中华显微外科杂志
中華顯微外科雜誌
중화현미외과잡지
Chinese Journal of Microsurgery
2014年
4期
364-367
,共4页
卿黎明%唐举玉%杜威%王聪杨%俞芳%吴攀峰
卿黎明%唐舉玉%杜威%王聰楊%俞芳%吳攀峰
경려명%당거옥%두위%왕총양%유방%오반봉
腹壁浅动脉%穿支皮瓣%动物模型%移植%显微外科
腹壁淺動脈%穿支皮瓣%動物模型%移植%顯微外科
복벽천동맥%천지피판%동물모형%이식%현미외과
Superficial epigastric artery%Perforator flap%Animal model%Transplantation%Microsurgery
目的 探讨建立兔腹壁浅动脉穿支皮瓣游离移植实验模型的可行性. 方法 选择体质量2.5～3.0 kg的新西兰大耳白兔25只,雄雌不限.随机选取其中5只行局部解剖,以明确兔的腹壁浅动脉的起源、口径及其穿支的血供分布情况.余下的20只动物,根据腹壁浅动脉的血供分布情况,于动物腹部设计一面积6 cm×3 cm大小的腹壁浅动脉穿支皮瓣,采用股动静脉与颈总动脉、颈外静脉吻合构建腹壁浅动脉穿支皮瓣游离移植模型.供区均直接缝合. 结果 腹壁浅动脉发源于股动脉的近端,管径(0.15 ±0.02)mm,发出2～3支穿支供养下腹壁皮肤.构建实验模型的20只动物中,1只因麻醉意外死亡,余下实验动物均成功建立腹壁浅动脉穿支皮瓣游离移植模型,术后1例皮瓣出现静脉危象而坏死,其他皮瓣均顺利成活. 结论 利用新西兰大耳白兔可成功建立腹壁浅动脉穿支皮瓣游离移植的动物实验模型,该模型构建操作相对简单,成功率高.
目的 探討建立兔腹壁淺動脈穿支皮瓣遊離移植實驗模型的可行性. 方法 選擇體質量2.5～3.0 kg的新西蘭大耳白兔25隻,雄雌不限.隨機選取其中5隻行跼部解剖,以明確兔的腹壁淺動脈的起源、口徑及其穿支的血供分佈情況.餘下的20隻動物,根據腹壁淺動脈的血供分佈情況,于動物腹部設計一麵積6 cm×3 cm大小的腹壁淺動脈穿支皮瓣,採用股動靜脈與頸總動脈、頸外靜脈吻閤構建腹壁淺動脈穿支皮瓣遊離移植模型.供區均直接縫閤. 結果 腹壁淺動脈髮源于股動脈的近耑,管徑(0.15 ±0.02)mm,髮齣2～3支穿支供養下腹壁皮膚.構建實驗模型的20隻動物中,1隻因痳醉意外死亡,餘下實驗動物均成功建立腹壁淺動脈穿支皮瓣遊離移植模型,術後1例皮瓣齣現靜脈危象而壞死,其他皮瓣均順利成活. 結論 利用新西蘭大耳白兔可成功建立腹壁淺動脈穿支皮瓣遊離移植的動物實驗模型,該模型構建操作相對簡單,成功率高.
목적 탐토건립토복벽천동맥천지피판유리이식실험모형적가행성. 방법 선택체질량2.5～3.0 kg적신서란대이백토25지,웅자불한.수궤선취기중5지행국부해부,이명학토적복벽천동맥적기원、구경급기천지적혈공분포정황.여하적20지동물,근거복벽천동맥적혈공분포정황,우동물복부설계일면적6 cm×3 cm대소적복벽천동맥천지피판,채용고동정맥여경총동맥、경외정맥문합구건복벽천동맥천지피판유리이식모형.공구균직접봉합. 결과 복벽천동맥발원우고동맥적근단,관경(0.15 ±0.02)mm,발출2～3지천지공양하복벽피부.구건실험모형적20지동물중,1지인마취의외사망,여하실험동물균성공건립복벽천동맥천지피판유리이식모형,술후1례피판출현정맥위상이배사,기타피판균순리성활. 결론 이용신서란대이백토가성공건립복벽천동맥천지피판유리이식적동물실험모형,해모형구건조작상대간단,성공솔고.
Objective To explore the feasibility of building a new model of free superficial epigastric artery perforator flap with New Zealand white rabbits.Methods Twenty-five healthy New Zealand white rabbits were used.Five rabbits were dissected to assess the vascular territory,the source and dimension of the superficial epigastric.According to the anatomic results,the superficial epigastric artery perforator flap were designed and harvested with 6 cm× 3 cm in the abdominal,anastomosis had been done between femoral artery/vein and carotid artery,jugular venous to build an animal model of transplantation of epigastric artery perforator flap.The donor sites were directly closured.Results Superficial epigastric artery originated from the proximal femoral artery,and the diameter of superficial epigastric artery was (0.15 ±0.02) mm,2-3 perforators support the areas of the skin of the lower abdominal wall.A rabbit died in the surgery because of anesthesia,the other animals were alive.The results showed that all flaps were survived in the experiment except a flap lost due to venous crisis.Conclusion The experimental model of free superficial epigastric artery perforator flap can be built in New Zealand white rabbits.It is a simple,practical and reliable model for future physiologic and pharmacologic studies.
