CAJ | 학술논문

目的对比腺苷负荷核素心肌灌注成像结果,探讨静息状态下CT心肌首过灌注成像检测心肌缺血的可行性与准确性.方法 22例怀疑或诊断为冠心病的患者,在2周内完成CT冠状动脉造影(CTCA)和腺苷负荷/静息核素心肌灌注成像(MPS)检查.应用CTCA的原始数据进行CT心肌首过灌注成像分析,以腺苷负荷/静息MPS结果为参照,评价CT心肌首过灌注成像检测心肌缺血的准确性.结果以MPS结果作为参照,CT心肌首过灌注成像检测心肌缺血的敏感性为92％(12/13),特异性为78％ (7/9),阳性预测值为86％ (12/14),阴性预测值为88％ (7/8),准确性为86％ (19/22).2种检查方法在检出率上差异无统计学意义(P＞0.05).结论静息状态下CT心肌首过灌注成像评价心肌灌注的方法临床可行,且对检测心肌缺血有着较高的准确性.
목적 대비선감부하핵소심기관주성상결과,탐토정식상태하CT심기수과관주성상검측심기결혈적가행성여준학성.방법 22례부의혹진단위관심병적환자,재2주내완성CT관상동맥조영(CTCA)화선감부하/정식핵소심기관주성상(MPS)검사.응용CTCA적원시수거진행CT심기수과관주성상분석,이선감부하/정식MPS결과위삼조,평개CT심기수과관주성상검측심기결혈적준학성.결과 이MPS결과작위삼조,CT심기수과관주성상검측심기결혈적민감성위92％(12/13),특이성위78％ (7/9),양성예측치위86％ (12/14),음성예측치위88％ (7/8),준학성위86％ (19/22).2충검사방법재검출솔상차이무통계학의의(P＞0.05).결론 정식상태하CT심기수과관주성상평개심기관주적방법림상가행,차대검측심기결혈유착교고적준학성.
Objective To assess the feasibility and accuracy of CT first-pass myocardial perfusion imaging (CT first-pass MPI) at rest for diagnosis of myocardial ischemia.Results of adenosine-induced myocardial perfusion scintigraphy (MPS) were used as gold standard.Methods Twenty-two patients with suspected or diagnosed coronary artery disease (CAD) were included and CT coronary angiography (CTCA) and MPS were performed within 2 weeks.CT first-pass MPI detected myocardial ischemia results through analyzing the raw date of CTCA were compared with MPS results.Results The sensibility,specificity,positive predictive value (PPV),negative predictive value (NPV) and accuracy of CT first-pass MPI at rest for detecting myocardial ischemia were 92％ (12/13),78％ (7/9),86％ (12/14),88％ (7/8) and 86％(19/22),respectively.Conclusion CT first-pass MPI at rest could detect myocardial ischemia with an accuracy similar to that of MPS.