CAJ | 학술논문

目的分析1998-2010年北京市户籍居民恶性淋巴瘤(简称淋巴瘤)发病特点及流行趋势.方法统计北京市肿瘤登记处1998-2010年淋巴瘤发病病例,共计9 763例,覆盖人口151 601 066人年.计算年度发病率,中国人口结构标化率(简称中标率),世界人口构成标化率(简称世标率)以及年度平均变化率(APC),累积发病率和截缩率.分析不同性别、年龄、地区人群的淋巴瘤的发病率趋势.结果 1998-2010年北京市淋巴瘤发病率为6.48/10万(9 763/150 720 187),由1998年的3.78/10万(410/10 850 626)上升至2010年的8.88/10万(1 111/12 518 114),增长了136.17％,世标率的APC为5.21％(P＜0.05);霍奇金淋巴瘤发病率由1998年的0.25/10万(27/10 850 626)上升至2010年的0.47/10万(59/12 518 114),增长了88.00％,世标率的APC为4.33％ (P ＜0.05);非霍奇金淋巴瘤发病率由1998年的2.89/10万(314/10 850 626)上升至2010年的5.93/10万(742/12 518 114),增长了105.19％,世标发病率的APC为4.19％ (P ＜0.05).1998-2010年北京城区淋巴瘤发病率为7.78/10万(7 125/91 621 898),郊区发病率为4.47/10万(2 638/59 098 289),城郊发病率比为1.74;男性发病率为7.40/10万(5 632/76 121 672),女性为5.54/10万(4 131/74 598 518).结论 1998-2010年北京市淋巴瘤发病率逐年增高,男性高于女性,城区高于郊区,霍奇金淋巴瘤与非霍奇金淋巴瘤的发病率不同.
목적 분석1998-2010년북경시호적거민악성림파류(간칭림파류)발병특점급류행추세.방법 통계북경시종류등기처1998-2010년림파류발병병례,공계9 763례,복개인구151 601 066인년.계산년도발병솔,중국인구결구표화솔(간칭중표솔),세계인구구성표화솔(간칭세표솔)이급년도평균변화솔(APC),루적발병솔화절축솔.분석불동성별、년령、지구인군적림파류적발병솔추세.결과 1998-2010년북경시림파류발병솔위6.48/10만(9 763/150 720 187),유1998년적3.78/10만(410/10 850 626)상승지2010년적8.88/10만(1 111/12 518 114),증장료136.17％,세표솔적APC위5.21％(P＜0.05);곽기금림파류발병솔유1998년적0.25/10만(27/10 850 626)상승지2010년적0.47/10만(59/12 518 114),증장료88.00％,세표솔적APC위4.33％ (P ＜0.05);비곽기금림파류발병솔유1998년적2.89/10만(314/10 850 626)상승지2010년적5.93/10만(742/12 518 114),증장료105.19％,세표발병솔적APC위4.19％ (P ＜0.05).1998-2010년북경성구림파류발병솔위7.78/10만(7 125/91 621 898),교구발병솔위4.47/10만(2 638/59 098 289),성교발병솔비위1.74;남성발병솔위7.40/10만(5 632/76 121 672),녀성위5.54/10만(4 131/74 598 518).결론 1998-2010년북경시림파류발병솔축년증고,남성고우녀성,성구고우교구,곽기금림파류여비곽기금림파류적발병솔불동.
Objective To analyze the incidence trends and characteristics of lymphoma in Beijing,1998-2010.Methods Total of 9 763 new cases diagnosed as lymphoma in 1998-2010 were extracted from the population-based database of Beijing Cancer Registry,covering population of 151 601 066 person-years.Incidence,age-adjusted incidence,cumulative incidence,truncated incidence and annual percentage change (APC) were calculated.The gender-specific,age-specific and pathology-specific incidence trends were analyzed.Result The incidence rate of lymphoma was 6.48/100 000 (9 763/150 720 187) during the period of 1998-2010,increased from 3.78/100 000 (410/10 850 626) in 1998 to 8.88/100 000 (1 111/12 518 114) in 2010 with an increasing rate of 136.17％ (APC =5.21％,P ＜ 0.05).The incidence rate of Hodgkin lymphoma increased from 0.25/100 000 (27/10 850 626) in 1998 to 0.47/100 000 (59/12 518 114) in 2010 with an increasing rate of 88.00％ (APC =4.33％,P ＜ 0.05).The incidence rate of non-Hodgkin lymphoma was increased from 2.89/100 000 (314/10 850 626) in 1998 to 5.93/100 000 (742/12 518 114) in 2010 with an increasing rate of 105.19％ (APC =4.19％,P ＜ 0.05).During the period of 1998-2010,the incidence of lymphoma was 7.78/100 000(7 125/91 621 898) in urban areas and 4.47/100 000(2 638/59 098 289)in rural areas,7.40/100 000(5 632/76 121 672) in males and 5.54/100 000 (4 131/74 598 518) in females.Conclusion The incidence of lymphoma keeps increasing in 1998-2010,and the incidence was higher in males than females,urban areas than rural areas.The incidence patterns of Hodgkin lymphoma and non-Hodgkin lymphoma were different.