中华消化内镜杂志
中華消化內鏡雜誌
중화소화내경잡지
CHINESE JOURNAL OF DIGESTIVE ENDOSCOPY
2013年
1期
10-14
,共5页
叶博%胡良皞%廖专%孙涛%刘牧云%孙畅%邹文斌%辛磊%邹多武
葉博%鬍良皞%廖專%孫濤%劉牧雲%孫暢%鄒文斌%辛磊%鄒多武
협박%호량호%료전%손도%류목운%손창%추문빈%신뢰%추다무
慢性胰腺炎%内镜治疗%体外震波碎石%手术%临床特征%治疗模式
慢性胰腺炎%內鏡治療%體外震波碎石%手術%臨床特徵%治療模式
만성이선염%내경치료%체외진파쇄석%수술%림상특정%치료모식
Chronic pancreatitis%Endotherapy%Extracorporeal shock wave lithotripsy%Surgery%Clinical features%Therapeutic mold
目的 探讨长海医院近20年收治慢性胰腺炎患者的临床特征和治疗模式变迁.方法 回顾性分析长海医院1995年至2012年收治的2180例慢性胰腺炎的病因、临床特征、合并症以及治疗方式等.结果 2180例患者中,男女比例为2.24:1,平均年龄(46.24±15.99)岁.病因学方面,酒精性740例(33.95％),特发性1336例(61.28％),先天性胰腺发育异常88例(4.04％),遗传性16例(0.73％).合并症方面,535例(24.54％)伴有糖尿病,322例(14.77％)伴有脂肪泻,108例(4.95％)伴有胆管狭窄.1440例患者(66.06％)接受了内镜治疗,490例(22.48％)接受了体外震波碎石治疗,468例患者(21.47％)接受了外科手术治疗.内镜和外科手术治疗的比例由2000年之前的0.73∶1上升到2012年的17.6∶1.内镜治疗组和外科手术组并发症发生率分别为4.25％和3.42％ (P ＞0.05).结论 研究揭示了我国慢性胰腺炎的病因、合并症和治疗现状,内镜为主的微创系列治疗已经取代了部分外科手术,成为慢性胰腺炎的一线治疗.
目的 探討長海醫院近20年收治慢性胰腺炎患者的臨床特徵和治療模式變遷.方法 迴顧性分析長海醫院1995年至2012年收治的2180例慢性胰腺炎的病因、臨床特徵、閤併癥以及治療方式等.結果 2180例患者中,男女比例為2.24:1,平均年齡(46.24±15.99)歲.病因學方麵,酒精性740例(33.95％),特髮性1336例(61.28％),先天性胰腺髮育異常88例(4.04％),遺傳性16例(0.73％).閤併癥方麵,535例(24.54％)伴有糖尿病,322例(14.77％)伴有脂肪瀉,108例(4.95％)伴有膽管狹窄.1440例患者(66.06％)接受瞭內鏡治療,490例(22.48％)接受瞭體外震波碎石治療,468例患者(21.47％)接受瞭外科手術治療.內鏡和外科手術治療的比例由2000年之前的0.73∶1上升到2012年的17.6∶1.內鏡治療組和外科手術組併髮癥髮生率分彆為4.25％和3.42％ (P ＞0.05).結論 研究揭示瞭我國慢性胰腺炎的病因、閤併癥和治療現狀,內鏡為主的微創繫列治療已經取代瞭部分外科手術,成為慢性胰腺炎的一線治療.
목적 탐토장해의원근20년수치만성이선염환자적림상특정화치료모식변천.방법 회고성분석장해의원1995년지2012년수치적2180례만성이선염적병인、림상특정、합병증이급치료방식등.결과 2180례환자중,남녀비례위2.24:1,평균년령(46.24±15.99)세.병인학방면,주정성740례(33.95％),특발성1336례(61.28％),선천성이선발육이상88례(4.04％),유전성16례(0.73％).합병증방면,535례(24.54％)반유당뇨병,322례(14.77％)반유지방사,108례(4.95％)반유담관협착.1440례환자(66.06％)접수료내경치료,490례(22.48％)접수료체외진파쇄석치료,468례환자(21.47％)접수료외과수술치료.내경화외과수술치료적비례유2000년지전적0.73∶1상승도2012년적17.6∶1.내경치료조화외과수술조병발증발생솔분별위4.25％화3.42％ (P ＞0.05).결론 연구게시료아국만성이선염적병인、합병증화치료현상,내경위주적미창계렬치료이경취대료부분외과수술,성위만성이선염적일선치료.
Objective To evaluate the clinical features of chronic pancreatitis (CP) patients admitted to Changhai Hospital in recent 20 years and some changes in treatment.Methods Data of 2180 CP patients admitted from 1995 to 2012 were retrospectively analyzed for the etiology,clinical symptoms,therapies and complication rates.Results Males to females ratio was 2.24∶ 1,mean age 46.24 ± 15.99 years old.In terms of etiology,there were 740 cases of alcoholic CP (33.95％),1336 cases of idiopathic CP (61.28％),88 congenital pancreatic abnormalities (4.04％) and 16 hereditary CP (0.73％).In the respect of complications,535 patients (24.54％) were complicated with diabetes,322 (14.77％) with steatorrhea and 108 (4.95％) with biliary strictures.In therapy,1440 patients (66.06％) were treated by endoscopy,490 patients underwent ESWL,and 468 patients (21.47％) accepted surgery.The radio of endoscopic therapy to surgical therapy increased from 0.73 ∶ 1 in 2000 to 17.6 ∶ 1 in 2012.The postoperative complication rates of endotherapy,ESWL and surgery were 4.25％,4.18％ and 3.42％ respectively,which had no statistically significant difference (P ＞ 0.05).Conclusion The mini-invasive endotherapy has partly replaced pancreatic surgery and become the first therapy for CP patients.
