recruited in the study.All the patients were divided into SHPT group and non-SHPT group according to the intact parathyroid hormone (iPTH) level,and the associated factors of SHPT were investigated through Logistic regression analysis.Results The prevalence of SHPT was 46.95％ (300/639).Logistic regression analysis demonstrated that lower hemoglobin,hypocalcemia,hyperphosphatemia,higher alkaline phosphatase,higher Scr,higher nPCR and low calcium dialysate were independent influencing factors of SHPT.Conclusions The prevalence of SHPT is quite high in CAPD patients.Abnormal calcium-phosphorus metabolism,renal anemia,high protein diet and low calium dialysate may affect the SHPT.