CAJ | 학술논문

目的探讨单纯老年性白内障人群中角膜球面像差的分布情况.方法回顾性系列病例研究.收集60岁以上单纯老年性白内障患者临床资料,共504例(922只眼),按年龄(1组:60 ～＜70岁,153例;2组:70～＜80岁251例;3组:80～≤90岁100例)分组.使用Pentacam眼前节诊断分析仪于白内障手术前测量角膜参数角膜平均屈光力(Km)值及后表面平均屈光力(Km)值,Zernike分析计算以角膜顶点为中心6 mm直径范围内的前、后表面及总角膜球面像差值.采用单因素方差分析对各角膜参数在不同年龄分组问进行比较,使用配对f检验进行双眼间比较.结果全部患者平均年龄(73.5±6.8)岁,角膜Km值(44.50±1.39)D,后表面Km值(-6.44±0.25)D,三组之间差异无统计学意义(F值分别为0.738和0.373,P＞0.05),年龄与角膜Km值及后表面Km值间无相关性(r值分别为-0.033和0.037,P＞0.05).角膜前表面球面像差l组(0.361 ±0.122) μm,2组(0.401±0.139) μm,3组(0.440±0.145) μm;后表面球面像差分别为(-0.122±0.035)μm,(-0.105 ±0.040)μm,(-0.090±0.043)μm;总角膜球面像差分别为(0.360 ±0.142) μm,(0.421±0.158).μm,(0.476 ±0.170) μm.角膜前、后表面及总角膜球差在三组间差异均有统计学意义(F值分别为10.561、20.937及17.257,P＜0.01).前、后表面及总角膜球面像差与年龄间的相关系数r值分别为0.203、0.288及0.258;P ＜0.01;前、后表面及总角膜球面像差在双眼间差异无统计学意义(t值分别为1.624、1.401及1.556;P＞ 0.05)且呈正相关(r值分别为0.524、0.833及0.540,P＜0.01).结论 60岁以上单纯老年性白内障人群的角膜球面像差平均值较普通人群大,并且前表面及总角膜球差随年龄增加而增大,后表面负性球差随年龄增加而减小,各角膜球面像差参数在双眼间存在高度相关性.
목적 탐토단순노년성백내장인군중각막구면상차적분포정황.방법 회고성계렬병례연구.수집60세이상단순노년성백내장환자림상자료,공504례(922지안),안년령(1조:60 ～＜70세,153례;2조:70～＜80세251례;3조:80～≤90세100례)분조.사용Pentacam안전절진단분석의우백내장수술전측량각막삼수각막평균굴광력(Km)치급후표면평균굴광력(Km)치,Zernike분석계산이각막정점위중심6 mm직경범위내적전、후표면급총각막구면상차치.채용단인소방차분석대각각막삼수재불동년령분조문진행비교,사용배대f검험진행쌍안간비교.결과 전부환자평균년령(73.5±6.8)세,각막Km치(44.50±1.39)D,후표면Km치(-6.44±0.25)D,삼조지간차이무통계학의의(F치분별위0.738화0.373,P＞0.05),년령여각막Km치급후표면Km치간무상관성(r치분별위-0.033화0.037,P＞0.05).각막전표면구면상차l조(0.361 ±0.122) μm,2조(0.401±0.139) μm,3조(0.440±0.145) μm;후표면구면상차분별위(-0.122±0.035)μm,(-0.105 ±0.040)μm,(-0.090±0.043)μm;총각막구면상차분별위(0.360 ±0.142) μm,(0.421±0.158).μm,(0.476 ±0.170) μm.각막전、후표면급총각막구차재삼조간차이균유통계학의의(F치분별위10.561、20.937급17.257,P＜0.01).전、후표면급총각막구면상차여년령간적상관계수r치분별위0.203、0.288급0.258;P ＜0.01;전、후표면급총각막구면상차재쌍안간차이무통계학의의(t치분별위1.624、1.401급1.556;P＞ 0.05)차정정상관(r치분별위0.524、0.833급0.540,P＜0.01).결론 60세이상단순노년성백내장인군적각막구면상차평균치교보통인군대,병차전표면급총각막구차수년령증가이증대,후표면부성구차수년령증가이감소,각각막구면상차삼수재쌍안간존재고도상관성.
Objective To investigate the distribution of the spherical aberration in people with senile cataract,in the interest of the customized selection of the intraocular lens in cataract surgeries and the future design of the intraocular lens.Methods Retrospective study.Analysis of 922 eyes from 504 patients over 60-years-old was made.Patients were subdivided into 3 age groups (153 patients of 60-＜ 70 years-old in group 1,251 patients of 70-＜ 80 years-old in group 2,100 patients of 80-≤90 years-old in group 3).Pentacam anterior segment analyzer (OCULUS,Germany) was used to measure the average corneal and posterior surface K-readings.The Zernike coefficients of corneal spherical aberration was calculated.The difference of corneal parameters among each age group was compared.Results The average age of all patients was (73.5 ± 6.8) years-old.The average corneal K-reading was (44.50 ± 1.39) D and the average K-reading of corneal posterior surface was (-6.44 ± 0.25) D.There was no difference among 3 age groups (F =0.738 and 0.373 retrospectively,P ＞ 0.05).The corneal and posterior surface average K-readings had no correlation with the age.The average spherical aberration of anterior corneal surface was (0.361 ± 0.122) μm in group 1,(0.401 ±0.139)μm in group 2 and (0.440 ±0.145) μm in group 3 respectively.The spherical aberration of posterior corneal surface was (-0.122 ± 0.035) μm,(-0.105 ± 0.040) μm and (-0.090-0.043)μm respectively.The total corneal spherical aberration was (0.360 ± 0.142)μm,(0.421 ±0.158)μm and (0.476 ±0.170)μm respectively.Significant differences were observed among 3 age groups (F =10.561,20.937 and 17.257 retrospectively,P ＜0.01).The spherical aberrations of the corneal anterior,posterior surface and total cornea had positive correlation with the age (r =0.203,0.288 and 0.258 respectively,P ＜0.01).The corneal spherical aberrations had no differences between fight and left eyes,and had significant positive correlation between both sides.Conclusions The people with senile cataract over 60-year-old had higher corneal spherical aberrations than other age.The corneal spherical aberrations increased with the age and had significant correlation inter-ocularly.