中华心血管病杂志
中華心血管病雜誌
중화심혈관병잡지
Chinese Journal of Cardiology
2009年
9期
773-776
,共4页
伊宪华%韩雅玲%李毅%王守力%荆全民%马颖艳%王效增%栾波%王耿
伊憲華%韓雅玲%李毅%王守力%荊全民%馬穎豔%王效增%欒波%王耿
이헌화%한아령%리의%왕수력%형전민%마영염%왕효증%란파%왕경
冠状动脉疾病%动脉硬化%闭塞性%血管成形术%经腔%经皮冠状动脉%预后
冠狀動脈疾病%動脈硬化%閉塞性%血管成形術%經腔%經皮冠狀動脈%預後
관상동맥질병%동맥경화%폐새성%혈관성형술%경강%경피관상동맥%예후
Coronary disease%Arteriosclerosis obliterans%Angioplasty%transluminal%percutaneous coronary%Prognosis
目的 评价经皮冠状动脉介入治疗(PCI)成功开通冠状动脉慢性完全闭塞(CTO)病变对长期临床疗效的影响.方法 对1993年6月至2006年12月连续1332例冠状动脉CTO住院患者的临床资料进行分析.根据PCI结果将患者分为成功组(n=1202)和失败组(n=130),对比两组患者长期生存率、无主要不良心血管事件生存率及接受冠状动脉旁路移植术(CABG)的差别.结果 总病例成功率为90.2%(1202/1332),成功组患者PCI后10年生存率、无主要不良心血管事件生存率均明显高于失败组(分别为76.9%比64.6%,log rank P=0.012;41.8%比27.6%,log rank P<0.001),接受CABG患者则显著少于失败组(4.3%比14.6%,P<0.001).结论 PCI开通CTO病变可明显提高患者长期生存率和无主要不良心脏事件生存率,并减少对CABG的需求.
目的 評價經皮冠狀動脈介入治療(PCI)成功開通冠狀動脈慢性完全閉塞(CTO)病變對長期臨床療效的影響.方法 對1993年6月至2006年12月連續1332例冠狀動脈CTO住院患者的臨床資料進行分析.根據PCI結果將患者分為成功組(n=1202)和失敗組(n=130),對比兩組患者長期生存率、無主要不良心血管事件生存率及接受冠狀動脈徬路移植術(CABG)的差彆.結果 總病例成功率為90.2%(1202/1332),成功組患者PCI後10年生存率、無主要不良心血管事件生存率均明顯高于失敗組(分彆為76.9%比64.6%,log rank P=0.012;41.8%比27.6%,log rank P<0.001),接受CABG患者則顯著少于失敗組(4.3%比14.6%,P<0.001).結論 PCI開通CTO病變可明顯提高患者長期生存率和無主要不良心髒事件生存率,併減少對CABG的需求.
목적 평개경피관상동맥개입치료(PCI)성공개통관상동맥만성완전폐새(CTO)병변대장기림상료효적영향.방법 대1993년6월지2006년12월련속1332례관상동맥CTO주원환자적림상자료진행분석.근거PCI결과장환자분위성공조(n=1202)화실패조(n=130),대비량조환자장기생존솔、무주요불양심혈관사건생존솔급접수관상동맥방로이식술(CABG)적차별.결과 총병례성공솔위90.2%(1202/1332),성공조환자PCI후10년생존솔、무주요불양심혈관사건생존솔균명현고우실패조(분별위76.9%비64.6%,log rank P=0.012;41.8%비27.6%,log rank P<0.001),접수CABG환자칙현저소우실패조(4.3%비14.6%,P<0.001).결론 PCI개통CTO병변가명현제고환자장기생존솔화무주요불양심장사건생존솔,병감소대CABG적수구.
Objective To evaluate the long-term outcomes of successful or failed revaacularization in patients with chronic total occlusions (CTO). Methods The clinical data of 1332 consecutive patients underwent percutaneous coronary intervention (PCI) for CTO between June 1993 and December 2006 in our hospital were analyzed. These patients were divided into two groups according to the procedural success (n= 1202) or failure (n=130). Results Overall success rate of procedure was 90. 2% (1202/1332). The patients in CTO success group experienced a superior 10-year survival rate (76.9% vs. 64.6%, log rank P=0.012) and a significantly higher no major adverse cardiovascular event(MACE) survival rate (41.8% vs. 27.6%, log rank P < 0.001) compared to the patients in CTO failure group. During the long-term follow-up, the proportion of patients who accepted coronary artery bypass grafting(CABG) was significantly lower in CTO success group than that in the CTO failure group (4.3% vs. 14.6% ,P <0.001). Conclusion Successful PCI procedure leads to increased long-term survival and MACE-free survival and the reduced need for CABG for patients with CTO lesions.
