中华物理医学与康复杂志
中華物理醫學與康複雜誌
중화물리의학여강복잡지
CHINESE JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
2014年
2期
111-114
,共4页
A型肉毒毒素%痉挛性斜颈%康复训练%生活质量
A型肉毒毒素%痙攣性斜頸%康複訓練%生活質量
A형육독독소%경련성사경%강복훈련%생활질량
Botulinum toxin type A%Spasmodic torticollis%Rehabilitation%Quality of life
目的 观察局部注射A型肉毒毒素联合康复干预对痉挛性斜颈患者痉挛病情及生活质量的影响.方法 采用随机数字表法将38例痉挛性斜颈患者分为联合治疗组及对照组.2组患者均给予局部肌肉A型肉毒毒素注射,联合治疗组于A型肉毒毒素注射1周后给予康复干预.于治疗前、A型肉毒毒素注射1周后及注射8周后分别采用多伦多痉挛性斜颈评定量表(TWSTRS)、Tsui量表对患者疗效进行评定,采用健康调查量表(SF-36)对患者生活质量改善情况进行评估.结果 经A型肉毒毒素注射8周后,发现联合治疗组TWSTRS量表病情严重程度评分[(9.5±2.6)分]、残疾程度评分[(5.9±4.1)分]、躯体疼痛评分[(3.7±1.5)分]、SF-36量表生理职能评分[(68.3±19.5)分]、生理机能评分[(80.6±19.1)分]、活力评分[(76.3±20.3)分]、精神健康评分[(74.3±22.5)分]及Tsui量表评分[(3.2±1.6)分]均较治疗前明显改善(P＜0.05),其中生理职能、躯体疼痛、活力、精神健康及Tsui评分与对照组间差异均具有统计学意义(P＜0.05).对照组仅发现病情严重程度评分[(1 1.4±3.6)分]、Tsui量表评分[(5.8±1.7)分]与治疗前差异具有统计学意义(P＜0.05).结论 在常规应用肉毒毒素基础上辅以康复训练治疗痉挛性斜颈具有协同疗效,能进一步缓解疼痛、降低伤残评分、提高患者生活质量.
目的 觀察跼部註射A型肉毒毒素聯閤康複榦預對痙攣性斜頸患者痙攣病情及生活質量的影響.方法 採用隨機數字錶法將38例痙攣性斜頸患者分為聯閤治療組及對照組.2組患者均給予跼部肌肉A型肉毒毒素註射,聯閤治療組于A型肉毒毒素註射1週後給予康複榦預.于治療前、A型肉毒毒素註射1週後及註射8週後分彆採用多倫多痙攣性斜頸評定量錶(TWSTRS)、Tsui量錶對患者療效進行評定,採用健康調查量錶(SF-36)對患者生活質量改善情況進行評估.結果 經A型肉毒毒素註射8週後,髮現聯閤治療組TWSTRS量錶病情嚴重程度評分[(9.5±2.6)分]、殘疾程度評分[(5.9±4.1)分]、軀體疼痛評分[(3.7±1.5)分]、SF-36量錶生理職能評分[(68.3±19.5)分]、生理機能評分[(80.6±19.1)分]、活力評分[(76.3±20.3)分]、精神健康評分[(74.3±22.5)分]及Tsui量錶評分[(3.2±1.6)分]均較治療前明顯改善(P＜0.05),其中生理職能、軀體疼痛、活力、精神健康及Tsui評分與對照組間差異均具有統計學意義(P＜0.05).對照組僅髮現病情嚴重程度評分[(1 1.4±3.6)分]、Tsui量錶評分[(5.8±1.7)分]與治療前差異具有統計學意義(P＜0.05).結論 在常規應用肉毒毒素基礎上輔以康複訓練治療痙攣性斜頸具有協同療效,能進一步緩解疼痛、降低傷殘評分、提高患者生活質量.
목적 관찰국부주사A형육독독소연합강복간예대경련성사경환자경련병정급생활질량적영향.방법 채용수궤수자표법장38례경련성사경환자분위연합치료조급대조조.2조환자균급여국부기육A형육독독소주사,연합치료조우A형육독독소주사1주후급여강복간예.우치료전、A형육독독소주사1주후급주사8주후분별채용다륜다경련성사경평정량표(TWSTRS)、Tsui량표대환자료효진행평정,채용건강조사량표(SF-36)대환자생활질량개선정황진행평고.결과 경A형육독독소주사8주후,발현연합치료조TWSTRS량표병정엄중정도평분[(9.5±2.6)분]、잔질정도평분[(5.9±4.1)분]、구체동통평분[(3.7±1.5)분]、SF-36량표생리직능평분[(68.3±19.5)분]、생리궤능평분[(80.6±19.1)분]、활력평분[(76.3±20.3)분]、정신건강평분[(74.3±22.5)분]급Tsui량표평분[(3.2±1.6)분]균교치료전명현개선(P＜0.05),기중생리직능、구체동통、활력、정신건강급Tsui평분여대조조간차이균구유통계학의의(P＜0.05).대조조부발현병정엄중정도평분[(1 1.4±3.6)분]、Tsui량표평분[(5.8±1.7)분]여치료전차이구유통계학의의(P＜0.05).결론 재상규응용육독독소기출상보이강복훈련치료경련성사경구유협동료효,능진일보완해동통、강저상잔평분、제고환자생활질량.
Objective To observe the impact of an injection of botulinum toxin type A combined with rehabilitation on the quality of life (QOL) of patients with spasmodic torticollis.Methods Thirty-eight patients with spasmodic torticollis were randomly divided into a combined treatment group and control group.Both groups were given a local muscular injection of botulinum toxin type A.One week later the combined group was given rehabilitation training.Both groups were assessed using the Toronto torticollis rating scale (TWSTRS),Tsui's scale and a health survey (SF-36) one week and eight weeks after the injection.Results Eight weeks after the injection,severity,disability,pain,physical functioning,vitality,mental health and Tsui scores had all increased significantly in the combined treatment group compared with before treatment.Physical functioning,pain,vitality,mental health and Tsui scores had also improved significantly compared with the control group.In the control group,only severity and Tsui scores were significantly improved compared with before treatment.Throughout the course of treatment there were no significant adverse reactions.Conclusions Combining botulinum toxin type A with rehabilitation has synergistic effects on spasmodic torticollis.It can significantly reduce disability scores,relieve pain and improve quality of life.
