中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2014年
5期
380-385
,共6页
潘晓红%陈琳%徐云%夏燕%郭志宏%杨介者
潘曉紅%陳琳%徐雲%夏燕%郭誌宏%楊介者
반효홍%진림%서운%하연%곽지굉%양개자
HIV%获得性免疫缺陷综合征%影响因素%横断面研究
HIV%穫得性免疫缺陷綜閤徵%影響因素%橫斷麵研究
HIV%획득성면역결함종합정%영향인소%횡단면연구
HIV%Acquired immunodeficiency syndrome%Influence factors%Cross-sectional studies
目的 调查2012年浙江省新确诊HIV感染者和艾滋病患者HIV检测发现及时性状况及其可能的影响因素.方法 利用全国艾滋病综合防治信息系统数据库,收集2012年浙江省所有县(市、区)新确诊且确诊后1个月内做过CD4+T淋巴细胞检测的HIV感染者和艾滋病患者个案信息,包括社会人口学特征、感染途径、检测类型和检测单位类别、常住地等,共1 894例研究对象纳入本研究,其中,对1 383例研究对象进行了BED HIV-1捕获酶联检测.首次检测CD4+T淋巴细胞＜200个/μl者判定为迟发现,BED HIV-1捕获酶联检测结果阳性者判定为早发现.使用x2检验和多元logistic回归进行单因素和多因素统计学分析,获得HIV感染者和艾滋病患者的HIV检测发现特征及相关影响因素.结果 1 894例研究对象中,迟发现率为26.4％ (500/1 894),早发现率为19.2％ (361/1 883).地区分布以丽水市迟发现比例最高(36.5％,27/74),早发现比例最低(3.9％,14/74).单因素和多因素logistic回归分析表明,年龄、感染途径、检测类型、常住地是研究对象HIV检测迟发现的独立影响因素.年龄≥50岁者HIV检测迟发现率是年龄＜20岁的2.885倍(OR=2.885,P＜0.05);异性性接触者和其他途径传播者HIV检测迟发现率分别是男男同性性接触者的1.471、2.416倍(OR=1.471、2.416,P＜0.05);HIV检测早发现状况与年龄、婚姻状况、感染途径、检测单位类别及常住地有关.年龄≥50岁者HIV检测早发现率是年龄＜20岁以下者的0.432倍(OR=0.432,P＜0.05);婚姻状况为已婚者早发现率低于未婚者(OR=0.603,P＜0.05);与男男同性性接触者相比,异性性接触和其他途径传播者早发现率均较低(0R=0.719、0.763,P＜0.05);通过社会卫生服务中心和医院检测发现者早发现率均低于CDC发现者(OR=0.621、0.663,P＜0.05).结论 HIV感染者和艾滋病患者存在迟发现和早发现并存的现象,年龄大、非同性传播、医院其他就诊者检测、常住地为外省是HIV检测迟发现的主要原因,年龄小、未婚、同性传播、CDC检测、常住本省城区者是HIV检测早发现的主要因素.
目的 調查2012年浙江省新確診HIV感染者和艾滋病患者HIV檢測髮現及時性狀況及其可能的影響因素.方法 利用全國艾滋病綜閤防治信息繫統數據庫,收集2012年浙江省所有縣(市、區)新確診且確診後1箇月內做過CD4+T淋巴細胞檢測的HIV感染者和艾滋病患者箇案信息,包括社會人口學特徵、感染途徑、檢測類型和檢測單位類彆、常住地等,共1 894例研究對象納入本研究,其中,對1 383例研究對象進行瞭BED HIV-1捕穫酶聯檢測.首次檢測CD4+T淋巴細胞＜200箇/μl者判定為遲髮現,BED HIV-1捕穫酶聯檢測結果暘性者判定為早髮現.使用x2檢驗和多元logistic迴歸進行單因素和多因素統計學分析,穫得HIV感染者和艾滋病患者的HIV檢測髮現特徵及相關影響因素.結果 1 894例研究對象中,遲髮現率為26.4％ (500/1 894),早髮現率為19.2％ (361/1 883).地區分佈以麗水市遲髮現比例最高(36.5％,27/74),早髮現比例最低(3.9％,14/74).單因素和多因素logistic迴歸分析錶明,年齡、感染途徑、檢測類型、常住地是研究對象HIV檢測遲髮現的獨立影響因素.年齡≥50歲者HIV檢測遲髮現率是年齡＜20歲的2.885倍(OR=2.885,P＜0.05);異性性接觸者和其他途徑傳播者HIV檢測遲髮現率分彆是男男同性性接觸者的1.471、2.416倍(OR=1.471、2.416,P＜0.05);HIV檢測早髮現狀況與年齡、婚姻狀況、感染途徑、檢測單位類彆及常住地有關.年齡≥50歲者HIV檢測早髮現率是年齡＜20歲以下者的0.432倍(OR=0.432,P＜0.05);婚姻狀況為已婚者早髮現率低于未婚者(OR=0.603,P＜0.05);與男男同性性接觸者相比,異性性接觸和其他途徑傳播者早髮現率均較低(0R=0.719、0.763,P＜0.05);通過社會衛生服務中心和醫院檢測髮現者早髮現率均低于CDC髮現者(OR=0.621、0.663,P＜0.05).結論 HIV感染者和艾滋病患者存在遲髮現和早髮現併存的現象,年齡大、非同性傳播、醫院其他就診者檢測、常住地為外省是HIV檢測遲髮現的主要原因,年齡小、未婚、同性傳播、CDC檢測、常住本省城區者是HIV檢測早髮現的主要因素.
목적 조사2012년절강성신학진HIV감염자화애자병환자HIV검측발현급시성상황급기가능적영향인소.방법 이용전국애자병종합방치신식계통수거고,수집2012년절강성소유현(시、구)신학진차학진후1개월내주과CD4+T림파세포검측적HIV감염자화애자병환자개안신식,포괄사회인구학특정、감염도경、검측류형화검측단위유별、상주지등,공1 894례연구대상납입본연구,기중,대1 383례연구대상진행료BED HIV-1포획매련검측.수차검측CD4+T림파세포＜200개/μl자판정위지발현,BED HIV-1포획매련검측결과양성자판정위조발현.사용x2검험화다원logistic회귀진행단인소화다인소통계학분석,획득HIV감염자화애자병환자적HIV검측발현특정급상관영향인소.결과 1 894례연구대상중,지발현솔위26.4％ (500/1 894),조발현솔위19.2％ (361/1 883).지구분포이려수시지발현비례최고(36.5％,27/74),조발현비례최저(3.9％,14/74).단인소화다인소logistic회귀분석표명,년령、감염도경、검측류형、상주지시연구대상HIV검측지발현적독립영향인소.년령≥50세자HIV검측지발현솔시년령＜20세적2.885배(OR=2.885,P＜0.05);이성성접촉자화기타도경전파자HIV검측지발현솔분별시남남동성성접촉자적1.471、2.416배(OR=1.471、2.416,P＜0.05);HIV검측조발현상황여년령、혼인상황、감염도경、검측단위유별급상주지유관.년령≥50세자HIV검측조발현솔시년령＜20세이하자적0.432배(OR=0.432,P＜0.05);혼인상황위이혼자조발현솔저우미혼자(OR=0.603,P＜0.05);여남남동성성접촉자상비,이성성접촉화기타도경전파자조발현솔균교저(0R=0.719、0.763,P＜0.05);통과사회위생복무중심화의원검측발현자조발현솔균저우CDC발현자(OR=0.621、0.663,P＜0.05).결론 HIV감염자화애자병환자존재지발현화조발현병존적현상,년령대、비동성전파、의원기타취진자검측、상주지위외성시HIV검측지발현적주요원인,년령소、미혼、동성전파、CDC검측、상주본성성구자시HIV검측조발현적주요인소.
Objective To assess the characteristics and influencing factors of HIV detection among HIV/AIDS patients in Zhejiang province.Methods HIV/AIDS cases information were selected from the case reporting database of HIV/AIDS Comprehensive Response Information Management System in Zhejiang province in 2012.HIV late diagnosed patients and early diagnosed patients were classified by first CD4 + T cell counts (less than 200 cells/μl) and positive BED HIV-1 capture enzyme immunoassay (BED-CEIA) tests result.A total of 1 894 patients were enrolled and 1 383 patients were served by BED-CEIA tests.Information including social demographics,transmission routes,testhistory were collected for analysis.The univariate and multivariate logistic regression methods was used to analyze the characteristics of HIV detection and related influence factors.Results Among 1 894 cases,26.4％ (500/1 894) were late diagnosed and 19.2％ (361/1 883) were early diagnosed.The highest rate of late diagnose (36.5％,27/74) and lowest rate of early diagnose (3.9％,14/74) were both in Lishui city.Age,transmission routes,HIV testing style,permanent residence were independent reasons for late diagnosed.Compared with patients ＜ 20 years old,participants over 50 years old had higher risk of late diagnosed (OR =2.885,P ＜0.05) ; patients with homosexual behaviors had lower risk of late diagnosed than patients with heterosexual behaviors and other high risk behaviors (OR =1.471 or 2.416,P ＜ 0.05).Age,marriage status,HIV testing style,transmission routes,the detection unit,permanent residence were independent reasons for early diagnosed.The risky of early diagnosed among patients ≥ 50 years old were 0.432 times than that among patients ＜ 20 years old (OR =0.432,P ＜ 0.05).Compared with unmarried participants,married patients had lower risk of early diagnosed (OR =0.603,P ＜ 0.05).Compared with homosexual behaviors,high risk heterosexual behaviors and other risk behavior significantly reduced the chance of early diagnosis (OR =0.719 or 0.763,P ＜ 0.05).Conclusion Late diagnoses and early diagnosis coexist among reported HIV/AIDS in Zhejiang province in 2012.The main reasons for late diagnosis of HIV infection are older age,heterosexual behaviors and other risk behavior,testing in hospital,living in other province.The main reasons for early diagnosis of HIV infection are young age,unmarried,homosexual behaviors,testing in CDC,living in Zhejiang province.
