CAJ | 학술논문

目的探讨贲门失弛缓症患者高分辨率测压(HRM)结果的变化.方法收集24例贲门失弛缓症患者行HRM检测并分型,对不同亚型患者的食管压力测定数据进行分析.计数资料采用卡方检验,计量资料采用两独立样本t检验.结果 24例贲门失弛缓症患者中,Ⅰ型5例,以男性为主；Ⅱ型18例,女性多于男性；Ⅲ型1例,为男性.Ⅰ型患者体质量减轻的发生率高于Ⅱ型(x2=6.97,P=0.008),Ⅰ型患者胸痛和食物反流的发生率高于Ⅱ型,但差异无统计学意义(P均＞0.05).电极插入胃腔的20例患者中,下食管括约肌(LES)上缘距鼻孔平均距离为(44.9±3.3) cm,LES下缘距鼻孔平均距离为(48.0±3.2) cm,LES平均总长度为(3.1±0.7)cm,腹腔内LES平均长度为(2.1±0.5) cm,LES平均静息压为(34.6±13.8) mm Hg(1 mm Hg=0.133 kPa),完整松弛压(IRP)为(31.1±12.0)mm Hg.结论食管测压是贲门失弛缓症诊断的金标准,HRM可更加简便、直观和准确地检测食管功能.
목적 탐토분문실이완증환자고분변솔측압(HRM)결과적변화.방법 수집24례분문실이완증환자행HRM검측병분형,대불동아형환자적식관압력측정수거진행분석.계수자료채용잡방검험,계량자료채용량독립양본t검험.결과 24례분문실이완증환자중,Ⅰ형5례,이남성위주；Ⅱ형18례,녀성다우남성；Ⅲ형1례,위남성.Ⅰ형환자체질량감경적발생솔고우Ⅱ형(x2=6.97,P=0.008),Ⅰ형환자흉통화식물반류적발생솔고우Ⅱ형,단차이무통계학의의(P균＞0.05).전겁삽입위강적20례환자중,하식관괄약기(LES)상연거비공평균거리위(44.9±3.3) cm,LES하연거비공평균거리위(48.0±3.2) cm,LES평균총장도위(3.1±0.7)cm,복강내LES평균장도위(2.1±0.5) cm,LES평균정식압위(34.6±13.8) mm Hg(1 mm Hg=0.133 kPa),완정송이압(IRP)위(31.1±12.0)mm Hg.결론 식관측압시분문실이완증진단적금표준,HRM가경가간편、직관화준학지검측식관공능.
Objective To investigate the dynamic changes in achalasia patients by using high resolution manometry (HRM).Methods Twenty-four achalasia patients were enrolled for HRM examination and typing.The esophageal pressure of patients with different subtypes was analyzed.Chi-square test was used for count data analysis.Two independent samples t-test was used for measurement data.Results Among twenty-four achalasia patients,five patients were type Ⅰ and maledominated,18 patients were type Ⅱ and female was more than male,and only one male patient was type Ⅲ.The frequency of weight loss in type Ⅰ was higher than that of type Ⅱ (x2 =6.97,P=0.008).The frequency of chest pain and food reflux in type Ⅰ was higher than that of type Ⅱ (both P＞0.05).The average distance from the nares to the upper edge of the lower esophageal sphincter (LES) with the electrode successfully inserted into the stomach was (44.9±3.3) cm and to the lower edge of the LES was (48.0±3.2) cm.The average LES length was (3.1 ±0.7) cm,average intraabdominal LES length was (2.1 ±0.5) cm.The average LES resting pressure was (34.6 ± 13.8) mm Hg (1 mm Hg =0.133 kPa) and the integrated relaxation pressure (IRP) was (31.1 ± 12.0) mm Hg.Conclusion Esophageal manometry is the golden standard for achalasia diagnosis,and HRM may be a simple,direct viewing and accurate method for accessing esophageal motor function.