中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2013年
12期
1122-1127
,共6页
毛光明%丁钢强%楼晓明%朱文明%王晓峰%莫哲%周金水
毛光明%丁鋼彊%樓曉明%硃文明%王曉峰%莫哲%週金水
모광명%정강강%루효명%주문명%왕효봉%막철%주금수
碘%水碘%盐碘%弥漫性甲状腺肿大
碘%水碘%鹽碘%瀰漫性甲狀腺腫大
전%수전%염전%미만성갑상선종대
Iodine%Water iodine%Salt iodine%Diffuse goiter
目的 了解2010年浙江省弥漫性甲状腺肿患病状况并分析其影响因素.方法 2010年4月在浙江省采用多阶段分层整群随机抽样方法进行横断面调查,对浙江省18 188名对象进行甲状腺容积B超测量,并通过问卷调查居民基本状况和生活习惯,对弥漫性甲状腺肿患病状况的分布及其相关性进行分析.结果 调查人群弥漫性甲状腺肿大率为2.2％(403/18 188),不同年龄组人群肿大率差别有统计学意义(x2=267.11,P＜0.05),其中6～7岁、8～10岁年龄组肿大率较高,分别为10.3％(27/262)、9.8％ (51/519);女性肿大率(2.9％,305/10 470)高于男性的(1.3％,97/7672)(x2=55.55,P＜0.05);内陆地区肿大率最高(3.2％,138/4374),次沿海次之(2.0％,131/6411),沿海地区最低(1.8％,138/4374)(x2=24.31,P＜0.05).甲状腺肿大人群与正常组人群对应的水碘含量[甲状腺肿大人群中位数(四分位数区间):1.88(1.49 ～5.15) μg/L;正常人群:2.41(1.96 ～6.15) μg/L]和盐碘含量[甲状腺肿大人群:29.1(24.70 ～ 31.95) mg/kg;正常人群:30.18(24.69 ～ 32.65) mg/kg]比较差异有统计学意义(水碘:x2=4.95,P=0.026;盐碘:x2=11.03,P＜0.01).对甲状腺肿大的相关因素分析结果显示家庭收入、文化程度、就业状况、职业种类、饮食特点、是否常吃海产品、饮酒情况与甲状腺肿大有关(x2值分别为8.08、37.85、98.78、68.69、10.91、12.21、26.94,P均＜0.05).多因素分析可知,女性(OR=0.27,95％CI:0.18 ～0.39)、在校学生(OR=8.05,95％ CI:3.87～16.73)、素食为主(OR=1.60,95％CI:1.15 ～2.22)患甲状腺肿大风险较高;文化程度为大学及以上(OR=0.84,95％CI:0.73～0.97)、常吃海产品(OR=0.62,95％ CI:0.44～0.88)患甲状腺肿大风险较低.结论 浙江省6～7岁和8 ～10岁年龄组弥漫性甲状腺肿率较高.甲状腺肿大患病率受很多因素影响.
目的 瞭解2010年浙江省瀰漫性甲狀腺腫患病狀況併分析其影響因素.方法 2010年4月在浙江省採用多階段分層整群隨機抽樣方法進行橫斷麵調查,對浙江省18 188名對象進行甲狀腺容積B超測量,併通過問捲調查居民基本狀況和生活習慣,對瀰漫性甲狀腺腫患病狀況的分佈及其相關性進行分析.結果 調查人群瀰漫性甲狀腺腫大率為2.2％(403/18 188),不同年齡組人群腫大率差彆有統計學意義(x2=267.11,P＜0.05),其中6～7歲、8～10歲年齡組腫大率較高,分彆為10.3％(27/262)、9.8％ (51/519);女性腫大率(2.9％,305/10 470)高于男性的(1.3％,97/7672)(x2=55.55,P＜0.05);內陸地區腫大率最高(3.2％,138/4374),次沿海次之(2.0％,131/6411),沿海地區最低(1.8％,138/4374)(x2=24.31,P＜0.05).甲狀腺腫大人群與正常組人群對應的水碘含量[甲狀腺腫大人群中位數(四分位數區間):1.88(1.49 ～5.15) μg/L;正常人群:2.41(1.96 ～6.15) μg/L]和鹽碘含量[甲狀腺腫大人群:29.1(24.70 ～ 31.95) mg/kg;正常人群:30.18(24.69 ～ 32.65) mg/kg]比較差異有統計學意義(水碘:x2=4.95,P=0.026;鹽碘:x2=11.03,P＜0.01).對甲狀腺腫大的相關因素分析結果顯示傢庭收入、文化程度、就業狀況、職業種類、飲食特點、是否常喫海產品、飲酒情況與甲狀腺腫大有關(x2值分彆為8.08、37.85、98.78、68.69、10.91、12.21、26.94,P均＜0.05).多因素分析可知,女性(OR=0.27,95％CI:0.18 ～0.39)、在校學生(OR=8.05,95％ CI:3.87～16.73)、素食為主(OR=1.60,95％CI:1.15 ～2.22)患甲狀腺腫大風險較高;文化程度為大學及以上(OR=0.84,95％CI:0.73～0.97)、常喫海產品(OR=0.62,95％ CI:0.44～0.88)患甲狀腺腫大風險較低.結論 浙江省6～7歲和8 ～10歲年齡組瀰漫性甲狀腺腫率較高.甲狀腺腫大患病率受很多因素影響.
목적 료해2010년절강성미만성갑상선종환병상황병분석기영향인소.방법 2010년4월재절강성채용다계단분층정군수궤추양방법진행횡단면조사,대절강성18 188명대상진행갑상선용적B초측량,병통과문권조사거민기본상황화생활습관,대미만성갑상선종환병상황적분포급기상관성진행분석.결과 조사인군미만성갑상선종대솔위2.2％(403/18 188),불동년령조인군종대솔차별유통계학의의(x2=267.11,P＜0.05),기중6～7세、8～10세년령조종대솔교고,분별위10.3％(27/262)、9.8％ (51/519);녀성종대솔(2.9％,305/10 470)고우남성적(1.3％,97/7672)(x2=55.55,P＜0.05);내륙지구종대솔최고(3.2％,138/4374),차연해차지(2.0％,131/6411),연해지구최저(1.8％,138/4374)(x2=24.31,P＜0.05).갑상선종대인군여정상조인군대응적수전함량[갑상선종대인군중위수(사분위수구간):1.88(1.49 ～5.15) μg/L;정상인군:2.41(1.96 ～6.15) μg/L]화염전함량[갑상선종대인군:29.1(24.70 ～ 31.95) mg/kg;정상인군:30.18(24.69 ～ 32.65) mg/kg]비교차이유통계학의의(수전:x2=4.95,P=0.026;염전:x2=11.03,P＜0.01).대갑상선종대적상관인소분석결과현시가정수입、문화정도、취업상황、직업충류、음식특점、시부상흘해산품、음주정황여갑상선종대유관(x2치분별위8.08、37.85、98.78、68.69、10.91、12.21、26.94,P균＜0.05).다인소분석가지,녀성(OR=0.27,95％CI:0.18 ～0.39)、재교학생(OR=8.05,95％ CI:3.87～16.73)、소식위주(OR=1.60,95％CI:1.15 ～2.22)환갑상선종대풍험교고;문화정도위대학급이상(OR=0.84,95％CI:0.73～0.97)、상흘해산품(OR=0.62,95％ CI:0.44～0.88)환갑상선종대풍험교저.결론 절강성6～7세화8 ～10세년령조미만성갑상선종솔교고.갑상선종대환병솔수흔다인소영향.
Objective To evaluate the status of diffuse goiter of population in Zhejiang Province and to analyze the relevant influencing factors.Methods A total of 18 188 subjects were recruited in the cross sectional survey,by multistage stratified cluster random sampling method.B ultrasound measurement were carried among the subjects to detect the thyroid volume,and the basic information and life styles were interviewed by questionnaires.Then,we analyzed the distribution and its influencing factors of diffuse goiter.Results The ratio of diffuse goiter among the surveyed population was 2.2％ (403/18 188),the difference showed statistical significance (x2 =267.11,P ＜ 0.05).The ratio among the group aged 6-7 years old and 8-10 years old was comparatively high,separately 10.3％ (27/262) and 9.8％ (51/519).The ratio among women (2.9％,305/10 470) was higher than it among men (1.3％,97/7672) (x2 =55.55,P ＜ 0.05).The residents from inland areas had the highest prevalence (3.2％,138/4374),followed by residents from sub-coastal areas (2.0％,131/6411),coastal areas minimum (1.8％,138/4374) (x2 =24.31,P ＜ 0.05).The content of water iodine and salt iodine among people with symptoms of goiter had statistical difference with it among ordinary population (water iodine:x2 =4.95,P =0.026 ; salt iodine:x2 =11.03,P ＜ 0.01).The median (quartile) of water iodine in ordinary population was 2.41 (1.96-6.15) μg/L and among people with symptoms of goiter was 1.88 (1.49-5.15) μg/L.The median (quartile) of salt iodine in ordinary population was 30.18 (24.69-32.65) mg/kg and among people with symptoms of goiter was 29.1 (24.70-31.95) mg/kg.The influential factors of goiter were as follows:the family income,the education degree,the job and profession status,the diet character,the habitual sea food consumption,the alcohol intake status (x2 were separately 8.08,37.85,98.78,68.69,10.91,12.21,26.94,P ＜ 0.05).Multi-factor analysis showed the results as follows:female (OR =0.27 95％ CI:0.18-0.39),school students (OR =8.05,95％ CI:3.87-16.73),vegetarian (OR =1.60,95％ CI:1.15-2.22) took a higher risk of getting pathogenic goiter; while the group of those who had university degree or above (OR =0.84,95％ CI:0.73-0.97),ate sea food frequently (OR =0.62,95％ CI:0.44-0.88) took a lower risk.Conclusions The ratio of diffuse goiter in the group aged among 6-7 years old and 8-10 years old was comparatively high.The ratio was influenced by many factors.
