CAJ | 학술논문

目的评价超声内镜引导下细针穿刺(EUS-FNA)联合流式细胞术(FCM)对淋巴瘤的诊断价值.方法回顾性分析2011年1月至12月上海瑞金医院收治的疑似淋巴瘤患者,行EUS-FNA且穿刺标本行FCM检测,以手术或活组织检查病理和随访结果为最终诊断,初步分析EUS-FNA联合FCM对淋巴瘤诊断的灵敏度、特异度、准确度.结果共收集14例疑似淋巴瘤患者,最终经手术病理或活组织检查病理确诊为淋巴瘤8例,非淋巴瘤性病变4例,2例患者未得到最终诊断.单独依靠FCM对淋巴瘤诊断的灵敏度均为4/8,特异度为4/4.EUS-FNA联合FCM检出淋巴瘤6例,对淋巴瘤诊断的灵敏度为6/8,特异度为4/4,准确度为10/12.结论 EUS-FNA联合FCM对淋巴瘤具有较好的诊断价值,尤其对于胃肠道及其周边深部病变更具显著优势.
목적 평개초성내경인도하세침천자(EUS-FNA)연합류식세포술(FCM)대림파류적진단개치.방법 회고성분석2011년1월지12월상해서금의원수치적의사림파류환자,행EUS-FNA차천자표본행FCM검측,이수술혹활조직검사병리화수방결과위최종진단,초보분석EUS-FNA연합FCM대림파류진단적령민도、특이도、준학도.결과 공수집14례의사림파류환자,최종경수술병리혹활조직검사병리학진위림파류8례,비림파류성병변4례,2례환자미득도최종진단.단독의고FCM대림파류진단적령민도균위4/8,특이도위4/4.EUS-FNA연합FCM검출림파류6례,대림파류진단적령민도위6/8,특이도위4/4,준학도위10/12.결론 EUS-FNA연합FCM대림파류구유교호적진단개치,우기대우위장도급기주변심부병변경구현저우세.
Objective To evaluate the diagnostic value of endoscopic ultrasound guided fine needle aspiration (EUS-FNA) in combination with flow cytometry (FCM) in lymphoma.Methods From January 2011 to December 2011,the cases of suspicious lymphoma with EUS-FNA examination at Shanghai Ruijin Hospital were retrospectively analyzed.The final diagnosis was according to pathological diagnosis of specimen from the surgery and follow up results.The sensitivity,specificity and accuracy of EUS-FNA combined with FCM in lymphoma diagnosis were initially analyzed.Results A total of 14 suspicious lymphoma patients were collected,eight cases were diagnosed as lymphoma by pathological examination of specimen from the surgery or.tissue from aspiration,four cases were non-lymphoma lesions and two cases still had no final diagnosis.The sensitivity and specificity of FCM alone in lymphoma diagnosis were 4/8 and 4/4 respectively.Six cases of lymphoma were detected by EUS-FNA with FCM.The sensitivity,specificity and accuracy of EUS FNA combined with FCM were 6/8,6/6 and 10/12 respectively.Conclusion EUS-FNA combined with FCM has better diagnostic value in lymphoma,especially for gastrointestinal lymphoma and those surrounding deep lesions.