CAJ | 학술논문

目的了解广西壮族村落成人慢性肾脏病(CKD)的患病率、知晓率及流行病学特点,探讨相关危险因素.方法通过整群抽样,选择广西南宁良庆区新兰村(壮族聚居村)做为整群调查点；选取全村18岁以上常住村民进行问卷调查,并检测肾脏损伤指标及研究相关危险因素.结果在资料完整的2036例村民中,壮族农业人口占99.8％.肾功能下降患病率为2.2％；白蛋白尿患病率为1.1％；血尿患病率为3.4％；高血压患病率为11.6％；糖尿病患病率为1.8％.经过年龄及性别标化后,CKD患病率为5.7％,知晓率为5.3％.二分类Logistic回归分析提示,性别、年龄、高血压与CKD独立相关.结论在经济文化相对落后的广西南宁某壮族村落成人CKD患病率为5.7％,知晓率仅5.3％.CKD独立危险因素为性别、年龄、高血压,与其他研究相似.
목적 료해엄서장족촌락성인만성신장병(CKD)적환병솔、지효솔급류행병학특점,탐토상관위험인소.방법 통과정군추양,선택엄서남저량경구신란촌(장족취거촌)주위정군조사점；선취전촌18세이상상주촌민진행문권조사,병검측신장손상지표급연구상관위험인소.결과 재자료완정적2036례촌민중,장족농업인구점99.8％.신공능하강환병솔위2.2％；백단백뇨환병솔위1.1％；혈뇨환병솔위3.4％；고혈압환병솔위11.6％；당뇨병환병솔위1.8％.경과년령급성별표화후,CKD환병솔위5.7％,지효솔위5.3％.이분류Logistic회귀분석제시,성별、년령、고혈압여CKD독립상관.결론 재경제문화상대락후적엄서남저모장족촌락성인CKD환병솔위5.7％,지효솔부5.3％.CKD독립위험인소위성별、년령、고혈압,여기타연구상사.
Objective To investigate the prevalence and risk factors of chronic kidney disease (CKD) in the rural adult population of Zhuang nationality from the Guangxi Zhuang Autonomous Region.Methods A cross-sectional survey in a village of Zhuang agglomerated settlement was performed by cluster sampling.Demography data of participants were collected using questionnaire.Kidney damage indexes were examined and risk factors were explored.Morning spot urine albumin to creatinine ratio ≥ 30 mg/g was defined as albuminuria.Estimated glomerular filtration rate (eGFR) by abbreviated MDRD equation ＜ 60 ml· min-1· (1.73 m2)-1 was defined as reduced renal function.Morning spot urine dipstick (1 + or greater) and then ＞ 3 red blood cells/HP by microscopy was defined as hematuria.The crude and adjusted prevalence of indicators of kidney damage were calculated and risk factors associated with the presence of CKD was analyzed by Logistic regression.Results A total of 2104 subjects older than 18 years were enrolled in the study,of whom 2036 persons agreed and completed.After adjustment for age and gender,the prevalence of albuminuria,haematuria and reduced eGFR was 1.1％,3.4％ and 2.2％,respectively.The prevalence of chronic kidney disease was 5.7 ％ and the awareness rate was 5.3 ％.Independent risk factors associated with CKD were age,gender and hypertension.Conclusions In the Zhuang nationality village of Guangxi Zhuang Autonomous Region,5.7 ％ people have either proteinuria,haematuria and/or reduced eGFR,indicating the presence of kidney damage,with awareness rate of only 5.3％.Independent risk factors associated with chronic kidney disease are age,gender and hypertension,which are similar to developed countries and domestic big cities.