CAJ | 학술논문

目的研究重度颅脑创伤(TBI)后认知障碍患者蒙特利尔认知评估量表(MoCA)评分与扩散张量成像(DTI)的相关性.方法选择重度TBI恢复期男性患者8例作为研究对象,所有患者均采用MoCA评分评定其记忆、注意、语言、执行等各项功能,同时采用DTI测量感兴趣区(放射冠、上纵束、下纵束、内囊、胼胝体膝部、胼胝体体部、胼胝体压部和扣带回)白质纤维束的各异向性(FA)值,最后采用Pearson软件分析MoCA评分与感兴趣区FA值的相关性.结果胼胝体体部、胼胝体膝部和上纵束的FA值与MoCA评分均具有相关性,r值分别为r =0.746,P ＜0.05;r=0.689,P＜ 0.05;r =0.748,P＜0.05.结论重度颅脑创伤患者的胼胝体体部、胼胝体膝部、上纵束白质纤维束损伤与认知障碍显著的相关性.
목적 연구중도로뇌창상(TBI)후인지장애환자몽특리이인지평고량표(MoCA)평분여확산장량성상(DTI)적상관성.방법 선택중도TBI회복기남성환자8례작위연구대상,소유환자균채용MoCA평분평정기기억、주의、어언、집행등각항공능,동시채용DTI측량감흥취구(방사관、상종속、하종속、내낭、변지체슬부、변지체체부、변지체압부화구대회)백질섬유속적각이향성(FA)치,최후채용Pearson연건분석MoCA평분여감흥취구FA치적상관성.결과 변지체체부、변지체슬부화상종속적FA치여MoCA평분균구유상관성,r치분별위r =0.746,P ＜0.05;r=0.689,P＜ 0.05;r =0.748,P＜0.05.결론 중도로뇌창상환자적변지체체부、변지체슬부、상종속백질섬유속손상여인지장애현저적상관성.
Objective To investigate any correlation between diffusion tensor imaging (DTI) results and Montreal cognitive assessment (MoCA) scores after severe traumatic brain injury (TBI).Methods Eight male pa-tients with chronic severe TBI were given the MoCA (including memory,attention,speech and executive function).DTI was used to quantify the fractional anisotropy (FA) of white matter fiber tracts in the radial and longitudinal fasciculus,under longitudinal fasciculus,internal capsule,corpus callosum genu and body,and the cingulate cortex.Pearson correlation coefficients were calculated to quantify the correlation between the FA values and MoCA scores.Results There was a positive correlation between FA in the corpus callosum body,corpus callosum genu and the superior longitudinal fasciculus and MoCA total scores.Conclusion The MoCA scores of patients with chronic severe TBI are related to white matter damage in the corpus callosum body,corpus callosum genu and the superior longitudinal fasciculus.