中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2013年
2期
93-96
,共4页
任玲%顾立扬%李海燕%宋燕%李晓波
任玲%顧立颺%李海燕%宋燕%李曉波
임령%고립양%리해연%송연%리효파
结肠镜检查%手术前护理%聚乙烯二醇类%电解质%苯甲酰胺类%便秘
結腸鏡檢查%手術前護理%聚乙烯二醇類%電解質%苯甲酰胺類%便祕
결장경검사%수술전호리%취을희이순류%전해질%분갑선알류%편비
Colonoscopy%Preoperative care%Polyethylene glycols%Electrolytes%Benzamides%Constipation
目的 观察促胃肠动力药伊托必利在便秘患者结肠镜检查前肠道清洁中的作用.方法 将需要结肠镜检查的有慢性便秘史的门诊连续病例115例纳入研究,根据肠道准备方案分为3组:A组39例,检查前6h服用标准剂量复方聚乙二醇电解质溶液；B组38例,口服A组洗肠液前30 min口服150 mg伊托必利；C组38例,检查前1d上午7点、上午12点、下午8点各口服150 mg伊托必利,检查当天用药同B组.三组患者用药前后监测血压、心率及电解质等.观察各组患者肠道清洁度及不良反应.三组样本间两两比较采用单因素方差分析LSD检验；计数资料采用x2检验.结果 A、B组各有1例因结肠镜诊断为恶性肿瘤伴肠腔狭窄而被剔除,其余113例患者均完成全结肠检查.三组患者基线资料差异无统计学意义(P＞0.05).C组患者各部分肠道及总体的清洁度评分均优于A、B组(总体清洁度评分:7.28±1.11比6.55±1.18、6.51±1.16,LSD检验,P均＜0.05)；C组排便次数亦多于A、B组(8.31±1.32比7.11±1.41、6.94±1.51,LSD检验,P均＜0.05)；三组肠道气泡,服药前后血压、心率、电解质,肠道准备的不适程度及不良反应发生率差异均无统计学意义(P均＞0.05).结论 结肠镜检查前1d及当天加用大剂量伊托必利能够安全有效地改善肠道准备效果.
目的 觀察促胃腸動力藥伊託必利在便祕患者結腸鏡檢查前腸道清潔中的作用.方法 將需要結腸鏡檢查的有慢性便祕史的門診連續病例115例納入研究,根據腸道準備方案分為3組:A組39例,檢查前6h服用標準劑量複方聚乙二醇電解質溶液；B組38例,口服A組洗腸液前30 min口服150 mg伊託必利；C組38例,檢查前1d上午7點、上午12點、下午8點各口服150 mg伊託必利,檢查噹天用藥同B組.三組患者用藥前後鑑測血壓、心率及電解質等.觀察各組患者腸道清潔度及不良反應.三組樣本間兩兩比較採用單因素方差分析LSD檢驗；計數資料採用x2檢驗.結果 A、B組各有1例因結腸鏡診斷為噁性腫瘤伴腸腔狹窄而被剔除,其餘113例患者均完成全結腸檢查.三組患者基線資料差異無統計學意義(P＞0.05).C組患者各部分腸道及總體的清潔度評分均優于A、B組(總體清潔度評分:7.28±1.11比6.55±1.18、6.51±1.16,LSD檢驗,P均＜0.05)；C組排便次數亦多于A、B組(8.31±1.32比7.11±1.41、6.94±1.51,LSD檢驗,P均＜0.05)；三組腸道氣泡,服藥前後血壓、心率、電解質,腸道準備的不適程度及不良反應髮生率差異均無統計學意義(P均＞0.05).結論 結腸鏡檢查前1d及噹天加用大劑量伊託必利能夠安全有效地改善腸道準備效果.
목적 관찰촉위장동력약이탁필리재편비환자결장경검사전장도청길중적작용.방법 장수요결장경검사적유만성편비사적문진련속병례115례납입연구,근거장도준비방안분위3조:A조39례,검사전6h복용표준제량복방취을이순전해질용액；B조38례,구복A조세장액전30 min구복150 mg이탁필리；C조38례,검사전1d상오7점、상오12점、하오8점각구복150 mg이탁필리,검사당천용약동B조.삼조환자용약전후감측혈압、심솔급전해질등.관찰각조환자장도청길도급불량반응.삼조양본간량량비교채용단인소방차분석LSD검험；계수자료채용x2검험.결과 A、B조각유1례인결장경진단위악성종류반장강협착이피척제,기여113례환자균완성전결장검사.삼조환자기선자료차이무통계학의의(P＞0.05).C조환자각부분장도급총체적청길도평분균우우A、B조(총체청길도평분:7.28±1.11비6.55±1.18、6.51±1.16,LSD검험,P균＜0.05)；C조배편차수역다우A、B조(8.31±1.32비7.11±1.41、6.94±1.51,LSD검험,P균＜0.05)；삼조장도기포,복약전후혈압、심솔、전해질,장도준비적불괄정도급불량반응발생솔차이균무통계학의의(P균＞0.05).결론 결장경검사전1d급당천가용대제량이탁필리능구안전유효지개선장도준비효과.
Objective To investigate the role of prokinetic agent itopride in colonic preparation before colonoscopy examination in patients with constipation.Methods A total of 115 outpatients with history of chronic constipation who requested colonoscopy were collected.According to colonic preparation proposal,patients were divided into three groups.Group A (39 cases) took standard dosage of PEG-E solution six hours before colonoscopy examination.Group B (38 cases) took 150 mg itopride 30 minutes before administration of lavage solution.Group C (38 cases) took itopride 150 mg at 7 am,12 am and 8 pm the day before the examination and on the examination day took the same medicine as that of group B.The blood pressure,heart rate and blood electrolytes were monitored before and after taking medicine in the patients of three groups.Quality of colon cleansing of each group was observed and side effects were also observed.One-way analysis of variance (least significant difference,LSD) test was performed for pairwise comparisons among the three groups.Chi-square test was applied for count data.Results Both group A and group B excluded one patient because of malignant carcinoma with colon stricture under colonoscopy,and 113 patients completed the whole colon examination.There was no significant difference in the baseline patients' data of three groups.The colon cleaning score of group C (7.28±1.11) was higher than those of group A and B (6.55±1.18 and 6.51±1.16,LSD test,both P＜0.05).The frequency of bowel movements defecation of group C (8.31± 1.32) was more than those of group A and group B (7.11± 1.41 and 6.94± 1.51,LSD,test,both P＜0.05).There was no significant difference in terms of intestinal bubble scores,blood pressure,heart rate,blood electrolytes the uncomfortable degree of colonic preparation and rate of side effects of the three groups.Conclusion The colonic preparation can be safely and effectively improved by taking high dose of itopride one day before and on the day of colonoscopy examination.
