中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2014年
10期
888-892
,共5页
李奎荣%周文慧%谷桂珍%周世义%郑玉新%余善法
李奎榮%週文慧%穀桂珍%週世義%鄭玉新%餘善法
리규영%주문혜%곡계진%주세의%정옥신%여선법
二硫化碳%职业暴露%神经系统
二硫化碳%職業暴露%神經繫統
이류화탄%직업폭로%신경계통
Carbon disulfide%Occupational exposure%Nervous system
目的 研究接触不同浓度二硫化碳(CS2)对作业工人神经系统体征异常检出率的影响.方法 收集某化纤厂2004-2011年间工作场所CS2浓度或作业工人个体接触CS2浓度的检测资料并进行处理,对该化纤厂3 464名接触CS2的作业工人分别进行肌力和肌张力、膝反射、跟腱反射、四肢感觉功能及三颤等神经系统体征检查;用x2检验的方法比较不同组间神经系统异常率的差异.结果 该化纤厂作业工人接触CS2的8h时间加权平均浓度为0.2~41.0 mg/m3,几何均数为2.38 mg/m3.其中1 771名作业工人接触CS2的浓度为0.2~2.5 mg/m3;642名作业工人接触CS2的浓度为2.6~4.8 mg/m3;1 051名作业工人接触CS2的浓度为5.1~41.0 mg/m3,大于5.0 mg/m3的职业接触限值标准.累积接触量为≤10.0、10.1 ~ 20.0、20.1 ~ 30.0、30.1 ~ 40.0、40.1 ~ 50.0、>50.0 mg/m3·年组的膝反射异常率为3.0%(31/1 045)、3.7%(21/574)、4.8%(16/331)、3.3%(10/305)、5.9% (11/187)、6.7% (68/1 022),差异有统计学意义(x2=19.53,P<0.01);跟腱反射异常率为2.2% (23/1 045)、3.7% (21/574)、2.7% (9/331)、2.3% (7/305)、2.1% (4/187)、5.6%(57/1 022),差异有统计学意义(x2=21.27,P<0.01);感觉功能异常率为0.4%(4/1 045)、0.5%(3/574)、0.6%(2/331)、0.0%(0/305)、2.1% (4/187)、1.7%(17/1 022),差异有统计学意义(x2=15.89,P<0.01).按年龄和性别分层统计结果,除≤25岁年龄段不同浓度组间跟腱反射异常率差异有统计学意义[接触浓度为≤2.5、2.6~5.0、≥5.0 mg/m3组跟腱反射异常率分别为0.4%(2/511)、1.0%(1/98)、2.1%(7/327),x2=5.59,P=0.045]外,其余各年龄段和各性别不同浓度组间神经系统各体征异常检出率差异无统计学意义(P>0.05).结论 接触CS2除对≤25岁年龄段跟腱反射异常率有影响外,对大部分年龄段和性别组作业工人神经系统各体征无明显影响.
目的 研究接觸不同濃度二硫化碳(CS2)對作業工人神經繫統體徵異常檢齣率的影響.方法 收集某化纖廠2004-2011年間工作場所CS2濃度或作業工人箇體接觸CS2濃度的檢測資料併進行處理,對該化纖廠3 464名接觸CS2的作業工人分彆進行肌力和肌張力、膝反射、跟腱反射、四肢感覺功能及三顫等神經繫統體徵檢查;用x2檢驗的方法比較不同組間神經繫統異常率的差異.結果 該化纖廠作業工人接觸CS2的8h時間加權平均濃度為0.2~41.0 mg/m3,幾何均數為2.38 mg/m3.其中1 771名作業工人接觸CS2的濃度為0.2~2.5 mg/m3;642名作業工人接觸CS2的濃度為2.6~4.8 mg/m3;1 051名作業工人接觸CS2的濃度為5.1~41.0 mg/m3,大于5.0 mg/m3的職業接觸限值標準.纍積接觸量為≤10.0、10.1 ~ 20.0、20.1 ~ 30.0、30.1 ~ 40.0、40.1 ~ 50.0、>50.0 mg/m3·年組的膝反射異常率為3.0%(31/1 045)、3.7%(21/574)、4.8%(16/331)、3.3%(10/305)、5.9% (11/187)、6.7% (68/1 022),差異有統計學意義(x2=19.53,P<0.01);跟腱反射異常率為2.2% (23/1 045)、3.7% (21/574)、2.7% (9/331)、2.3% (7/305)、2.1% (4/187)、5.6%(57/1 022),差異有統計學意義(x2=21.27,P<0.01);感覺功能異常率為0.4%(4/1 045)、0.5%(3/574)、0.6%(2/331)、0.0%(0/305)、2.1% (4/187)、1.7%(17/1 022),差異有統計學意義(x2=15.89,P<0.01).按年齡和性彆分層統計結果,除≤25歲年齡段不同濃度組間跟腱反射異常率差異有統計學意義[接觸濃度為≤2.5、2.6~5.0、≥5.0 mg/m3組跟腱反射異常率分彆為0.4%(2/511)、1.0%(1/98)、2.1%(7/327),x2=5.59,P=0.045]外,其餘各年齡段和各性彆不同濃度組間神經繫統各體徵異常檢齣率差異無統計學意義(P>0.05).結論 接觸CS2除對≤25歲年齡段跟腱反射異常率有影響外,對大部分年齡段和性彆組作業工人神經繫統各體徵無明顯影響.
목적 연구접촉불동농도이류화탄(CS2)대작업공인신경계통체정이상검출솔적영향.방법 수집모화섬엄2004-2011년간공작장소CS2농도혹작업공인개체접촉CS2농도적검측자료병진행처리,대해화섬엄3 464명접촉CS2적작업공인분별진행기력화기장력、슬반사、근건반사、사지감각공능급삼전등신경계통체정검사;용x2검험적방법비교불동조간신경계통이상솔적차이.결과 해화섬엄작업공인접촉CS2적8h시간가권평균농도위0.2~41.0 mg/m3,궤하균수위2.38 mg/m3.기중1 771명작업공인접촉CS2적농도위0.2~2.5 mg/m3;642명작업공인접촉CS2적농도위2.6~4.8 mg/m3;1 051명작업공인접촉CS2적농도위5.1~41.0 mg/m3,대우5.0 mg/m3적직업접촉한치표준.루적접촉량위≤10.0、10.1 ~ 20.0、20.1 ~ 30.0、30.1 ~ 40.0、40.1 ~ 50.0、>50.0 mg/m3·년조적슬반사이상솔위3.0%(31/1 045)、3.7%(21/574)、4.8%(16/331)、3.3%(10/305)、5.9% (11/187)、6.7% (68/1 022),차이유통계학의의(x2=19.53,P<0.01);근건반사이상솔위2.2% (23/1 045)、3.7% (21/574)、2.7% (9/331)、2.3% (7/305)、2.1% (4/187)、5.6%(57/1 022),차이유통계학의의(x2=21.27,P<0.01);감각공능이상솔위0.4%(4/1 045)、0.5%(3/574)、0.6%(2/331)、0.0%(0/305)、2.1% (4/187)、1.7%(17/1 022),차이유통계학의의(x2=15.89,P<0.01).안년령화성별분층통계결과,제≤25세년령단불동농도조간근건반사이상솔차이유통계학의의[접촉농도위≤2.5、2.6~5.0、≥5.0 mg/m3조근건반사이상솔분별위0.4%(2/511)、1.0%(1/98)、2.1%(7/327),x2=5.59,P=0.045]외,기여각년령단화각성별불동농도조간신경계통각체정이상검출솔차이무통계학의의(P>0.05).결론 접촉CS2제대≤25세년령단근건반사이상솔유영향외,대대부분년령단화성별조작업공인신경계통각체정무명현영향.
Objective To study the effects of exposed to different concentrations of carbon disulfide on neurological signs of workers.Methods Collection the information of concentration of carbon disulfide in the workplace or workers individuals exposed of a chemical fiber industry from 2004 to 2011,a total of 3 537 workers exposed to carbon disulfide were detected muscle strength and muscle tone,knee reflex,Achilles tendon reflex,trembling limbs,sensory function,and three chatter.Chi-square test was used for statistical analysis on abnormal neurological signs of workers.Results Eight hours time-weighted average concentration range of workers exposed to carbon disulfide in this chemical fiber industry was 0.2-41.0 mg/m3,geometric mean was 2.38 mg/m3.Concentration of carbon disulfide exposure of 1 771 workers was from 0.2 to 2.5 mg/m3 (≤ 2.5 mg/m3),642 workers was 2.6-4.8 mg/m3 (< 5.0 mg/m3),other 1 051 workers was from 5.1 to 41.0 mg/m3 (> 5.0 mg/m3) in all subjects.The different detection rates of knee reflex were 3.0% (31/1 045),3.7% (21/574),4.8% (16/331),3.3% (10/305),5.9% (11/187),6.7% (68/1 022),the different detection rates of Achilles tendon reflex were 2.2% (23/ 1 045),3.7%(21/574),2.7% (9/331),2.3% (7/305),2.1% (4/187),5.6% (57/1 022),the different detection rates of sensory dysfunction were 0.4% (4/1 045),0.5% (3/574),0.6% (2/331),0.0% (0/305),2.1% (4/187),1.7% (17/1 022) in different cumulative amount of contact groups(≤ 10.0,10.1-20.0,20.1-30.0,30.1-40.0,40.1-50.0,> 50.0 mg/m3 per year),and the differences were statistically significant(x2 =-19.53,21.27 and 15.89,all P values were < 0.01).Stratified according to age and gender,in addition to the ≤25 years group the difference of detection rate analysis on Achilles tendon reflex was statistically significant in the different concentration group(the ratio of on Achilles tendon reflex in the different groups of concentration of carbon disulfide exposure of 2.5,2.6-5.0,≥5.0 mg/m3 were 0.4% (2/511),1.0% (1/98),2.1% (7/327),x2 =5.59,P =0.045),the difference of detection rate analysis on neurological sign was not statistically significant in the different concentration group on the rest of the age and gender groups(P > 0.05).Conclusion Within the concentration range of the object of study contact actual,different concentrations of carbon disulfide in addition to individual neurological signs of individual ages influential,it has no significant effect on the various signs of nervous system of workers of most age and gender groups,expect the age below the 25 years old group.