CAJ | 학술논문

目的明确广东省中山市IBD的发病率及其临床特点.方法 2011年7月至2012年6月在广东省中山市开展以人群为基础的前瞻性IBD流行病学调查,纳入所有中山市户籍的新发IBD病例,统计其发病数、中国年龄标准化后发病率及临床特点.结果新发IBD患者48例,其中UC 31例,CD 17例.IBD标准化后发病率为3.14/10万,其中UC标准化后发病率为2.05/10万,CD标准化后发病率为1.09/10万.根据蒙特利尔分型,31例UC患者中,直肠炎11例(35.5％),左半结肠炎13例(41.9％),广泛结肠炎7例(22.6％).17例CD患者中,病变部位为回肠末端型4例(其中1例合并上消化道型),结肠型1例,回结肠型12例(其中3例合并上消化道型)；疾病行为是非狭窄非穿透型11例,狭窄型4例,穿透型2例.结论广东省中山市UC发病率为2.05/10万,CD发病率为1.09/10万.UC以左半结肠炎最常见,CD病变部位以回结肠型最常见.
목적 명학광동성중산시IBD적발병솔급기림상특점.방법 2011년7월지2012년6월재광동성중산시개전이인군위기출적전첨성IBD류행병학조사,납입소유중산시호적적신발IBD병례,통계기발병수、중국년령표준화후발병솔급림상특점.결과 신발IBD환자48례,기중UC 31례,CD 17례.IBD표준화후발병솔위3.14/10만,기중UC표준화후발병솔위2.05/10만,CD표준화후발병솔위1.09/10만.근거몽특리이분형,31례UC환자중,직장염11례(35.5％),좌반결장염13례(41.9％),엄범결장염7례(22.6％).17례CD환자중,병변부위위회장말단형4례(기중1례합병상소화도형),결장형1례,회결장형12례(기중3례합병상소화도형)；질병행위시비협착비천투형11례,협착형4례,천투형2례.결론 광동성중산시UC발병솔위2.05/10만,CD발병솔위1.09/10만.UC이좌반결장염최상견,CD병변부위이회결장형최상견.
Objective To investigate the incidence and clinical features of inflammatory bowel diseases (IBD) in Zhongshan City of Guangdong Province.Methods From July 2011 to June 2012,a prospective,population-based IBD epidemiological survey was conducted in Zhongshan City of Guangdong Province.All newly diagnosed IBD cases with Zhongshan census register were enrolled.The number of cases,Chinese age-standardized incidence and clinical features were analyzed.Results There were 48 new cases of IBD,of which 31 cases were ulcerative colitis (UC) and 17 cases were Crohn's disease (CD).The standardized incidence of IBD was 3.14/100 000,of which the incidence of UC was 2.05/100 000 and CD was 1.09/100 000.According to the Montreal classification,among 31 UC patients,11(35.5％) were proctitis,13 (41.9％) were left-sided colitis and seven (22.6％)were pancolitis.Among the 17 CD patients,lesions of four cases were terminal ileum type (one complicated with upper gastrointestinal bleeding),one case was colonic type and 12 cases were ileocolonic type (three cases complicated with upper gastrointestinal bleeding).Eleven cases were non-stricturing and non-penetrating type,four cases were stricturing type and two cases were penetrating type.Conclusions The incidence of UC is 2.05/100 000 and CD is 1.09/100 000 in Zhongshan City of Guangdong Province.Left-sided colitis is most common in UC and ileocolonic type is the most common in CD.