中华胸心血管外科杂志
中華胸心血管外科雜誌
중화흉심혈관외과잡지
Chinese Journal of Thoracic and Cardiovascular Surgery
2014年
10期
586-589
,共4页
陈晓博%何少茹%庄建%钟劲%孙新%刘玉梅%孙云霞%郑曼利%陈寄梅
陳曉博%何少茹%莊建%鐘勁%孫新%劉玉梅%孫雲霞%鄭曼利%陳寄梅
진효박%하소여%장건%종경%손신%류옥매%손운하%정만리%진기매
室间隔缺损%心脏外科手术%血流动力学%肌力指数%婴儿
室間隔缺損%心髒外科手術%血流動力學%肌力指數%嬰兒
실간격결손%심장외과수술%혈류동역학%기력지수%영인
Ventricular septal defect%Cardiac surgical procedures%Hemodynamics%Inotropy index%Infants
目的 无创快速评估小婴儿室间隔缺损(VSD)修补术后早期肌力指数的改变,指导临床合理用药.方法 采用超声心输出量监测仪(USCOM)观察VSD修补术后1～2周小婴儿的血流动力学指标,以同龄健康小婴儿为对照.结果 两组小婴儿各50例,月龄中位数为3个月,VSD术后组的肌力指数(SMII)明显高于健康对照组[(1.4±0.4)对(1.1±0.2)W/m2,P＜0.01];每搏指数和每公斤心输出量均较健康对照组明显偏高(P＜0.05),收缩期血液流动时间较健康对照组明显缩短(P＜0.01).结论 小婴儿VSD修补术后早期,循环功能各项指标尚未完全恢复至正常水平,有待后期随访监测.肌力指数直接反映心肌功能,可能在术后随访用药中有重要的临床指导意义.
目的 無創快速評估小嬰兒室間隔缺損(VSD)脩補術後早期肌力指數的改變,指導臨床閤理用藥.方法 採用超聲心輸齣量鑑測儀(USCOM)觀察VSD脩補術後1～2週小嬰兒的血流動力學指標,以同齡健康小嬰兒為對照.結果 兩組小嬰兒各50例,月齡中位數為3箇月,VSD術後組的肌力指數(SMII)明顯高于健康對照組[(1.4±0.4)對(1.1±0.2)W/m2,P＜0.01];每搏指數和每公斤心輸齣量均較健康對照組明顯偏高(P＜0.05),收縮期血液流動時間較健康對照組明顯縮短(P＜0.01).結論 小嬰兒VSD脩補術後早期,循環功能各項指標尚未完全恢複至正常水平,有待後期隨訪鑑測.肌力指數直接反映心肌功能,可能在術後隨訪用藥中有重要的臨床指導意義.
목적 무창쾌속평고소영인실간격결손(VSD)수보술후조기기력지수적개변,지도림상합리용약.방법 채용초성심수출량감측의(USCOM)관찰VSD수보술후1～2주소영인적혈류동역학지표,이동령건강소영인위대조.결과 량조소영인각50례,월령중위수위3개월,VSD술후조적기력지수(SMII)명현고우건강대조조[(1.4±0.4)대(1.1±0.2)W/m2,P＜0.01];매박지수화매공근심수출량균교건강대조조명현편고(P＜0.05),수축기혈액류동시간교건강대조조명현축단(P＜0.01).결론 소영인VSD수보술후조기,순배공능각항지표상미완전회복지정상수평,유대후기수방감측.기력지수직접반영심기공능,가능재술후수방용약중유중요적림상지도의의.
Objective To evaluate inotropy index(SMII) in infants early after surgical repair of ventricular septal defect (VSD),which could guide rational clinical treatment.Methods This was a prospective and observational study.Subjects were infants 1-2 weeks after VSD repair,along with age-matched healthy infants as the control group.Hemodynamic parameters were measured using ultrasonic cardiac output monitor(USCOM),respectively.Results There were 50 subjects in both groups,representing the same age distribution 1 and 6 (median 3) months.In VSD postoperative group,the SMII was significantly higher than the control group [(1.4 ± 0.4) vs.(1.1 ± 0.2) W/m2,P ＜ 0.01],stroke index and cardiac output per kilogram were significantly higher than those in control group (P ＜ 0.05),and systolic blood flow time was significantly shorter than the control group (P ＜ 0.01).Conclusion For infants undergone VSD repair,the circulatory function was not fully recovered to normal level at early postoperation,pending long-term follow-up.Inotropy index directly reflects myocardial function,may play an important role in guiding medication in the postoperative follow-up.
