CAJ | 학술논문

目的应用裂隙灯显微镜眼前节相干光断层扫描(OCT)观察超声乳化白内障吸除联合人工晶状体(IOL)植入术后眼前节组织的变化情况,探讨手术对眼前节结构的影响.方法前瞻性系列病例研究.使用海德堡公司裂隙灯显微镜眼前节OCT观察40例(44只眼)行超声乳化白内障吸除联合IOL植入术患者术前和术后1 d、1周、2周及1个月的眼前节组织变化情况.对所测量的数据进行重复测量设计资料的方差分析,用LSD法进行两两比较.结果中央及切口处角膜在术后第1天全部患者均明显增厚(与术前相比增厚分别为99.59μm,234.57μm;P=0.490),中央角膜厚度至术后1个月可恢复术前水平,而切口处角膜厚度还较术前厚约19.25μm(P=0.001);前房深度(ACD)和各项反映前房角宽度的指标(AOD500、AOD750、TISA500、TISA750)在术后各观察时间点,均较术前明显加深和加宽(均P<0.05);ACD虽在术后2周以内的变化不大(均P<0.05),但在术后1个月时还尚不能保持稳定;而前房角宽度的变化在术后早期就可基本保持稳定(均P>0.05).结论裂隙灯显微镜眼前节OCT可客观、定量评价白内障手术对眼前节形态特征的影响.
목적 응용렬극등현미경안전절상간광단층소묘(OCT)관찰초성유화백내장흡제연합인공정상체(IOL)식입술후안전절조직적변화정황,탐토수술대안전절결구적영향.방법 전첨성계렬병례연구.사용해덕보공사렬극등현미경안전절OCT관찰40례(44지안)행초성유화백내장흡제연합IOL식입술환자술전화술후1 d、1주、2주급1개월적안전절조직변화정황.대소측량적수거진행중복측량설계자료적방차분석,용LSD법진행량량비교.결과 중앙급절구처각막재술후제1천전부환자균명현증후(여술전상비증후분별위99.59μm,234.57μm;P=0.490),중앙각막후도지술후1개월가회복술전수평,이절구처각막후도환교술전후약19.25μm(P=0.001);전방심도(ACD)화각항반영전방각관도적지표(AOD500、AOD750、TISA500、TISA750)재술후각관찰시간점,균교술전명현가심화가관(균P<0.05);ACD수재술후2주이내적변화불대(균P<0.05),단재술후1개월시환상불능보지은정;이전방각관도적변화재술후조기취가기본보지은정(균P>0.05).결론 렬극등현미경안전절OCT가객관、정량평개백내장수술대안전절형태특정적영향.
Objective To investigate quantitative changes of the anterior segment configuration after clear corneal incision phacoemulsification and foldable intraocular lens (IOL) implantation with slit-lamp-adapted optical coherence tomography (SL-OCT). Methods In prospective consecutive case series, clear corneal incision phacoemulsification and foldable intraocular lens implantation were performed in 44 eyes of 40 patients. The changes of the anterior segment configuration were performed by SL-OCT before and 1 day, 1 week, 2 weeks and 1 month after surgery. SPSS 16.0 software was used to analyze statistical difference. Results For all patients, the central corneal thickness (CCT) and the incisional corneal thickness (ICT) increased significantly 1 day after surgery ( CCT increased 99. 59 μm, ICT increased 234. 57 μm;P = O. 490). At 1 month, the CCT almost had returned to baseline, but the ICT had been ticker about 19. 25 μm than baseline (P=0. 001) . The measurements of ACD, AODS00, AOD750, TISAS00, TISA750 also increased significantly 1 day after surgery. Although the ACD had no changes within 2 weeks( all P <0.05), it had been not stable. The changes of the width of the anterior chamber had been stable in the early period after surgery ( all P>0. 05). Conclusion The SL-OCT could impersonality and quantificationally evaluate the anterior segment changes induced by cataract surgery.