中华心血管病杂志
中華心血管病雜誌
중화심혈관병잡지
Chinese Journal of Cardiology
2013年
5期
390-393
,共4页
王骄%陈一川%杜华安%李晓丽%梅霞%殷跃辉
王驕%陳一川%杜華安%李曉麗%梅霞%慇躍輝
왕교%진일천%두화안%리효려%매하%은약휘
心房颤动%肾功能衰竭,慢性%透析
心房顫動%腎功能衰竭,慢性%透析
심방전동%신공능쇠갈,만성%투석
Atrial fibrillation%Kidney failure,chronic%Dialysis
目的 心房颤动(房颤)是普通人群中最常见的持续性心律失常,其与慢性肾脏疾病(CKD)具有一些共同的危险因素,探讨我国CKD与罹患房颤的关系.方法 1168例CKD住院患者被纳入研究,平均年龄(63.3±14.2)岁,男性占54.5％.房颤由心电图或既往确切病史判定.比较不同年龄、性别及估算肾小球滤过率(eGFR)各亚组房颤的患病率.多元logistic回归分析与房颤发生的关联因素.结果 平均eGFR为(22.2±19.7) ml·min-1·1.73 m-2,84.2％的研究对象eGFR≤45 ml·min-1·1.73 m-2,38.5％的为血液透析患者.60岁以上的患者占66.9％,房颤患病率为17.2％.与eGFR＞45 ml· min-1· 1.73 m-2患者相比,eGFR≤45 ml·min-1·1.73 m-2患者房颤的患病率更高(15.8％比5.4％,P＜0.001).多元logistic回归分析显示年龄、体质指数、心力衰竭、左房前后径、eGFR和透析与房颤发生显著相关；性别、吸烟、高血压、糖尿病与房颤无显著相关性.结论 年龄、体质指数、心力衰竭、左心房径、eGFR和透析与房颤显著相关.
目的 心房顫動(房顫)是普通人群中最常見的持續性心律失常,其與慢性腎髒疾病(CKD)具有一些共同的危險因素,探討我國CKD與罹患房顫的關繫.方法 1168例CKD住院患者被納入研究,平均年齡(63.3±14.2)歲,男性佔54.5％.房顫由心電圖或既往確切病史判定.比較不同年齡、性彆及估算腎小毬濾過率(eGFR)各亞組房顫的患病率.多元logistic迴歸分析與房顫髮生的關聯因素.結果 平均eGFR為(22.2±19.7) ml·min-1·1.73 m-2,84.2％的研究對象eGFR≤45 ml·min-1·1.73 m-2,38.5％的為血液透析患者.60歲以上的患者佔66.9％,房顫患病率為17.2％.與eGFR＞45 ml· min-1· 1.73 m-2患者相比,eGFR≤45 ml·min-1·1.73 m-2患者房顫的患病率更高(15.8％比5.4％,P＜0.001).多元logistic迴歸分析顯示年齡、體質指數、心力衰竭、左房前後徑、eGFR和透析與房顫髮生顯著相關；性彆、吸煙、高血壓、糖尿病與房顫無顯著相關性.結論 年齡、體質指數、心力衰竭、左心房徑、eGFR和透析與房顫顯著相關.
목적 심방전동(방전)시보통인군중최상견적지속성심률실상,기여만성신장질병(CKD)구유일사공동적위험인소,탐토아국CKD여리환방전적관계.방법 1168례CKD주원환자피납입연구,평균년령(63.3±14.2)세,남성점54.5％.방전유심전도혹기왕학절병사판정.비교불동년령、성별급고산신소구려과솔(eGFR)각아조방전적환병솔.다원logistic회귀분석여방전발생적관련인소.결과 평균eGFR위(22.2±19.7) ml·min-1·1.73 m-2,84.2％적연구대상eGFR≤45 ml·min-1·1.73 m-2,38.5％적위혈액투석환자.60세이상적환자점66.9％,방전환병솔위17.2％.여eGFR＞45 ml· min-1· 1.73 m-2환자상비,eGFR≤45 ml·min-1·1.73 m-2환자방전적환병솔경고(15.8％비5.4％,P＜0.001).다원logistic회귀분석현시년령、체질지수、심력쇠갈、좌방전후경、eGFR화투석여방전발생현저상관；성별、흡연、고혈압、당뇨병여방전무현저상관성.결론 년령、체질지수、심력쇠갈、좌심방경、eGFR화투석여방전현저상관.
Objective Atrial fibrillation (AF) is the most common sustained tachyarrhythmia in the general population.AF and Chronic Kidney Disease (CKD) share several common risk factors.We investigated the association between chronic kidney disease and risk of atrial fibrillation in hospitalized patients with CKD.Methods One thousand one hundred and sixty-eight patients [(63.3 ± 14.2) years,54.5％ males] hospitalized CKD patients were included.AF was determined by electrocardiogram or medical history.The prevalence of atrial fibrillation was compared in CKD patients with various age,sex and glomerular filtration rate (eGFR).Binary logistic regression analysis was used to determine the risk factors of AF.Result The mean eGFR was (22.2 ± 19.7)ml · min-1 · 1.73 m-2 ; eGFR was ≤45 ml · min-1 1.73 m-2 in 84.2％ patients and 38.5％ patients received hemodialysis.AF was present in 14.2％ of the study population and 17.2％ in patients ≥60 years old.Prevalence of AF was significantly higher in patients with eGFR≤45 ml· min-1 · 1.73 m-2 compared patients with eGFR ＞45 ml· min-1 · 1.73 m-2(15.8％vs.5.4％,P ＜ 0.001).Binary logistic regression analysis showed that age,body mass index (BMI),heart failure (HF),left atrial diameter (LAD),eGFR and dialysis were independent risk factors for AF.Conclusions AF is much more frequent in CKD patients than in the general population.Age,BMI,HF,LAD,eGFR and dialysis are risk factors for AF in hospitalized patients with CKD.
